| # | Title | Journal | Year | Citations |
|---|
| 1 | Blood pressure, stroke, and coronary heart disease *1Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias | Lancet, The | 1990 | 4,062 |
| 2 | Underestimation of Risk Associations Due to Regression Dilution in Long-term Follow-up of Prospective Studies | American Journal of Epidemiology | 1999 | 706 |
| 3 | INTENSIVE INTRAVENOUS REGIMEN FOR SEVERE ATTACKS OF ULCERATIVE COLITIS | Lancet, The | 1974 | 488 |
| 4 | Linkage of type 2 diabetes to the glucokinase gene | Lancet, The | 1992 | 392 |
| 5 | Separation of viable schizont-infected red cells ofPlasmodium falciparumfrom human blood | Annals of Tropical Medicine and Parasitology | 1978 | 342 |
| 6 | Reliable assessment of the effects of treatment on mortality and major morbidity, I: clinical trials | Lancet, The | 2001 | 297 |
| 7 | Assembly and secretion of hepatic very-low-density lipoprotein | Biochemical Journal | 1990 | 291 |
| 8 | Effects of foetal haemoglobin on susceptibility of red cells to Plasmodium falciparum | Nature | 1977 | 171 |
| 9 | Comparison of tests of beta-cell function across a range of glucose tolerance from normal to diabetes | Diabetes | 1999 | 170 |
| 10 | Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: a detailed dose-response study | Cancer Research | 1991 | 132 |
| 11 | Short- and longer-term regulation of very-low-density lipoprotein secretion by insulin, dexamethasone and lipogenic substrates in cultured hepatocytes. A biphasic effect of insulin | Biochemical Journal | 1988 | 129 |
| 12 | Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes | Biochemical Journal | 1992 | 114 |
| 13 | FETAL HqMOGLOBIN AND MALARIA | Lancet, The | 1976 | 106 |
| 14 | ABNORMALITIES IN THE APPARENTLY NORMAL BOWEL MUCOSA IN CROHN'S DISEASE | Lancet, The | 1976 | 101 |
| 15 | THE EXPERIMENTAL PRODUCTION OF MACROCYTIC ANEMIA BY OPERATIONS ON THE INTESTINAL TRACT | Blood | 1949 | 100 |
| 16 | Dose and time relationships for tumor induction in the liver and esophagus of 4080 inbred rats by chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine | Cancer Research | 1991 | 96 |
| 17 | The metabolic effects of sodium dichloroacetate in the starved rat | Biochemical Journal | 1974 | 93 |
| 18 | AUTOANTIBODIES TO RETICULIN IN PATIENTS WITH IDIOPATHIC STEATORRHŒA, CŒLIAC DISEASE, AND CROHN'S DISEASE, AND THEIR RELATION TO IMMUNOGLOBULINS AND DIETARY ANTIBODIES | Lancet, The | 1971 | 92 |
| 19 | DIABETES: THE QUEST FOR BASAL NORMOGLYCÆMIA | Lancet, The | 1977 | 88 |
| 20 | Uptake of individual fatty acids into adipose tissue in relation to their presence in the diet | American Journal of Clinical Nutrition | 2000 | 88 |
| 21 | Three-year follow-up of the Oxford Cholesterol Study: assessment of the efficacy and safety of simvastatin in preparation for a large mortality study | European Heart Journal | 1994 | 85 |
| 22 | Release of individual fatty acids from human adipose tissue in vivo after an overnight fast | Journal of Lipid Research | 1996 | 81 |
| 23 | Plasma proinsulin, C-peptide and insulin in diagnostic suppression tests for insulinomas | Diabetologia | 1977 | 80 |
| 24 | Sulphonylurea Failure in Type 2 Diabetes: Treatment with a Basal Insulin Supplement | Diabetic Medicine | 1987 | 79 |
| 25 | Regulation of fatty acid movement in human adipose tissue in the postabsorptive-to-postprandial transition | American Journal of Physiology - Endocrinology and Metabolism | 1994 | 79 |
