| # | Title | Journal | Year | Citations |
|---|
| 1 | Angiographic quantitative flow ratio-guided coronary intervention (FAVOR III China): a multicentre, randomised, sham-controlled trial | Lancet, The | 2021 | 175 |
| 2 | Insights Into Echo-Attenuated Plaques, Echolucent Plaques, and Plaques With Spotty Calcification | Journal of the American College of Cardiology | 2014 | 170 |
| 3 | Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury | European Heart Journal | 2013 | 163 |
| 4 | The ubiquitin E3 ligase TRAF6 exacerbates pathological cardiac hypertrophy via TAK1-dependent signalling | Nature Communications | 2016 | 143 |
| 5 | Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design | Nature Communications | 2021 | 124 |
| 6 | STABLE-SR (Electrophysiological Substrate Ablation in the Left Atrium During Sinus Rhythm) for the Treatment of Nonparoxysmal Atrial Fibrillation | Circulation: Arrhythmia and Electrophysiology | 2017 | 119 |
| 7 | Clinical Adverse Effects of Endothelin Receptor Antagonists: Insights From the Meta‐Analysis of 4894 Patients From 24 Randomized Double‐Blind Placebo‐Controlled Clinical Trials | Journal of the American Heart Association | 2016 | 92 |
| 8 | Discovery of cryptic allosteric sites using reversed allosteric communication by a combined computational and experimental strategy | Chemical Science | 2021 | 84 |
| 9 | Atorvastatin Inhibits Inflammatory Response, Attenuates Lipid Deposition, and Improves the Stability of Vulnerable Atherosclerotic Plaques by Modulating Autophagy | Frontiers in Pharmacology | 2018 | 75 |
| 10 | Angiogenesis by transplantation of HIF-1α modified EPCs into ischemic limbs | Journal of Cellular Biochemistry | 2008 | 74 |
| 11 | Efficacy and Safety of a Pharmaco-Invasive Strategy With Half-Dose Alteplase Versus Primary Angioplasty in ST-Segment–Elevation Myocardial Infarction | Circulation | 2017 | 73 |
| 12 | Emergence of allosteric drug-resistance mutations: new challenges for allosteric drug discovery | Drug Discovery Today | 2020 | 67 |
| 13 | Feasibility of using deep learning to detect coronary artery disease based on facial photo | European Heart Journal | 2020 | 67 |
| 14 | Effects of Resveratrol on Endothelial Progenitor Cells and Their Contributions to Reendothelialization in Intima-injured Rats | Journal of Cardiovascular Pharmacology | 2006 | 66 |
| 15 | Resveratrol inhibits EMMPRIN expression via P38 and ERK1/2 pathways in PMA-induced THP-1 cells | Biochemical and Biophysical Research Communications | 2008 | 62 |
| 16 | Suppressor of IKKɛ is an essential negative regulator of pathological cardiac hypertrophy | Nature Communications | 2016 | 60 |
| 17 | Beneficial effects of catheter ablation of frequent premature ventricular complexes on left ventricular function | Heart | 2014 | 57 |
| 18 | MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways | Experimental and Molecular Medicine | 2018 | 56 |
| 19 | Non-vitamin K Antagonist Oral Anticoagulants vs. Warfarin at Risk of Fractures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Frontiers in Pharmacology | 2018 | 55 |
| 20 | Risk of Major Gastrointestinal Bleeding With New vs Conventional Oral Anticoagulants: A Systematic Review and Meta-analysis | Clinical Gastroenterology and Hepatology | 2020 | 54 |
| 21 | Atorvastatin Improves Plaque Stability in ApoE-Knockout Mice by Regulating Chemokines and Chemokine Receptors | PLoS ONE | 2014 | 53 |
| 22 | Mechanistic insights into the effect of phosphorylation on Ras conformational dynamics and its interactions with cell signaling proteins | Computational and Structural Biotechnology Journal | 2021 | 51 |
| 23 | Endogenous Renovascular Hypertension Combined With Low Shear Stress Induces Plaque Rupture in Apolipoprotein E–Deficient Mice | Arteriosclerosis, Thrombosis, and Vascular Biology | 2012 | 47 |
| 24 | In vivo enhancement of angiogenesis by adenoviral transfer of HIF-1α-modified endothelial progenitor cells (Ad-HIF-1α-modified EPC for angiogenesis) | International Journal of Biochemistry and Cell Biology | 2008 | 42 |
| 25 | TBX20 loss-of-function mutation associated with familial dilated cardiomyopathy | Clinical Chemistry and Laboratory Medicine | 2016 | 42 |
| 26 | RXR agonists inhibit oxidative stress-induced apoptosis in H9c2 rat ventricular cells | Biochemical and Biophysical Research Communications | 2008 | 40 |
