| # | Title | Journal | Year | Citations |
|---|
| 1 | The twenty-item Toronto Alexithymia scale—I. Item selection and cross-validation of the factor structure | Journal of Psychosomatic Research | 1994 | 3,870 |
| 2 | Deep Brain Stimulation for Treatment-Resistant Depression | Neuron | 2005 | 3,560 |
| 3 | The Eating Attitudes Test: an index of the symptoms of anorexia nervosa | Psychological Medicine | 1979 | 2,818 |
| 4 | Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine | Nature | 1991 | 1,967 |
| 5 | STOP Questionnaire | Anesthesiology | 2008 | 1,950 |
| 6 | The twenty-item Toronto Alexithymia scale—II. Convergent, discriminant, and concurrent validity | Journal of Psychosomatic Research | 1994 | 1,893 |
| 7 | Functional impact of global rare copy number variation in autism spectrum disorders | Nature | 2010 | 1,803 |
| 8 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 9 | Guidelines for Reporting Reliability and Agreement Studies (GRRAS) were proposed | Journal of Clinical Epidemiology | 2011 | 1,362 |
| 10 | Genome-wide association study identifies 30 loci associated with bipolar disorder | Nature Genetics | 2019 | 1,191 |
| 11 | A review of the long-term effects of child sexual abuse | Child Abuse and Neglect | 1992 | 1,109 |
| 12 | Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1 | Nature | 1991 | 1,103 |
| 13 | Clock-drawing: is it the ideal cognitive screening test? | International Journal of Geriatric Psychiatry | 2000 | 1,086 |
| 14 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 15 | Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder | Bipolar Disorders | 2018 | 1,079 |
| 16 | Serotonin Transporter Promoter Gain-of-Function Genotypes Are Linked to Obsessive-Compulsive Disorder | American Journal of Human Genetics | 2006 | 1,032 |
| 17 | Relationship Between Dopamine D2 Occupancy, Clinical Response, and Side Effects: A Double-Blind PET Study of First-Episode Schizophrenia | American Journal of Psychiatry | 2000 | 982 |
| 18 | Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies | Molecular Psychiatry | 2022 | 967 |
| 19 | Modulation of Cortical-Limbic Pathways in Major Depression | Archives of General Psychiatry | 2004 | 962 |
| 20 | Sedative hypnotics in older people with insomnia: meta-analysis of risks and benefits | BMJ: British Medical Journal | 2005 | 908 |
| 21 | Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression | Biological Psychiatry | 2008 | 865 |
| 22 | The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness | Lancet Psychiatry,the | 2019 | 815 |
| 23 | Modulation of Intracellular Cyclic AMP Levels by Different Human Dopamine D4 Receptor Variants | Journal of Neurochemistry | 1995 | 759 |
| 24 | High STOP-Bang score indicates a high probability of obstructive sleep apnoea | British Journal of Anaesthesia | 2012 | 747 |
| 25 | Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder | Canadian Journal of Psychiatry | 2016 | 746 |
| 26 | Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013 | Bipolar Disorders | 2013 | 740 |
| 27 | Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial | Lancet, The | 2018 | 706 |
| 28 | Role of Translocator Protein Density, a Marker of Neuroinflammation, in the Brain During Major Depressive Episodes | JAMA Psychiatry | 2015 | 700 |
| 29 | Melatonin—A pleiotropic, orchestrating regulator molecule | Progress in Neurobiology | 2011 | 680 |
| 30 | Being Inconsistent About Consistency: When Coefficient Alpha Does and Doesn't Matter | Journal of Personality Assessment | 2003 | 676 |
| 31 | Socio-cultural factors in the development of anorexia nervosa | Psychological Medicine | 1980 | 629 |
| 32 | Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA: a meta-analysis | Lancet, The | 2012 | 628 |
| 33 | Loneliness and social isolation during the COVID-19 pandemic | International Psychogeriatrics | 2020 | 625 |
| 34 | Sexual Revictimization | Trauma, Violence, and Abuse | 2005 | 624 |
| 35 | Perceived Discrimination and Depression: Moderating Effects of Coping, Acculturation, and Ethnic Support | American Journal of Public Health | 2003 | 619 |
| 36 | The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital | Cmaj | 2003 | 607 |
| 37 | Contribution of SHANK3 Mutations to Autism Spectrum Disorder | American Journal of Human Genetics | 2007 | 604 |
| 38 | Clinical and Theoretical Implications of 5-HT2 and D2 Receptor Occupancy of Clozapine, Risperidone, and Olanzapine in Schizophrenia | American Journal of Psychiatry | 1999 | 600 |
| 39 | The Burden of Schizophrenia on Caregivers | Pharmacoeconomics | 2008 | 592 |
| 40 | COGNITIVE DEFICITS AND FUNCTIONAL OUTCOMES IN MAJOR DEPRESSIVE DISORDER: DETERMINANTS, SUBSTRATES, AND TREATMENT INTERVENTIONS | Depression and Anxiety | 2013 | 586 |
| 41 | Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders | BMC Psychiatry | 2014 | 569 |
| 42 | The Alexithymia Construct: A Potential Paradigm for Psychosomatic Medicine | Psychosomatics | 1991 | 568 |
| 43 | Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders 1 1This study was registered with ClinicalTrials.gov (trial registry no. NCT00006157). | Gastroenterology | 2003 | 568 |
| 44 | Exercise and sleep | Sleep Medicine Reviews | 2000 | 566 |
| 45 | Guidelines for Reporting Reliability and Agreement Studies (GRRAS) were proposed | International Journal of Nursing Studies | 2011 | 552 |
| 46 | The Brain-Derived Neurotrophic Factor Gene Confers Susceptibility to Bipolar Disorder: Evidence from a Family-Based Association Study | American Journal of Human Genetics | 2002 | 544 |
| 47 | Vagus Nerve Stimulation for Treatment-Resistant Depression: A Randomized, Controlled Acute Phase Trial | Biological Psychiatry | 2005 | 542 |
| 48 | A genome-wide scan for common alleles affecting risk for autism | Human Molecular Genetics | 2010 | 538 |
| 49 | What Do We Really Know About Mindfulness-Based Stress Reduction? | Psychosomatic Medicine | 2002 | 527 |
| 50 | Psychological Treatments for the World: Lessons from Low- and Middle-Income Countries | Annual Review of Clinical Psychology | 2017 | 524 |
