| # | Title | Journal | Year | Citations |
|---|
| 1 | Identification and Characterization of Tumorigenic Liver Cancer Stem/Progenitor Cells | Gastroenterology | 2007 | 1,096 |
| 2 | CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway | Oncogene | 2008 | 720 |
| 3 | Genomic instability in laminopathy-based premature aging | Nature Medicine | 2005 | 579 |
| 4 | A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening | Cell Stem Cell | 2018 | 445 |
| 5 | Radiotherapy toxicity | Nature Reviews Disease Primers | 2019 | 434 |
| 6 | Aldehyde Dehydrogenase Discriminates the CD133 Liver Cancer Stem Cell Populations | Molecular Cancer Research | 2008 | 427 |
| 7 | Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma | Nature Medicine | 2013 | 421 |
| 8 | An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival | Journal of Experimental Medicine | 2008 | 419 |
| 9 | miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1 | Cell Stem Cell | 2010 | 368 |
| 10 | Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma | Journal of Hepatology | 2015 | 312 |
| 11 | Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract | Nature Medicine | 2007 | 303 |
| 12 | Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia | Nature Genetics | 2012 | 286 |
| 13 | MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression | Hepatology | 2011 | 276 |
| 14 | Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study | Journal of Clinical Oncology | 2004 | 254 |
| 15 | Long-Term Survival After Cisplatin-Based Induction Chemotherapy and Radiotherapy for Nasopharyngeal Carcinoma: A Pooled Data Analysis of Two Phase III Trials | Journal of Clinical Oncology | 2005 | 227 |
| 16 | MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor | Gut | 2012 | 223 |
| 17 | Intensity-modulated radiotherapy for early-stage nasopharyngeal carcinoma | Cancer | 2004 | 219 |
| 18 | COVID‐19 pandemic: Effects and evidence‐based recommendations for otolaryngology and head and neck surgery practice | Head and Neck | 2020 | 218 |
| 19 | Circulating microRNAs as Specific Biomarkers for Breast Cancer Detection | PLoS ONE | 2013 | 212 |
| 20 | Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells | Oncogene | 2004 | 208 |
| 21 | Association of Vimentin overexpression and hepatocellular carcinoma metastasis | Oncogene | 2004 | 205 |
| 22 | Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy | International Journal of Radiation Oncology Biology Physics | 2004 | 199 |
| 23 | Prognostic significance ofc-myc andAIB1 amplification in hepatocellular carcinoma | Cancer | 2002 | 192 |
| 24 | Treatment outcomes of nasopharyngeal carcinoma in modern era after intensity modulated radiotherapy (IMRT) in Hong Kong: A report of 3328 patients (HKNPCSG 1301 study) | Oral Oncology | 2018 | 189 |
| 25 | Cancer stem cells in hepatocellular carcinoma — from origin to clinical implications | Nature Reviews Gastroenterology and Hepatology | 2022 | 185 |
| 26 | A Systematic Review and Meta-Analysis of Prophylactic Central Neck Dissection on Short-Term Locoregional Recurrence in Papillary Thyroid Carcinoma After Total Thyroidectomy | Thyroid | 2013 | 184 |
| 27 | MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN | Carcinogenesis | 2013 | 181 |
| 28 | Interleukin 17A Promotes Hepatocellular Carcinoma Metastasis via NF-kB Induced Matrix Metalloproteinases 2 and 9 Expression | PLoS ONE | 2011 | 168 |
| 29 | Lung metastasis alone in nasopharyngeal carcinoma: A relatively favorable prognostic group | Cancer | 2004 | 167 |
| 30 | Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance | Oncogene | 2016 | 167 |
| 31 | Preliminary results of radiation dose escalation for locally advanced nasopharyngeal carcinoma | International Journal of Radiation Oncology Biology Physics | 2006 | 166 |
| 32 | Survival outcome of patients with nasopharyngeal carcinoma with first local failure: A study by the Hong Kong Nasopharyngeal Carcinoma Study Group | Head and Neck | 2005 | 157 |
| 33 | Health Benefits and Molecular Mechanisms of Resveratrol: A Narrative Review | Foods | 2020 | 156 |
| 34 | Sustained elevation of Epstein–Barr virus antibody levels preceding clinical onset of nasopharyngeal carcinoma | British Journal of Cancer | 2007 | 155 |
| 35 | Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial–mesenchymaltransition | Gut | 2012 | 153 |
| 36 | High-level expression of Rad51 is an independent prognostic marker of survival in non-small-cell lung cancer patients | British Journal of Cancer | 2005 | 152 |
| 37 | Preliminary results of trial NPC‐0501 evaluating the therapeutic gain by changing from concurrent‐adjuvant to induction‐concurrent chemoradiotherapy, changing from fluorouracil to capecitabine, and changing from conventional to accelerated radiotherapy fractionation in patients with locoregionally advanced nasopharyngeal carcinoma | Cancer | 2015 | 152 |
| 38 | Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization | Genes Chromosomes and Cancer | 2000 | 147 |
| 39 | Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 144 |
| 40 | Comparative proteomic analysis of esophageal squamous cell carcinoma | Proteomics | 2005 | 142 |
| 41 | LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis | Breast Cancer Research and Treatment | 2012 | 142 |
| 42 | Insights into Endothelial Progenitor Cells: Origin, Classification, Potentials, and Prospects | Stem Cells International | 2018 | 142 |
| 43 | The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update | Protein and Cell | 2014 | 141 |
| 44 | Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma | Hepatology | 2010 | 138 |
| 45 | Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development | Nature Communications | 2017 | 137 |
| 46 | Treatment outcome after radiotherapy alone for patients with Stage I-II nasopharyngeal carcinoma | Cancer | 2003 | 135 |
| 47 | Clusterin plays an important role in hepatocellular carcinoma metastasis | Oncogene | 2006 | 134 |
| 48 | CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients | Journal of Clinical Investigation | 2010 | 132 |
| 49 | Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis | Journal of Pathology | 2003 | 131 |
| 50 | Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma | Hepatology | 2008 | 128 |
