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exaly
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Department of Health Chemistry
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top-articles
Department of Health Chemistry
151
(top 1%)
papers
11.8K
(top 1%)
citations
57
(top 1%)
h
-index
107
(top 1%)
g
-index
158
all documents
12.1K
doc citations
1.7K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2
Journal of Biological Chemistry
2000
838
2
Molecular Identification of Cytosolic Prostaglandin E2 Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E2Biosynthesis
Journal of Biological Chemistry
2000
643
3
Phospholipase A2 enzymes
Prostaglandins and Other Lipid Mediators
2002
632
4
Regulatory Functions of Phospholipase A2
Critical Reviews in Immunology
1997
479
5
Phospholipase A2
Journal of Biochemistry
2002
453
6
The Functions of Five Distinct Mammalian Phospholipase A2s in Regulating Arachidonic Acid Release
Journal of Biological Chemistry
1998
352
7
Functional Coupling Between Various Phospholipase A2s and Cyclooxygenases in Immediate and Delayed Prostanoid Biosynthetic Pathways
Journal of Biological Chemistry
1999
328
8
Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway
Progress in Lipid Research
2004
314
9
Cellular Prostaglandin E2 Production by Membrane-bound Prostaglandin E Synthase-2 via Both Cyclooxygenases-1 and -2
Journal of Biological Chemistry
2003
300
10
Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1
Journal of Biological Chemistry
2004
257
11
Prostaglandin E synthase
Prostaglandins and Other Lipid Mediators
2002
219
12
Fas-induced Arachidonic Acid Release Is Mediated by Ca2+-independent Phospholipase A2 but Not Cytosolic Phospholipase A2, Which Undergoes Proteolytic Inactivation
Journal of Biological Chemistry
1998
208
13
Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D
Biochemical Journal
2004
206
14
Cytosolic Phospholipase A2 Is Required for Cytokine-induced Expression of Type IIA Secretory Phospholipase A2 That Mediates Optimal Cyclooxygenase-2-dependent Delayed Prostaglandin E2 Generation in Rat 3Y1 Fibroblasts
Journal of Biological Chemistry
1998
181
15
Potential Role of Microsomal Prostaglandin E Synthase-1 in Tumorigenesis
Journal of Biological Chemistry
2003
171
16
Distinct Arachidonate-releasing Functions of Mammalian Secreted Phospholipase A2s in Human Embryonic Kidney 293 and Rat Mastocytoma RBL-2H3 Cells through Heparan Sulfate Shuttling and External Plasma Membrane Mechanisms
Journal of Biological Chemistry
2001
162
17
Functional Association of Type IIA Secretory Phospholipase A2 with the Glycosylphosphatidylinositol-anchored Heparan Sulfate Proteoglycan in the Cyclooxygenase-2-mediated Delayed Prostanoid-biosynthetic Pathway
Journal of Biological Chemistry
1999
160
18
Different Functional Aspects of the Group II Subfamily (Types IIA and V) and Type X Secretory Phospholipase A2s in Regulating Arachidonic Acid Release and Prostaglandin Generation
Journal of Biological Chemistry
1999
158
19
A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa
Inflammation Research
1999
154
20
Distinct Roles of Two Intracellular Phospholipase A2s in Fatty Acid Release in the Cell Death Pathway
Journal of Biological Chemistry
2000
153
21
Concordant Induction of Prostaglandin E2Synthase with Cyclooxygenase-2 Leads to Preferred Production of Prostaglandin E2over Thromboxane and Prostaglandin D2in Lipopolysaccharide-Stimulated Rat Peritoneal Macrophages
Biochemical and Biophysical Research Communications
1997
142
22
Prostaglandin E Synthase: A Novel Drug Target for Inflammation and Cancer
Current Pharmaceutical Design
2006
138
23
Diversity and regulatory functions of mammalian secretory phospholipase A2s
Advances in Immunology
2001
135
24
Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models
Biochimie
2010
135
25
