| # | Title | Journal | Year | Citations |
|---|
| 1 | Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target | American Journal of Gastroenterology | 2015 | 1,425 |
| 2 | Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma | Gastroenterology | 2016 | 1,365 |
| 3 | MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma | Cell | 1996 | 833 |
| 4 | Management of hepatitis B: 2000—Summary of a workshop | Gastroenterology | 2001 | 748 |
| 5 | The management of ascites in cirrhosis: Report on the consensus conference of the International Ascites Club | Hepatology | 2003 | 744 |
| 6 | Cardiac morbidity and mortality related to orthotopic liver transplantation | Liver Transplantation | 2004 | 682 |
| 7 | Association of Trough Serum Infliximab to Clinical Outcome After Scheduled Maintenance Treatment for Crohn’s Disease | Clinical Gastroenterology and Hepatology | 2006 | 586 |
| 8 | Diagnosis and management of acute kidney injury in patients with cirrhosis: Revised consensus recommendations of the International Club of Ascites | Journal of Hepatology | 2015 | 571 |
| 9 | Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders 1 1This study was registered with ClinicalTrials.gov (trial registry no. NCT00006157). | Gastroenterology | 2003 | 568 |
| 10 | 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B | Gastroenterology | 2009 | 527 |
| 11 | Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis | Postgraduate Medical Journal | 2008 | 504 |
| 12 | Folate and carcinogenesis: evidence, mechanisms, and implications | Journal of Nutritional Biochemistry | 1999 | 496 |
| 13 | Development of the Crohnʼs disease digestive damage score, the Lémann score | Inflammatory Bowel Diseases | 2011 | 496 |
| 14 | Transjugular Intrahepatic Portosystemic Shunt for Refractory Ascites: A Meta-analysis of Individual Patient Data | Gastroenterology | 2007 | 494 |
| 15 | Trough serum infliximab: a predictive factor of clinical outcome for infliximab treatment in acute ulcerative colitis | Gut | 2010 | 484 |
| 16 | Meta-analysis of enteral nutrition as a primary treatment of active crohn's disease | Gastroenterology | 1995 | 441 |
| 17 | Lamivudine treatment for decompensated cirrhosis resulting from chronic hepatitis B | Hepatology | 2000 | 435 |
| 18 | Outcome in patients with bifurcation tumors who undergo unilateral versus bilateral hepatic duct drainage | Gastrointestinal Endoscopy | 1998 | 405 |
| 19 | Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites | Gut | 2015 | 405 |
| 20 | Management of primary biliary cirrhosis | Hepatology | 2000 | 389 |
| 21 | Midodrine, octreotide, albumin, and TIPS in selected patients with cirrhosis and type 1 hepatorenal syndrome | Hepatology | 2004 | 369 |
| 22 | Second infections independently increase mortality in hospitalized patients With cirrhosis: the north american consortium for the study of end-stage liver disease (NACSELD) experience | Hepatology | 2012 | 357 |
| 23 | Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis | Nature Genetics | 2013 | 339 |
| 24 | Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club | Gut | 2005 | 336 |
| 25 | Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data | Gut | 2009 | 324 |
| 26 | Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers | Nature Genetics | 2015 | 306 |
| 27 | Clinical Practice Guidelines for the Use of Video Capsule Endoscopy | Gastroenterology | 2017 | 306 |
| 28 | Screening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: Incidence and prevalence of hepatocellular carcinoma in a North American urban population | Hepatology | 1995 | 305 |
| 29 | Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide | Gastroenterology | 2019 | 296 |
| 30 | Quality of care in for-profit and not-for-profit nursing homes: systematic review and meta-analysis | BMJ: British Medical Journal | 2009 | 290 |
| 31 | Will mandatory folic acid fortification prevent or promote cancer? | American Journal of Clinical Nutrition | 2004 | 275 |
| 32 | Design of Treatment Trials for Functional Gastrointestinal Disorders | Gastroenterology | 2006 | 269 |
| 33 | Therapeutic drug monitoring of immunosuppressant drugs in clinical practice | Clinical Therapeutics | 2002 | 264 |
| 34 | Diverticular Disease: Epidemiology and Management | Canadian Journal of Gastroenterology & Hepatology | 2011 | 250 |
| 35 | Functional gastrointestinal disorders and mood disorders in patients with inactive inflammatory bowel disease: Prevalence and impact on health | Inflammatory Bowel Diseases | 2006 | 249 |
| 36 | Familial enteropathy: A syndrome of protracted diarrhea from birth, failure to thrive, and hypoplastic villus atrophy | Gastroenterology | 1978 | 243 |
| 37 | The cardiac response to exercise in cirrhosis | Gut | 2001 | 237 |
| 38 | New Consensus Definition of Acute Kidney Injury Accurately Predicts 30-Day Mortality in Patients With Cirrhosis and Infection | Gastroenterology | 2013 | 221 |
| 39 | Increased Perioperative Mortality Following Bariatric Surgery Among Patients With Cirrhosis | Clinical Gastroenterology and Hepatology | 2011 | 217 |
| 40 | AGA Clinical Practice Guidelines on the Role of Probiotics in the Management of Gastrointestinal Disorders | Gastroenterology | 2020 | 209 |
| 41 | Acute kidney injury in decompensated cirrhosis | Gut | 2013 | 205 |
| 42 | Disease Progression in Chronic Hepatitis C: Modifiable and Nonmodifiable Factors | Gastroenterology | 2008 | 200 |
| 43 | In vivo Near-infrared Raman Spectroscopy: Demonstration of Feasibility During Clinical Gastrointestinal Endoscopy ¶ | Photochemistry and Photobiology | 2000 | 193 |
| 44 | The impact of a gluten-free diet on adults with coeliac disease: results of a national survey | Journal of Human Nutrition and Dietetics | 2006 | 185 |
| 45 | Role of infant feeding practices in development of Crohn's disease in childhood. | BMJ: British Medical Journal | 1989 | 184 |
| 46 | Electrohydraulic Lithotripsy in 111 Patients: A Safe and Effective Therapy for Difficult Bile Duct Stones | American Journal of Gastroenterology | 2004 | 178 |
| 47 | Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease | Nature Communications | 2017 | 176 |
| 48 | Hepatorenal syndrome | Nature Reviews Disease Primers | 2018 | 172 |
| 49 | Portopulmonary hypertension in decompensated cirrhosis with refractory ascites | Gut | 2003 | 163 |
| 50 | A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis | Mucosal Immunology | 2012 | 163 |
