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exaly
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Department of Pharmacology
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top-articles
Department of Pharmacology
309
(top 1%)
papers
17.8K
(top 1%)
citations
72
(top 1%)
h
-index
117
(top 1%)
g
-index
324
all documents
18.7K
doc citations
2.5K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
DNA Topoisomerases: Essential Enzymes and Lethal Targets
Annual Review of Pharmacology and Toxicology
1994
704
2
TUMORCELLDEATHINDUCED BYTOPOISOMERASE-TARGETINGDRUGS
Annual Review of Pharmacology and Toxicology
2001
499
3
Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans
Cell
1990
417
4
Mechanism of Action of Camptothecin
Annals of the New York Academy of Sciences
2000
383
5
Role of Autophagy in Cancer: Management of Metabolic Stress
Autophagy
2007
367
6
Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans.
Proceedings of the National Academy of Sciences of the United States of America
1994
352
7
NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.
Molecular Biology of the Cell
1995
340
8
mTORC1-mediated translational elongation limits intestinal tumour initiation and growth
Nature
2015
257
9
Nucleosomes Can Form a Polar Barrier to Transcript Elongation by RNA Polymerase II
Molecular Cell
2006
248
10
Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a γ-actin
Gene
1988
223
11
Three-Dimensional Nanofibrillar Surfaces Promote Self-Renewal in Mouse Embryonic Stem Cells
Stem Cells
2006
221
12
Ubiquitin-dependent Destruction of Topoisomerase I Is Stimulated by the Antitumor Drug Camptothecin
Journal of Biological Chemistry
1997
220
13
l
‐DOPA Cytotoxicity to PC12 Cells in Culture Is via Its Autoxidation
Journal of Neurochemistry
1995
201
14
Calcium-Dependent Regulation of Protein Synthesis in Intact Mammalian Cells
Annual Review of Physiology
1990
199
15
Mechanism of Action of Camptothecin
Annals of the New York Academy of Sciences
1996
193
16
Aminoguanidine Is an Isoform-Selective, Mechanism-Based Inactivator of Nitric Oxide Synthase
Archives of Biochemistry and Biophysics
1995
187
17
Phosphorylation of Annexin I by TRPM7 Channel-Kinase
Journal of Biological Chemistry
2004
183
18
Calcium dynamics and endoplasmic reticular function in the regulation of protein synthesis: implications for cell growth and adaptability
Cell Calcium
2003
182
19
Nuclear Migration
Journal of Cell Biology
2000
176
20
Sealing cultured invertebrate neurons to embedded dish electrodes facilitates long-term stimulation and recording
Journal of Neuroscience Methods
1989
174
21
Elevated Expression of ISG15 in Tumor Cells Interferes with the Ubiquitin/26S Proteasome Pathway
Cancer Research
2006
171
22
Targeting the mTOR kinase domain: the second generation of mTOR inhibitors
Drug Discovery Today
2011
170
23
Sir-Mediated Repression Can Occur Independently of Chromosomal and Subnuclear Contexts
Cell
2004
168
24
Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells
Cancer Research
2001
167
25
Characterization of the Protein Kinase Activity of TRPM7/ChaK1, a Protein Kinase Fused to the Transient Receptor Potential Ion Channel
Journal of Biological Chemistry
2004
164
26
Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation
PLoS ONE
2008
164
27
The Lis1-Related Nudf Protein of Aspergillus nidulans Interacts with the Coiled-Coil Domain of the Nude/Ro11 Protein
Journal of Cell Biology
2000
163
28
Role of Topoisomerase IIβ in the Expression of Developmentally RegulatedGenes
Molecular and Cellular Biology
2006
162
29
Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the Lung
PLoS Pathogens
2014
154
30
Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells
Biochemical Journal
1993
152
31
Processing of topoisomerase I cleavable complexes into DNA damage by transcription
Nucleic Acids Research
1997
152
32
Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans.
Journal of Cell Biology
1993
139
33
Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest
Journal of Cell Science
2002
139
34
Hypernegative supercoiling of the DNA template during transcription elongation in vitro.
Journal of Biological Chemistry
1994
134
35
Transcription-Dependent Degradation of Topoisomerase I-DNA Covalent Complexes
Molecular and Cellular Biology
2003
127
36
Autophagy and the degradation of mitochondria
Mitochondrion
2010
124
37
Mechanism of transcription through a nucleosome by RNA polymerase II
Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms
2013
121
38
Fluorescence-Based Approach for Detecting and Characterizing Antibiotic-Induced Conformational Changes in Ribosomal RNA: Comparing Aminoglycoside Binding to Prokaryotic and Eukaryotic Ribosomal RNA Sequences
Journal of the American Chemical Society
2004
119
39
Living in Three Dimensions: 3D Nanostructured Environments for Cell Culture and Regenerative Medicine
Cell Biochemistry and Biophysics
2006
116
40
Minor Groove-Directed and Intercalative Ligand−DNA Interactions in the Poisoning of Human DNA Topoisomerase I by Protoberberine Analogs†
Biochemistry
1997
115
41
Alpha-kinases: analysis of the family and comparison with conventional protein kinases
Progress in Biophysics and Molecular Biology
2004
115
42
Phosphorylation of eukaryotic initiation factor (eIF) 2 alpha and inhibition of eIF-2B in GH3 pituitary cells by perturbants of early protein processing that induce GRP78.
Journal of Biological Chemistry
1992
115
43
Distant Activation of Transcription: Mechanisms of Enhancer Action
Molecular and Cellular Biology
2012
109
44
Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside
Journal of Neurochemistry
2001
100
45
Dyneins Have Run Their Course in Plant Lineage
Traffic
2001
100
46
Dissection of astrocyte-mediated cues in neuronal guidance and process extension
1999
99
47
Translation Elongation Factor 2 Anticodon Mimicry Domain Mutants Affect Fidelity and Diphtheria Toxin Resistance
Journal of Biological Chemistry
2006
99
48
Yeast heterochromatin is a dynamic structure that requires silencers continuously
Genes and Development
2000
99
49
The Inhibition of the Constitutive and Inducible Nitric-Oxide Synthase Isoforms by Indazole Agents
Archives of Biochemistry and Biophysics
1994
98
50
Phosphorylation of eukaryotic initiation factor (eIF) 2 alpha and inhibition of eIF-2B in GH3 pituitary cells by perturbants of early protein processing that induce GRP78
Journal of Biological Chemistry
1992
98
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