Type II Secretory Phospholipase A2 Associated with Cell Surfaces via C-terminal Heparin-binding Lysine Residues Augments Stimulus-initiated Delayed Prostaglandin Generation
Journal of Biological Chemistry
1996
133
26
Secretory Phospholipase A2
Biological and Pharmaceutical Bulletin
2004
124
27
Prostaglandin E Synthase, a Terminal Enzyme for Prostaglandin E
2
Biosynthesis
BMB Reports
2005
120
28
Lymphoid tissue phospholipase A2 group IID resolves contact hypersensitivity by driving antiinflammatory lipid mediators
Journal of Experimental Medicine
2013
119
29
Prostaglandin E2 Amplifies Cytosolic Phospholipase A2- and Cyclooxygenase-2-dependent Delayed Prostaglandin E2 Generation in Mouse Osteoblastic Cells
Journal of Biological Chemistry
1997
118
30
Invivo ESR measurement of free radicals in whole mice
Biochemical and Biophysical Research Communications
1990
115
31
Lipid Mediators in Life Science
Experimental Animals
2011
113
32
The Adipocyte-Inducible Secreted Phospholipases PLA2G5 and PLA2G2E Play Distinct Roles in Obesity
Cell Metabolism
2014
110
33
Coupling between cyclooxygenases and terminal prostanoid synthases
Biochemical and Biophysical Research Communications
2005
107
34
Analyses of Group III Secreted Phospholipase A2 Transgenic Mice Reveal Potential Participation of This Enzyme in Plasma Lipoprotein Modification, Macrophage Foam Cell Formation, and Atherosclerosis
Journal of Biological Chemistry
2008
107
35
ESR measurement of radical clearance in lung of whole mouse
Biochemical and Biophysical Research Communications
1991
96
36
The perturbed membrane of cells undergoing apoptosis is susceptible to type II secretory phospholipase A2 to liberate arachidonic acid
Lipids and Lipid Metabolism
1997
95
37
Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality because of Lung Dysfunction
Journal of Biological Chemistry
2006
89
38
Identification of a Cellular Protein That Functionally Interacts with the C2 Domain of Cytosolic Phospholipase A2α
Journal of Biological Chemistry
2000
86
39
Regulation of type V phospholipase A2 expression and function by proinflammatory stimuli
FEBS Journal
1999
85
40
Phospholipase A2mediates ischemic injury in the hippocampus: a regional difference of neuronal vulnerability
European Journal of Neuroscience
2001
82
41
Antioxidant Activity of Nitroxide Radicals in Lipid Peroxidation of Rat Liver Microsomes
Archives of Biochemistry and Biophysics
1993
81
42
Effects of inspired oxygen concentration on in vivo redox reaction of nitroxide radicals in whole mice
Biochemical and Biophysical Research Communications
1992
80
43
Cellular components that functionally interact with signaling phospholipase A2s
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids
2000
79
44
Mechanisms related to reduction of radical in mouse lung using an L-band ESR spectrometer
Free Radical Biology and Medicine
1999
78
45
Expression of secretory phospholipase A2 enzymes in lungs of humans with pneumonia and their potential prostaglandin-synthetic function in human lung-derived cells
Biochemical Journal
2005
77
46
Regulatory Functions of Phospholipase A2
Critical Reviews in Immunology
2017
75
47
New phospholipase A2 isozymes with a potential role in atherosclerosis
Current Opinion in Lipidology
2003
73
48
Cellular Arachidonate-releasing Function of Novel Classes of Secretory Phospholipase A2s (Groups III and XII)
Journal of Biological Chemistry
2003
71
49
Induction of cyclooxygenase-2 by secretory phospholipases A2 in nerve growth factor-stimulated rat serosal mast cells is facilitated by interaction with fibroblasts and mediated by a mechanism independent of their enzymatic functions
Journal of Immunology
1998
69
50
Induction of Cyclooxygenase-2 by Secretory Phospholipases A2 in Nerve Growth Factor-Stimulated Rat Serosal Mast Cells Is Facilitated by Interaction with Fibroblasts and Mediated by a Mechanism Independent of Their Enzymatic Functions
Journal of Immunology
1998
69
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