| # | Title | Journal | Year | Citations |
|---|
| 1 | Waves of resistance: Staphylococcus aureus in the antibiotic era | Nature Reviews Microbiology | 2009 | 2,049 |
| 2 | Requirement for IL-13 Independently of IL-4 in Experimental Asthma | Science | 1998 | 1,801 |
| 3 | Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus | Lancet, The | 2006 | 1,440 |
| 4 | Nicotine Addiction | New England Journal of Medicine | 2010 | 1,196 |
| 5 | Community-associated meticillin-resistant Staphylococcus aureus | Lancet, The | 2010 | 1,178 |
| 6 | HIV Infection, Inflammation, Immunosenescence, and Aging | Annual Review of Medicine | 2011 | 1,109 |
| 7 | Food Insecurity Is Associated with Chronic Disease among Low-Income NHANES Participants | Journal of Nutrition | 2010 | 1,081 |
| 8 | Do Professional Interpreters Improve Clinical Care for Patients with Limited English Proficiency? A Systematic Review of the Literature | Health Services Research | 2007 | 1,043 |
| 9 | Acute Exacerbations of Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2007 | 996 |
| 10 | Closing the Loop | Archives of Internal Medicine | 2003 | 967 |
| 11 | Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection | Journal of Infectious Diseases | 2011 | 957 |
| 12 | Vitamin D–Binding Protein and Vitamin D Status of Black Americans and White Americans | New England Journal of Medicine | 2013 | 898 |
| 13 | T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy | Journal of Infectious Diseases | 2003 | 786 |
| 14 | Predicting Survival in Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2001 | 757 |
| 15 | Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection | Journal of Experimental Medicine | 2008 | 681 |
| 16 | Pharmacology of Nicotine: Addiction, Smoking-Induced Disease, and Therapeutics | Annual Review of Pharmacology and Toxicology | 2009 | 664 |
| 17 | Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilli | Lancet, The | 1999 | 663 |
| 18 | Factors Associated With the Health Care Utilization of Homeless Persons | JAMA - Journal of the American Medical Association | 2001 | 576 |
| 19 | Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2001 | 562 |
| 20 | Progression of Atherosclerosis as Assessed by Carotid Intima-Media Thickness in Patients With HIV Infection | Circulation | 2004 | 552 |
| 21 | Nicotine Metabolism and Intake in Black and White Smokers | JAMA - Journal of the American Medical Association | 1998 | 546 |
| 22 | Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans | Nature Medicine | 1999 | 544 |
| 23 | Chemical genetics of Plasmodium falciparum | Nature | 2010 | 515 |
| 24 | Expression of AT2 receptors in the developing rat fetus. | Journal of Clinical Investigation | 1991 | 500 |
| 25 | Increased production of IL-7 accompanies HIV-1–mediated T-cell depletion: implications for T-cell homeostasis | Nature Medicine | 2001 | 498 |
| 26 | Racial Differences in Incident Heart Failure among Young Adults | New England Journal of Medicine | 2009 | 483 |
| 27 | Ineffectiveness of High-dose Methylprednisolone in Preventing Parenchymal Lung Injury and Improving Mortality in Patients with Septic Shock | The American Review of Respiratory Disease | 1988 | 482 |
| 28 | Cardiovascular Toxicity of Nicotine: Implications for Nicotine Replacement Therapy 11All editorial decisions for this article, including selection of referees, were made by a Guest Editor. This policy applies to all articles with authors from the University of California San Francisco. | Journal of the American College of Cardiology | 1997 | 476 |
| 29 | Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes | Nature Genetics | 2012 | 475 |
| 30 | Loss of integrin αvβ6-mediated TGF-β activation causes Mmp12-dependent emphysema | Nature | 2003 | 468 |
| 31 | Soluble Markers of Inflammation and Coagulation but Not T-Cell Activation Predict Non–AIDS-Defining Morbid Events During Suppressive Antiretroviral Treatment | Journal of Infectious Diseases | 2014 | 464 |
| 32 | Cotinine disposition and effects | Clinical Pharmacology and Therapeutics | 1983 | 434 |
| 33 | Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1 | Nature Medicine | 1998 | 395 |
| 34 | Functional health literacy and the quality of physician–patient communication among diabetes patients | Patient Education and Counseling | 2004 | 389 |
| 35 | Low-Dose Compared with Standard-Dose m-BACOD Chemotherapy for Non-Hodgkin's Lymphoma Associated with Human Immunodeficiency Virus Infection | New England Journal of Medicine | 1997 | 378 |
| 36 | The Arginine Catabolic Mobile Element and Staphylococcal Chromosomal CassettemecLinkage: Convergence of Virulence and Resistance in the USA300 Clone of Methicillin‐ResistantStaphylococcus aureus | Journal of Infectious Diseases | 2008 | 378 |
| 37 | Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity*1 | Clinical Pharmacology and Therapeutics | 2004 | 366 |
| 38 | Hyperlipidemia and Insulin Resistance Are Induced by Protease Inhibitors Independent of Changes in Body Composition in Patients With HIV Infection | Journal of Acquired Immune Deficiency Syndromes (1999) | 2000 | 338 |
| 39 | Severe Bile Salt Export Pump Deficiency: 82 Different ABCB11 Mutations in 109 Families | Gastroenterology | 2008 | 331 |
| 40 | Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis | Aids | 2009 | 324 |
| 41 | Characterization of Native and Recombinant Falcipain-2, a Principal Trophozoite Cysteine Protease and Essential Hemoglobinase ofPlasmodium falciparum | Journal of Biological Chemistry | 2000 | 317 |
| 42 | Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11 | Gastroenterology | 2004 | 316 |
| 43 | A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum. | Journal of Clinical Investigation | 1988 | 314 |
| 44 | A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease | American Journal of Kidney Diseases | 2022 | 314 |
| 45 | The Literacy Divide: Health Literacy and the Use of an Internet-Based Patient Portal in an Integrated Health System—Results from the Diabetes Study of Northern California (DISTANCE) | Journal of Health Communication | 2010 | 305 |
| 46 | Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT | Nature Genetics | 2003 | 302 |
| 47 | Artemisinin activity againstPlasmodium falciparumrequires hemoglobin uptake and digestion | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 293 |
| 48 | Use of 16S rRNA Gene for Identification of a Broad Range of Clinically Relevant Bacterial Pathogens | PLoS ONE | 2015 | 293 |
| 49 | Cysteine proteases of malaria parasites | International Journal for Parasitology | 2004 | 281 |
| 50 | TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection | PLoS Pathogens | 2016 | 271 |
