217(top 1%)
papers
12.6K(top 1%)
citations
62(top 1%)
h-index
105(top 1%)
g-index
228
all documents
13.1K
doc citations
2.0K
citing journals

Top Articles

#TitleJournalYearCitations
1Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeineNature Neuroscience2005576
2Arousal effect of orexin A depends on activation of the histaminergic systemProceedings of the National Academy of Sciences of the United States of America2001514
3Enzymes of the Cyclooxygenase Pathways of Prostanoid BiosynthesisChemical Reviews2011410
4A toxic monomeric conformer of the polyglutamine proteinNature Structural and Molecular Biology2007296
5Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthaseBBA - Proteins and Proteomics2000290
6Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus AccumbensJournal of Neuroscience2011267
7Prostaglandin D synthase: Structure and functionVitamins and Hormones2000261
8miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppressionNature Neuroscience2011252
9Circadian Dynamics of Cytosolic and Nuclear Ca2+ in Single Suprachiasmatic Nucleus NeuronsNeuron2003250
10Cloning and Crystal Structure of Hematopoietic Prostaglandin D SynthaseCell1997244
11Dopaminergic D1and D2Receptors Are Essential for the Arousal Effect of ModafinilJournal of Neuroscience2008220
12Pronounced Eosinophilic Lung Inflammation and Th2 Cytokine Release in Human Lipocalin-Type Prostaglandin D Synthase Transgenic MiceJournal of Immunology2002212
13Prostaglandins and adenosine in the regulation of sleep and wakefulnessCurrent Opinion in Pharmacology2007206
14Silica Crystals and Aluminum Salts Regulate the Production of Prostaglandin in Macrophages via NALP3 Inflammasome-Independent MechanismsImmunity2011199
15Prostaglandin D2 Plays an Essential Role in Chronic Allergic Inflammation of the Skin via CRTH2 ReceptorJournal of Immunology2006188
16Prostaglandin D2 and sleep/wake regulationSleep Medicine Reviews2011176
17The Role of Adenosine in the Regulation of SleepCurrent Topics in Medicinal Chemistry2011175
18Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout miceProceedings of the National Academy of Sciences of the United States of America2006171
19Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergenceProstaglandins and Other Lipid Mediators2002169
20An adenosine A2A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in ratsJournal of Neurochemistry2005139
21Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluidProceedings of the National Academy of Sciences of the United States of America2007139
22Pivotal roles of the parasite PGD2 synthase and of the host D prostanoid receptor 1 in schistosome immune evasionEuropean Journal of Immunology2003137
23Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleepProceedings of the National Academy of Sciences of the United States of America2006137
24Prostaglandin D2 and sleep regulationBiochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids1999134
25Prostaglandin D2-sensitive, sleep-promoting zone defined in the ventral surface of the rostral basal forebrain.Proceedings of the National Academy of Sciences of the United States of America1994131
26Identification of a Fertility-Associated Protein in Bull Seminal Plasma As Lipocalin-Type Prostaglandin D Synthase1Biology of Reproduction1998130
27Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A 1 receptors and promotes non-rapid eye movement sleepProceedings of the National Academy of Sciences of the United States of America2008129
28Cellular localization of lipocalin-type prostaglandin D synthase (?-trace) in the central nervous system of the adult ratJournal of Comparative Neurology2000128
29A Key Role for Old Yellow Enzyme in the Metabolism of Drugs by Trypanosoma cruziJournal of Experimental Medicine2002125
30A metacaspase ofTrypanosoma bruceicauses loss of respiration competence and clonal death in the yeastSaccharomyces cerevisiaeFEBS Letters2002125
31How do the basal ganglia regulate sleep–wake behavior?Trends in Neurosciences2012124
32Minireview: Sleep regulation in adenosine A 2A receptor-deficient miceNeurology2003123
33Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleepProceedings of the National Academy of Sciences of the United States of America2000112
34Region-dependent difference in the sleep-promoting potency of an adenosine A2Areceptor agonistEuropean Journal of Neuroscience1999111
35Identification of a Novel Prostaglandin F2α Synthase in Trypanosoma bruceiJournal of Experimental Medicine2000111
36An Apoptotic Depletion of Oligodendrocytes in the Twitcher, a Murine Model of Globoid Cell LeukodystrophyJournal of Neuropathology and Experimental Neurology1999102
37CSF levels of prostaglandins, especially the level of prostaglandin D2, are correlated with increasing propensity towards sleep in ratsBrain Research1997101
38Prostaglandin D, E, and F synthasesJournal of Lipid Mediators and Cell Signalling199596
39Involvement of adenosine A2A receptor in sleep promotionEuropean Journal of Pharmacology199895
40Lipocalin-Type Prostaglandin D Synthase in Human Male Reproductive Organs and Seminal Plasma1Biology of Reproduction199893
41Structural and Functional Characterization of HQL-79, an Orally Selective Inhibitor of Human Hematopoietic Prostaglandin D SynthaseJournal of Biological Chemistry200691
42Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthaseFEBS Journal200089
43Anti-inflammatory role of PGD 2 in acute lung inflammation and therapeutic application of its signal enhancementProceedings of the National Academy of Sciences of the United States of America201388
44Identification of mu-class glutathione transferases M2-2 and M3-3 as cytosolic prostaglandin E synthases in the human brainNeurochemical Research200087
45Role of prostaglandin D 2 receptor DP as a suppressor of tumor hyperpermeability and angiogenesis in vivoProceedings of the National Academy of Sciences of the United States of America200886
46Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cellsELife201486
47Algorithm for sleep scoring in experimental animals based on fast Fourier transform power spectrum analysis of the electroencephalogramSleep and Biological Rhythms200883
48Prostaglandin F2  Synthase Activities of Aldo-Keto Reductase 1B1, 1B3 and 1B7Journal of Biochemistry200882
49Plasmodium falciparum Produces Prostaglandins that are Pyrogenic, Somnogenic, and Immunosuppressive Substances in HumansJournal of Experimental Medicine199880
50Hematopoietic Prostaglandin D Synthase and DP1 Receptor Are Selectively Upregulated in Microglia and Astrocytes Within Senile Plaques From Human Patients and in a Mouse Model of Alzheimer DiseaseJournal of Neuropathology and Experimental Neurology200778