| Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 1.3K |
| Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study | Intensive Care Medicine | 2015 | 1.1K |
| Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events | Circulation | 2002 | 907 |
| Homocysteine and vascular disease | Lancet, The | 1999 | 758 |
| Markers of bone turnover for the prediction of fracture risk and monitoring of osteoporosis treatment: a need for international reference standards | Osteoporosis International | 2011 | 698 |
| Patients with prior myocardial infarction, stroke, or symptomatic peripheral arterial disease in the CHARISMA trial | Journal of the American College of Cardiology | 2007 | 638 |
| Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis | Blood | 2003 | 635 |
| 2020 International Society of Hypertension Global Hypertension Practice Guidelines | Hypertension | 2020 | 628 |
| High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance | Blood | 2002 | 582 |
| A field guide to pandemic, epidemic and sporadic clones of methicillin-resistant Staphylococcus aureus | PLoS ONE | 2011 | 563 |
| Y-chromosomal diversity in Europe is clinal and influenced primarily by geography, rather than by language | American Journal of Human Genetics | 2000 | 471 |
| Aspirin resistance | Lancet, The | 2006 | 433 |
| Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment | European Heart Journal | 2015 | 430 |
| Familial hypercholesterolemia in the danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication | Journal of Clinical Endocrinology and Metabolism | 2012 | 412 |
| Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data | BMJ, The | 2014 | 406 |
| Improved analysis of brachial artery ultrasound using a novel edge-detection software system | Journal of Applied Physiology | 2001 | 403 |
| Anti-PCSK9 antibody effectively lowers cholesterol in patients with statin intolerance: the GAUSS-2 randomized, placebo-controlled phase 3 clinical trial of evolocumab | Journal of the American College of Cardiology | 2014 | 398 |
| Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R(2)CHADS(2) index in the ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation) and ATRIA (AnTicoagulation and Risk factors In Atrial fibrillation) study cohorts | Circulation | 2013 | 359 |
| The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management | Lancet Diabetes and Endocrinology,the | 2014 | 357 |
| Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial | Circulation | 2004 | 356 |
| SMART-COP: a tool for predicting the need for intensive respiratory or vasopressor support in community-acquired pneumonia | Clinical Infectious Diseases | 2008 | 351 |
| Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery | New England Journal of Medicine | 2018 | 349 |
| Treatment and secondary prevention of stroke: evidence, costs, and effects on individuals and populations | Lancet, The | 1999 | 349 |
| Neglecting legumes has compromised human health and sustainable food production | Nature Plants | 2016 | 344 |
| A population-based assessment of the impact and burden of caregiving for long-term stroke survivors | Stroke | 1995 | 341 |