| 27 | Rational transplant timing and dose of mesenchymal stromal cells in patients with acute myocardial infarction: a meta-analysis of randomized controlled trials | Stem Cell Research and Therapy | 2017 | 40 |
| 28 | Incidence of Venous Thromboembolism in Hospitalized Coronavirus Disease 2019 Patients: A Systematic Review and Meta-Analysis | Frontiers in Cardiovascular Medicine | 2020 | 39 |
| 29 | TIMI myocardial perfusion frame count: A new method to assess myocardial perfusion and its predictive value for short‐term prognosis | Catheterization and Cardiovascular Interventions | 2010 | 38 |
| 30 | Iron deficiency activates pro-inflammatory signaling in macrophages and foam cells via the p38 MAPK-NF-κB pathway | International Journal of Cardiology | 2011 | 38 |
| 31 | The cannabinoid WIN55,212-2 protects against oxidized LDL-induced inflammatory response in murine macrophages | Journal of Lipid Research | 2010 | 37 |
| 32 | A retrospective study on the aetiology, management, and outcome of brain abscess in an 11-year, single-centre study from China | BMC Infectious Diseases | 2014 | 35 |
| 33 | MFGE8 attenuates Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation through inhibition of TGF-β1/Smad2/3 pathway | Journal of Molecular and Cellular Cardiology | 2020 | 35 |
| 34 | Peroxisome proliferator-activated receptor γ (PPARγ) mediates the protective effect of quercetin against myocardial ischemia-reperfusion injury via suppressing the NF-κB pathway | American Journal of Translational Research (discontinued) | 2016 | 35 |
| 35 | Retinoid X receptor agonists inhibit phorbol-12-myristate-13-acetate (PMA)-induced differentiation of monocytic THP-1 cells into macrophages | Molecular and Cellular Biochemistry | 2010 | 34 |
| 36 | AMPK activation attenuates inflammatory response to reduce ambient PM2.5-induced metabolic disorders in healthy and diabetic mice | Ecotoxicology and Environmental Safety | 2019 | 34 |
| 37 | Maximum Efficacy of Mesenchymal Stem Cells in Rat Model of Renal Ischemia-Reperfusion Injury: Renal Artery Administration with Optimal Numbers | PLoS ONE | 2014 | 34 |
| 38 | A SHOX2 loss-of-function mutation underlying familial atrial fibrillation | International Journal of Medical Sciences | 2018 | 33 |
| 39 | Three-Dimensional Tricuspid Annular Motion Analysis from Cardiac Magnetic Resonance Feature-Tracking | Annals of Biomedical Engineering | 2016 | 32 |
| 40 | Inhibition of Hypoxia-Inducible Factor-1α and Endothelial Progenitor Cell Differentiation by Adenoviral Transfer of Small Interfering RNA in vitro | Journal of Vascular Research | 2006 | 31 |
| 41 | Real-World Prevalence of Direct Oral Anticoagulant Off-Label Doses in Atrial Fibrillation: An Epidemiological Meta-Analysis | Frontiers in Pharmacology | 2021 | 31 |
| 42 | A novel individualized substrate modification approach for the treatment of long-standing persistent atrial fibrillation: Preliminary results | International Journal of Cardiology | 2014 | 29 |
| 43 | A Dual Targeting Drug Delivery System for Penetrating Blood-Brain Barrier and Selectively Delivering siRNA to Neurons for Alzheimer’s Disease Treatment | Current Pharmaceutical Biotechnology | 2018 | 29 |
| 44 | Effects of Testosterone on Cytokines and Left Ventricular Remodeling Following Heart Failure | Cellular Physiology and Biochemistry | 2007 | 28 |
| 45 | Natriuretic Peptides as an Adjunctive Treatment for Acute Myocardial Infarction | International Heart Journal | 2014 | 27 |
| 46 | Non-vitamin K Antagonist Oral Anticoagulants and Cognitive Impairment in Atrial Fibrillation: Insights From the Meta-Analysis of Over 90,000 Patients of Randomized Controlled Trials and Real-World Studies | Frontiers in Aging Neuroscience | 2018 | 27 |
| 47 | The Value of ECG Lead aVR in the Differential Diagnosis of Acute Inferior Wall Myocardial Infarction | Internal Medicine | 2007 | 26 |
| 48 | Increased risk of myocardial infarction with dabigatran etexilate: fact or fiction? A critical meta-analysis of over 580,000 patients from integrating randomized controlled trials and real-world studies | International Journal of Cardiology | 2018 | 26 |
| 49 | Computational methods-guided design of modulators targeting protein-protein interactions (PPIs) | European Journal of Medicinal Chemistry | 2020 | 26 |
| 50 | Farnesoid X receptor knockout protects brain against ischemic injury through reducing neuronal apoptosis in mice | Journal of Neuroinflammation | 2020 | 26 |
