| Mechanisms underlying mutational signatures in human cancers | Nature Reviews Genetics | 2014 | 514 |
| Low gut microbiota diversity in early infancy precedes asthma at school age | Clinical and Experimental Allergy | 2014 | 435 |
| The genomic landscape underlying phenotypic integrity in the face of gene flow in crows | Science | 2014 | 372 |
| MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool | Nature | 2014 | 326 |
| SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability | Cell Reports | 2014 | 280 |
| Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy | Nature | 2014 | 272 |
| Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 244 |
| Genomic diversity and admixture differs for Stone-Age Scandinavian foragers and farmers | Science | 2014 | 232 |
| DegePrime, a program for degenerate primer design for broad-taxonomic-range PCR in microbial ecology studies | Applied and Environmental Microbiology | 2014 | 210 |
| Thiamin function, metabolism, uptake, and transport | Biochemistry | 2014 | 171 |
| The environmental release and fate of antibiotics | Marine Pollution Bulletin | 2014 | 152 |
| Single-particle tracking reveals that free ribosomal subunits are not excluded from the Escherichia coli nucleoid | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 121 |
| Direct measurement of transcription factor dissociation excludes a simple operator occupancy model for gene regulation | Nature Genetics | 2014 | 108 |
| Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity | Cell Reports | 2014 | 99 |
| Lactase persistence alleles reveal partial East African ancestry of southern African Khoe pastoralists | Current Biology | 2014 | 83 |
| Chemical properties, environmental fate, and degradation of seven classes of pollutants | Chemical Research in Toxicology | 2014 | 78 |
| PconsFold: improved contact predictions improve protein models | Bioinformatics | 2014 | 76 |
| Rational design and validation of a Tip60 histone acetyltransferase inhibitor | Scientific Reports | 2014 | 70 |
| Genetic variation reveals large-scale population expansion and migration during the expansion of Bantu-speaking peoples | Proceedings of the Royal Society B: Biological Sciences | 2014 | 66 |
| The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations | Bioinformatics | 2014 | 62 |
| The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions | Nucleic Acids Research | 2014 | 59 |
| Variability of the transporter gene complement in ammonia-oxidizing archaea | Trends in Microbiology | 2014 | 56 |
| Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 55 |
| Distinguishing between driver and passenger mutations in individual cancer genomes by network enrichment analysis | BMC Bioinformatics | 2014 | 50 |
| Genome of the avirulent human-infective trypanosome--Trypanosoma rangeli | PLoS Neglected Tropical Diseases | 2014 | 49 |
