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Top Articles

#TitleJournalYearCitations
1Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional SignificanceAdvances in Immunology1999998
2Fever and the thermal regulation of immunity: the immune system feels the heatNature Reviews Immunology2015795
3Isolation and transmission of human retrovirus (human t-cell leukemia virus)Science1983577
4The mTOR Kinase Determines Effector versus Memory CD8+ T Cell Fate by Regulating the Expression of Transcription Factors T-bet and EomesoderminImmunity2010560
5The two faces of IL-6 in the tumor microenvironmentSeminars in Immunology2014530
6Production of hepatitis B surface antigen in transgenic plants for oral immunizationNature Biotechnology2000446
7Phosphorylation by p38 MAPK as an Alternative Pathway for GSK3β InactivationScience2008414
8The regulation of immune tolerance by FOXP3Nature Reviews Immunology2017398
9Systemic Endocrine Instigation of Indolent Tumor Growth Requires OsteopontinCell2008395
10Non-redundant requirement for CXCR3 signalling during tumoricidal T-cell trafficking across tumour vascular checkpointsNature Communications2015383
11Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligationEuropean Journal of Immunology2003338
12Role of cytokines in photodynamic therapy-induced local and systemic inflammationBritish Journal of Cancer2003308
13Oral immunization with hepatitis B surface antigen expressed in transgenic plantsProceedings of the National Academy of Sciences of the United States of America2001303
14The virus of Japanese adult T-cell leukaemia is a member of the human T-cell leukaemia virus groupNature1982284
15Immunogenicity in humans of an edible vaccine for hepatitis BProceedings of the National Academy of Sciences of the United States of America2005282
16Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperatureProceedings of the National Academy of Sciences of the United States of America2013260
17IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21Journal of Immunology2004244
18Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell DifferentiationImmunity2012243
19Higher Frequencies of GARP+CTLA-4+Foxp3+ T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell FunctionalityCancer Research2013231
20The maximal size of protein to diffuse through the nuclear pore is larger than 60 kDaFEBS Letters2007216
21Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent MechanismPLoS ONE2011199
22Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanismNature Immunology2006197
23IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cellsJournal of Clinical Investigation2011187
24Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cellsCancer Immunology, Immunotherapy2008180
25Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network RegistryJournal of Allergy and Clinical Immunology2018172
26β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor TherapyCancer Research2017168
27Human High Molecular Weight-Melanoma-Associated Antigen (HMW-MAA): A Melanoma Cell Surface Chondroitin Sulfate Proteoglycan (MSCP) with Biological and Clinical SignificanceCritical Reviews in Immunology2004167
28NADPH Oxidase Limits Innate Immune Responses in the Lungs in MicePLoS ONE2010161
29Association of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinomaCancer Immunology, Immunotherapy2008160
30Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer ModelsPLoS ONE2012158
31Contributions from Self-Renewal and Trafficking to the Uterine NK Cell Population of Early PregnancyJournal of Immunology2002157
32Sustained antibody responses depend on CD28 function in bone marrow–resident plasma cellsJournal of Experimental Medicine2011156
33Soluble human leukocyte antigen-G serum level is elevated in melanoma patients and is further increased by interferon-? immunotherapyCancer2001155
34MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery componentsMolecular Immunology2008155
35Lost in Translation: Obstacles to Translational MedicineJournal of Translational Medicine2004153
36β2-Microglobulin-Free HLA Class I Heavy Chain Epitope Mimicry by Monoclonal Antibody HC-10-Specific PeptideJournal of Immunology2003150
37Role of Antigen-Processing Machinery in the In Vitro Resistance of Squamous Cell Carcinoma of the Head and Neck Cells to Recognition by CTLJournal of Immunology2006144
38The Roman god Janus: a paradigm for the function of CD43Trends in Immunology1998142
39Tumor cell apoptosis, lymphocyte recruitment and tumor vascular changes are induced by low temperature, long duration (fever-like) whole body hyperthermiaJournal of Cellular Physiology1998140
40Neutrophils in the tumor microenvironment: trying to heal the wound that cannot healImmunological Reviews2016140
41Enhancement of anti-tumor immunity by photodynamic therapyImmunologic Research2010139
42Immune Dysfunction in Patients with Chronic Obstructive Pulmonary DiseaseAnnals of the American Thoracic Society2015139
43Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanismsJournal of Cell Biology2004133
44Smoking and Smokeless Tobacco-Associated Human Buccal Cell Mutations and Their Association with Oral Cancer--A ReviewCancer Epidemiology Biomarkers and Prevention2006133
45CXCL12/CXCR4 Blockade by Oncolytic Virotherapy Inhibits Ovarian Cancer Growth by Decreasing Immunosuppression and Targeting Cancer-Initiating CellsJournal of Immunology2014132
46Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastasesProceedings of the National Academy of Sciences of the United States of America2013129
47A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic responseCancer Immunology, Immunotherapy2014129
48Fever-range hyperthermia dynamically regulates lymphocyte delivery to high endothelial venulesBlood2001125
49Beta blocker use correlates with better overall survival in metastatic melanoma patients and improves the efficacy of immunotherapies in miceOncoImmunology2018124
50Endoglin-Targeted Cancer TherapyCurrent Drug Delivery2011122