| MultiQC: summarize analysis results for multiple tools and samples in a single report | Bioinformatics | 2016 | 1.7K |
| Visualization and analysis of gene expression in tissue sections by spatial transcriptomics | Science | 2016 | 944 |
| Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2 | ELife | 2016 | 712 |
| Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells | Cell | 2016 | 425 |
| Signaling Receptors for TGF-β Family Members | Cold Spring Harbor Perspectives in Biology | 2016 | 287 |
| Structural genomic changes underlie alternative reproductive strategies in the ruff (Philomachus pugnax) | Nature Genetics | 2016 | 214 |
| Organization and Regulation of Mitochondrial Protein Synthesis | Annual Review of Biochemistry | 2016 | 155 |
| Mechanisms of TGFβ-Induced Epithelial-Mesenchymal Transition | Journal of Clinical Medicine | 2016 | 150 |
| Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease | European Journal of Medicinal Chemistry | 2016 | 145 |
| Transforming growth factor β as regulator of cancer stemness and metastasis | British Journal of Cancer | 2016 | 134 |
| Standardized benchmarking in the quest for orthologs | Nature Methods | 2016 | 133 |
| Heparan Sulfate: Biosynthesis, Structure, and Function | International Review of Cell and Molecular Biology | 2016 | 124 |
| Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity | Nature Communications | 2016 | 120 |
| Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma | Nature Medicine | 2016 | 115 |
| A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors | Molecular Cell | 2016 | 110 |
| Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction | Nature Biotechnology | 2016 | 105 |
| The genetic basis for ecological adaptation of the Atlantic herring revealed by genome sequencing | ELife | 2016 | 103 |
| Estrogen receptor beta as target for colorectal cancer prevention | Cancer Letters | 2016 | 96 |
| Role of ribosomal protein mutations in tumor development (Review) | International Journal of Oncology | 2016 | 93 |
| Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification | Nature | 2016 | 90 |
| Targeting DNA repair, DNA metabolism and replication stress as anti-cancer strategies | FEBS Journal | 2016 | 84 |
| USP7 is a SUMO deubiquitinase essential for DNA replication | Nature Structural and Molecular Biology | 2016 | 82 |
| Validation and development of MTH1 inhibitors for treatment of cancer | Annals of Oncology | 2016 | 77 |
| Enantioselective Organocatalyzed Transformations of β-Ketoesters | Chemical Reviews | 2016 | 76 |
| Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities | Cell Reports | 2016 | 72 |
