IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses | Journal of Experimental Medicine | 2010 | 562 |
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 413 |
Extracellular adenosine triphosphate and adenosine in cancer | Oncogene | 2010 | 410 |
Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma | Leukemia | 2010 | 404 |
The structural basis for membrane binding and pore formation by lymphocyte perforin | Nature | 2010 | 289 |
Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity | Cancer Research | 2010 | 244 |
Innate immunity defines the capacity of antiviral T cells to limit persistent infection | Journal of Experimental Medicine | 2010 | 171 |
Chemotherapy and radiotherapy: cryptic anticancer vaccines | Seminars in Immunology | 2010 | 164 |
Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth | Cancer Research | 2010 | 153 |
Perforin: structure, function, and role in human immunopathology | Immunological Reviews | 2010 | 136 |
DNAM-1/CD155 interactions promote cytokine and NK cell-mediated suppression of poorly immunogenic melanoma metastases | Journal of Immunology | 2010 | 134 |
Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma | Blood | 2010 | 121 |
Functional dissection of the granzyme family: cell death and inflammation | Immunological Reviews | 2010 | 104 |
Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms | Journal of Immunology | 2010 | 94 |
Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis Y antigen | Gene Therapy | 2010 | 83 |
The role of perforin and granzymes in diabetes | Cell Death and Differentiation | 2010 | 72 |
Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules | Journal of Immunology | 2010 | 70 |
A role for granzyme M in TLR4-driven inflammation and endotoxicosis | Journal of Immunology | 2010 | 69 |
Multiple antitumor mechanisms downstream of prophylactic regulatory T-cell depletion | Cancer Research | 2010 | 62 |
The structure and function of mammalian membrane-attack complex/perforin-like proteins | Tissue Antigens | 2010 | 54 |
The battlefield of perforin/granzyme cell death pathways | Journal of Leukocyte Biology | 2010 | 52 |
CD11c+ dendritic cells and B cells contribute to the tumoricidal activity of anti-DR5 antibody therapy in established tumors | Journal of Immunology | 2010 | 48 |
Tumor ablation by gene-modified T cells in the absence of autoimmunity | Cancer Research | 2010 | 46 |
Perforin deficiency and susceptibility to cancer | Cell Death and Differentiation | 2010 | 45 |
Human and mouse perforin are processed in part through cleavage by the lysosomal cysteine proteinase cathepsin L | Immunology | 2010 | 37 |