| 26 | Insulin Inhibits the Maturation Phase of VLDL Assembly via a Phosphoinositide 3-Kinase—Mediated Event | Arteriosclerosis, Thrombosis, and Vascular Biology | 2001 | 79 |
| 27 | A MODEL FOR THE PERSISTENCE OR REACTIVATION OF FETAL HqMOGLOBIN PRODUCTION | Lancet, The | 1976 | 76 |
| 28 | The Study of Erythropoiesis Using Tracer Quantities of Radioactive Iron | British Journal of Haematology | 1956 | 73 |
| 29 | The UK Prospective Diabetes study | Lancet, The | 1998 | 71 |
| 30 | Inhibition of lymphocyte recirculation by stress and corticotropin | Cellular Immunology | 1972 | 63 |
| 31 | The Hypertension in the Very Elderly Trial (HYVET) | Drugs and Aging | 1994 | 61 |
| 32 | Effects of epinephrine infusion on adipose tissue: interactions between blood flow and lipid metabolism | American Journal of Physiology - Endocrinology and Metabolism | 1996 | 60 |
| 33 | AUSTRALIA ANTIGEN AND SMOOTH-MUSCLE ANTIBODY IN ACUTE AND CHRONIC HEPATITIS | Lancet, The | 1970 | 59 |
| 34 | Release of individual fatty acids from human adipose tissue in vivo after an overnight fast | Journal of Lipid Research | 1996 | 59 |
| 35 | LYMPHOCYTE-DEPENDENT CYTOTOXIC ANTIBODY ACTIVITY AGAINST HUMAN TRANSPLANTATION ANTIGENS | Transplantation | 1973 | 56 |
| 36 | Storage, mobilization and secretion of cytosolic triacylglycerol in hepatocyte cultures. The role of insulin | Biochemical Journal | 1990 | 56 |
| 37 | Secretion and storage of newly synthesized hepatic triacylglycerol fatty acids in vivo in different nutritional states and in diabetes | Biochemical Journal | 1988 | 55 |
| 38 | A direct estimate of the number of human γ-globin genes | Cell | 1976 | 53 |
| 39 | Antihypertensive drug treatment. Potential, expected, and observed effects on stroke and on coronary heart disease. | Hypertension | 1989 | 53 |
| 40 | Comparative effects of tumour necrosis factor-α (cachectin), interleukin-1-β and tumour growth on amino acid metabolism in the rat in vivo. Absorption and tissue uptake of α-amino[1-14C]isobutyrate | Biochemical Journal | 1989 | 52 |
| 41 | Chronic nitrosamine ingestion in 1040 rodents: the effect of the choice of nitrosamine, the species studied, and the age of starting exposure | Cancer Research | 1991 | 52 |
| 42 | INSULIN RATHER THAN GLUCOSE HOM$OElig;OSTASIS IN THE PATHOPHYSIOLOGY OF DIABETES | Lancet, The | 1976 | 50 |
| 43 | Long-term maintenance of high rates of very-low-density-lipoprotein secretion in hepatocyte cultures. A model for studying the direct effects of insulin and insulin deficiency in vitro | Biochemical Journal | 1989 | 49 |
| 44 | THE CLINICAL ASSOCIATION OF MACROCYTIC ANEMIA WITH INTESTINAL STRICTURE AND ANASTOMOSIS | Blood | 1949 | 48 |
| 45 | STIMULATION OF LYMPHOCYTES FROM PATIENTS WITH CŒLIAC DISEASE BY A SUBFRACTION OF GLUTEN | Lancet, The | 1976 | 48 |
| 46 | The portal circulation in experimental cirrhosis of the liver | The Journal of Pathology and Bacteriology | 1952 | 47 |
| 47 | Haemoglobin J Tongariki is associated with α thalassaemia | Nature | 1978 | 47 |
| 48 | SUPPRESSION OF INSULIN RELEASE BY FISH-INSULIN-INDUCED HYPOGLYCÆMIA WITH REFERENCE TO THE DIAGNOSIS OF INSULINOMAS | Lancet, The | 1973 | 45 |
| 49 | Basal normoglycemia attained with chlorpropamide in mild diabetes | Metabolism: Clinical and Experimental | 1978 | 43 |
| 50 | Tumour necrosis factor α (cachectin) mimics some of the effects of tumour growth on the disposal of a [14C]lipid load in virgin, lactating and litter-removed rats | Biochemical Journal | 1988 | 42 |
