309(top 1%)
papers
17.8K(top 1%)
citations
72(top 1%)
h-index
117(top 1%)
g-index
324
all documents
18.7K
doc citations
2.5K
citing journals

Top Articles

#TitleJournalYearCitations
1DNA Topoisomerases: Essential Enzymes and Lethal TargetsAnnual Review of Pharmacology and Toxicology1994704
2TUMORCELLDEATHINDUCED BYTOPOISOMERASE-TARGETINGDRUGSAnnual Review of Pharmacology and Toxicology2001499
3Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulansCell1990417
4Mechanism of Action of CamptothecinAnnals of the New York Academy of Sciences2000383
5Role of Autophagy in Cancer: Management of Metabolic StressAutophagy2007367
6Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans.Proceedings of the National Academy of Sciences of the United States of America1994352
7NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration.Molecular Biology of the Cell1995340
8mTORC1-mediated translational elongation limits intestinal tumour initiation and growthNature2015257
9Nucleosomes Can Form a Polar Barrier to Transcript Elongation by RNA Polymerase IIMolecular Cell2006248
10Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a γ-actinGene1988223
11Three-Dimensional Nanofibrillar Surfaces Promote Self-Renewal in Mouse Embryonic Stem CellsStem Cells2006221
12Ubiquitin-dependent Destruction of Topoisomerase I Is Stimulated by the Antitumor Drug CamptothecinJournal of Biological Chemistry1997220
13l‐DOPA Cytotoxicity to PC12 Cells in Culture Is via Its AutoxidationJournal of Neurochemistry1995201
14Calcium-Dependent Regulation of Protein Synthesis in Intact Mammalian CellsAnnual Review of Physiology1990199
15Mechanism of Action of CamptothecinAnnals of the New York Academy of Sciences1996193
16Aminoguanidine Is an Isoform-Selective, Mechanism-Based Inactivator of Nitric Oxide SynthaseArchives of Biochemistry and Biophysics1995187
17Phosphorylation of Annexin I by TRPM7 Channel-KinaseJournal of Biological Chemistry2004183
18Calcium dynamics and endoplasmic reticular function in the regulation of protein synthesis: implications for cell growth and adaptabilityCell Calcium2003182
19Nuclear MigrationJournal of Cell Biology2000176
20Sealing cultured invertebrate neurons to embedded dish electrodes facilitates long-term stimulation and recordingJournal of Neuroscience Methods1989174
21Elevated Expression of ISG15 in Tumor Cells Interferes with the Ubiquitin/26S Proteasome PathwayCancer Research2006171
22Targeting the mTOR kinase domain: the second generation of mTOR inhibitorsDrug Discovery Today2011170
23Sir-Mediated Repression Can Occur Independently of Chromosomal and Subnuclear ContextsCell2004168
24Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cellsCancer Research2001167
25Characterization of the Protein Kinase Activity of TRPM7/ChaK1, a Protein Kinase Fused to the Transient Receptor Potential Ion ChannelJournal of Biological Chemistry2004164
26Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK ActivationPLoS ONE2008164
27The Lis1-Related Nudf Protein of Aspergillus nidulans Interacts with the Coiled-Coil Domain of the Nude/Ro11 ProteinJournal of Cell Biology2000163
28Role of Topoisomerase IIβ in the Expression of Developmentally RegulatedGenesMolecular and Cellular Biology2006162
29Inflammatory Monocytes Orchestrate Innate Antifungal Immunity in the LungPLoS Pathogens2014154
30Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cellsBiochemical Journal1993152
31Processing of topoisomerase I cleavable complexes into DNA damage by transcriptionNucleic Acids Research1997152
32Suppression of the bimC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans.Journal of Cell Biology1993139
33Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrestJournal of Cell Science2002139
34Hypernegative supercoiling of the DNA template during transcription elongation in vitro.Journal of Biological Chemistry1994134
35Transcription-Dependent Degradation of Topoisomerase I-DNA Covalent ComplexesMolecular and Cellular Biology2003127
36Autophagy and the degradation of mitochondriaMitochondrion2010124
37Mechanism of transcription through a nucleosome by RNA polymerase IIBiochimica Et Biophysica Acta - Gene Regulatory Mechanisms2013121
38Fluorescence-Based Approach for Detecting and Characterizing Antibiotic-Induced Conformational Changes in Ribosomal RNA:  Comparing Aminoglycoside Binding to Prokaryotic and Eukaryotic Ribosomal RNA SequencesJournal of the American Chemical Society2004119
39Living in Three Dimensions: 3D Nanostructured Environments for Cell Culture and Regenerative MedicineCell Biochemistry and Biophysics2006116
40Minor Groove-Directed and Intercalative Ligand−DNA Interactions in the Poisoning of Human DNA Topoisomerase I by Protoberberine Analogs†Biochemistry1997115
41Alpha-kinases: analysis of the family and comparison with conventional protein kinasesProgress in Biophysics and Molecular Biology2004115
42Phosphorylation of eukaryotic initiation factor (eIF) 2 alpha and inhibition of eIF-2B in GH3 pituitary cells by perturbants of early protein processing that induce GRP78.Journal of Biological Chemistry1992115
43Distant Activation of Transcription: Mechanisms of Enhancer ActionMolecular and Cellular Biology2012109
44Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinosideJournal of Neurochemistry2001100
45Dyneins Have Run Their Course in Plant LineageTraffic2001100
46Dissection of astrocyte-mediated cues in neuronal guidance and process extension199999
47Translation Elongation Factor 2 Anticodon Mimicry Domain Mutants Affect Fidelity and Diphtheria Toxin ResistanceJournal of Biological Chemistry200699
48Yeast heterochromatin is a dynamic structure that requires silencers continuouslyGenes and Development200099
49The Inhibition of the Constitutive and Inducible Nitric-Oxide Synthase Isoforms by Indazole AgentsArchives of Biochemistry and Biophysics199498
50Phosphorylation of eukaryotic initiation factor (eIF) 2 alpha and inhibition of eIF-2B in GH3 pituitary cells by perturbants of early protein processing that induce GRP78Journal of Biological Chemistry199298