| # | Title | Journal | Year | Citations |
|---|
| 1 | Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor | New England Journal of Medicine | 1992 | 705 |
| 2 | Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease | Cell | 1995 | 673 |
| 3 | Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor | Nature | 1984 | 453 |
| 4 | Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor | New England Journal of Medicine | 1992 | 448 |
| 5 | Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage | Cell | 1987 | 377 |
| 6 | VEGF‐C and VEGF‐D expression in neuroendocrine cells and their receptor, VEGFR‐3, in fenestrated blood vessels in human tissues | FASEB Journal | 2000 | 299 |
| 7 | Ligand-induced Dimer-Tetramer Transition during the Activation of the Cell Surface Epidermal Growth Factor Receptor-A Multidimensional Microscopy Analysis | Journal of Biological Chemistry | 2005 | 232 |
| 8 | A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 199 |
| 9 | RING Finger Mutations that Abolish c-Cbl-Directed Polyubiquitination and Downregulation of the EGF Receptor Are Insufficient for Cell Transformation | Molecular Cell | 2001 | 164 |
| 10 | Mice lacking both macrophage- and granulocyte-macrophage colony- stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease | Blood | 1994 | 133 |
| 11 | Identical mRNA for preproglucagon in pancreas and gut | FEBS Journal | 1987 | 107 |
| 12 | Zebrafishstat3 is expressed in restricted tissues during embryogenesis andstat1 rescues cytokine signaling in aSTAT1-deficient human cell line | Developmental Dynamics | 1999 | 105 |
| 13 | Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages | Oncogene | 1992 | 104 |
| 14 | The zebrafish klf gene family | Blood | 2001 | 98 |
| 15 | Fas-mediated neutrophil apoptosis is accelerated by Bid, Bak, and Bax and inhibited by Bcl-2 and Mcl-1 | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 98 |
| 16 | Clonogenic growth of epithelial cells from normal colonic mucosa from both mice and humans | Gastroenterology | 1999 | 93 |
| 17 | Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro. | EMBO Journal | 1989 | 91 |
| 18 | The PI(3,5)P2 and PI(4,5)P2 Interactomes | Journal of Proteome Research | 2008 | 87 |
| 19 | Cortactin Overexpression Inhibits Ligand-Induced Down-regulation of the Epidermal Growth Factor Receptor | Cancer Research | 2005 | 77 |
| 20 | Lyn-Deficient Mice Develop Severe, Persistent Asthma: Lyn Is a Critical Negative Regulator of Th2 Immunity | Journal of Immunology | 2005 | 77 |
| 21 | Predominance of activated EGFR higher-order oligomers on the cell surface | Growth Factors | 2008 | 77 |
| 22 | Unligated Epidermal Growth Factor Receptor Forms Higher Order Oligomers within Microclusters on A431 Cells That Are Sensitive to Tyrosine Kinase Inhibitor Binding | Biochemistry | 2007 | 76 |
| 23 | Structural characterisation of native and recombinant forms of the neurotrophic cytokine MK | Journal of Chromatography A | 1993 | 71 |
| 24 | Gene Duplication of Zebrafish JAK2 Homologs Is Accompanied by Divergent Embryonic Expression Patterns: Only jak2a Is Expressed During Erythropoiesis | Blood | 1999 | 69 |
| 25 | Binding of gastrin(17) to human gastric carcinoma cell lines | Cancer Research | 1988 | 67 |
| 26 | Mice Lacking Three Myeloid Colony-Stimulating Factors (G-CSF, GM-CSF, and M-CSF) Still Produce Macrophages and Granulocytes and Mount an Inflammatory Response in a Sterile Model of Peritonitis | Journal of Immunology | 2007 | 62 |
| 27 | Synergies between micropreparative high-performance liquid chromatography and an instrumental optical biosensor | Journal of Chromatography A | 1994 | 58 |
| 28 | Measurement of gastrin and transforming growth factor alpha messenger RNA levels in colonic carcinoma cell lines by quantitative polymerase chain reaction | Cancer Research | 1992 | 58 |
| 29 | Synthesis and biological evaluation of phosphatidylinositol phosphate affinity probes | Organic and Biomolecular Chemistry | 2010 | 56 |
| 30 | Activation of c-myb by carboxy-terminal truncation: relationship to transformation of murine haemopoietic cells in vitro | EMBO Journal | 1989 | 51 |
| 31 | PI(3,4,5)P3 Interactome | Journal of Proteome Research | 2009 | 50 |
| 32 | Retention of tissue‐specific phenotype in a panel of colon carcinoma cell lines: Relationship to correlates | Immunology and Cell Biology | 1992 | 48 |
| 33 | Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1 | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 43 |
| 34 | The duplicitous nature of the Lyn tyrosine kinase in growth factor signaling | Growth Factors | 2006 | 42 |
| 35 | Plasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasites | Malaria Journal | 2015 | 42 |
| 36 | Lyn, a src-like tyrosine kinase | International Journal of Biochemistry and Cell Biology | 1997 | 41 |
| 37 | Micropreparative ligand fishing with a cuvette-based optical mirror resonance biosensor | Journal of Chromatography A | 2000 | 40 |
| 38 | Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling | Cell Death and Differentiation | 2009 | 40 |
| 39 | PCR cloning and sequence of gastrin mRNA from carcinoma cell lines | Biochemical and Biophysical Research Communications | 1990 | 37 |
| 40 | Analysis of the Binding of the Fab Fragment of Monoclonal Antibody NC10 to Influenza Virus N9 Neuraminidase from Tern and Whale Using the BIAcore Biosensor: Effect of Immobilization Level and Flow Rate on Kinetic Analysis | Analytical Biochemistry | 1999 | 36 |
| 41 | Murine fecal proteomics: A model system for the detection of potential biomarkers for colorectal cancer | Journal of Chromatography A | 2010 | 34 |
| 42 | Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases | Growth Factors | 2010 | 34 |
| 43 | Role of the 6‐20 disulfide bridge in the structure and activity of epidermal growth factor | Protein Science | 1998 | 33 |
| 44 | Mice lacking both macrophage- and granulocyte-macrophage colony-stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease | Blood | 1994 | 32 |
| 45 | Structural characterization of a murine myeloid leukaemia inhibitory factor | FEBS Journal | 1988 | 31 |
| 46 | Identification of a Ligand-binding Site on the Granulocyte Colony-stimulating Factor Receptor by Molecular Modeling and Mutagenesis | Journal of Biological Chemistry | 1997 | 31 |
| 47 | Functional evidence for human tumour suppressor genes: chromosome and molecular genetic studies | Cancer Surveys | 1992 | 31 |
| 48 | Therapy of Primary Diffuse Large Cell Lymphoma of the Penis with Preservation of Function | Journal of Urology | 1988 | 29 |
| 49 | Evidence for extended YFP-EGFR dimers in the absence of ligand on the surface of living cells | Physical Biology | 2011 | 27 |
| 50 | High rate of prolonged remissions following combined modality therapy for patients with localized low-grade lymphoma | Annals of Oncology | 1996 | 26 |
