# | Title | Journal | Year | Citations |
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1 | Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance | Advances in Immunology | 1999 | 998 |
2 | Fever and the thermal regulation of immunity: the immune system feels the heat | Nature Reviews Immunology | 2015 | 795 |
3 | Isolation and transmission of human retrovirus (human t-cell leukemia virus) | Science | 1983 | 577 |
4 | The mTOR Kinase Determines Effector versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin | Immunity | 2010 | 560 |
5 | The two faces of IL-6 in the tumor microenvironment | Seminars in Immunology | 2014 | 530 |
6 | Production of hepatitis B surface antigen in transgenic plants for oral immunization | Nature Biotechnology | 2000 | 446 |
7 | Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3β Inactivation | Science | 2008 | 414 |
8 | The regulation of immune tolerance by FOXP3 | Nature Reviews Immunology | 2017 | 398 |
9 | Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin | Cell | 2008 | 395 |
10 | Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpoints | Nature Communications | 2015 | 383 |
11 | Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation | European Journal of Immunology | 2003 | 338 |
12 | Role of cytokines in photodynamic therapy-induced local and systemic inflammation | British Journal of Cancer | 2003 | 308 |
13 | Oral immunization with hepatitis B surface antigen expressed in transgenic plants | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 303 |
14 | The virus of Japanese adult T-cell leukaemia is a member of the human T-cell leukaemia virus group | Nature | 1982 | 284 |
15 | Immunogenicity in humans of an edible vaccine for hepatitis B | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 282 |
16 | Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 260 |
17 | IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21 | Journal of Immunology | 2004 | 244 |
18 | Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation | Immunity | 2012 | 243 |
19 | Higher Frequencies of GARP+CTLA-4+Foxp3+ T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell Functionality | Cancer Research | 2013 | 231 |
20 | The maximal size of protein to diffuse through the nuclear pore is larger than 60 kDa | FEBS Letters | 2007 | 216 |
21 | Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism | PLoS ONE | 2011 | 199 |
22 | Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism | Nature Immunology | 2006 | 197 |
23 | IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells | Journal of Clinical Investigation | 2011 | 187 |
24 | Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells | Cancer Immunology, Immunotherapy | 2008 | 180 |
25 | Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry | Journal of Allergy and Clinical Immunology | 2018 | 172 |
26 | β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy | Cancer Research | 2017 | 168 |
27 | Human High Molecular Weight-Melanoma-Associated Antigen (HMW-MAA): A Melanoma Cell Surface Chondroitin Sulfate Proteoglycan (MSCP) with Biological and Clinical Significance | Critical Reviews in Immunology | 2004 | 167 |
28 | NADPH Oxidase Limits Innate Immune Responses in the Lungs in Mice | PLoS ONE | 2010 | 161 |
29 | Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma | Cancer Immunology, Immunotherapy | 2008 | 160 |
30 | Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models | PLoS ONE | 2012 | 158 |
31 | Contributions from Self-Renewal and Trafficking to the Uterine NK Cell Population of Early Pregnancy | Journal of Immunology | 2002 | 157 |
32 | Sustained antibody responses depend on CD28 function in bone marrow–resident plasma cells | Journal of Experimental Medicine | 2011 | 156 |
33 | Soluble human leukocyte antigen-G serum level is elevated in melanoma patients and is further increased by interferon-? immunotherapy | Cancer | 2001 | 155 |
34 | MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components | Molecular Immunology | 2008 | 155 |
35 | Lost in Translation: Obstacles to Translational Medicine | Journal of Translational Medicine | 2004 | 153 |
36 | β2-Microglobulin-Free HLA Class I Heavy Chain Epitope Mimicry by Monoclonal Antibody HC-10-Specific Peptide | Journal of Immunology | 2003 | 150 |
37 | Role of Antigen-Processing Machinery in the In Vitro Resistance of Squamous Cell Carcinoma of the Head and Neck Cells to Recognition by CTL | Journal of Immunology | 2006 | 144 |
38 | The Roman god Janus: a paradigm for the function of CD43 | Trends in Immunology | 1998 | 142 |
39 | Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermia | Journal of Cellular Physiology | 1998 | 140 |
40 | Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal | Immunological Reviews | 2016 | 140 |
41 | Enhancement of anti-tumor immunity by photodynamic therapy | Immunologic Research | 2010 | 139 |
42 | Immune Dysfunction in Patients with Chronic Obstructive Pulmonary Disease | Annals of the American Thoracic Society | 2015 | 139 |
43 | Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanisms | Journal of Cell Biology | 2004 | 133 |
44 | Smoking and Smokeless Tobacco-Associated Human Buccal Cell Mutations and Their Association with Oral Cancer--A Review | Cancer Epidemiology Biomarkers and Prevention | 2006 | 133 |
45 | CXCL12/CXCR4 Blockade by Oncolytic Virotherapy Inhibits Ovarian Cancer Growth by Decreasing Immunosuppression and Targeting Cancer-Initiating Cells | Journal of Immunology | 2014 | 132 |
46 | Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastases | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 129 |
47 | A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic response | Cancer Immunology, Immunotherapy | 2014 | 129 |
48 | Fever-range hyperthermia dynamically regulates lymphocyte delivery to high endothelial venules | Blood | 2001 | 125 |
49 | Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in mice | OncoImmunology | 2018 | 124 |
50 | Endoglin-Targeted Cancer Therapy | Current Drug Delivery | 2011 | 122 |