| # | Title | Journal | Year | Citations |
|---|
| 1 | Cardiac Mitochondria and Reactive Oxygen Species Generation | Circulation Research | 2014 | 449 |
| 2 | Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism | Hepatology | 2018 | 348 |
| 3 | Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7α-hydroxylase gene expression | Hepatology | 2009 | 331 |
| 4 | Bile Acid Metabolism in Liver Pathobiology | Gene Expression | 2018 | 308 |
| 5 | Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases | Biochemical Pharmacology | 2008 | 251 |
| 6 | Bile Acids as Metabolic Regulators and Nutrient Sensors | Annual Review of Nutrition | 2019 | 233 |
| 7 | Bile acids as metabolic regulators | Current Opinion in Gastroenterology | 2015 | 226 |
| 8 | Obstructive Coronary Atherosclerosis and Ischemic Heart Disease: An Elusive Link! | Journal of the American College of Cardiology | 2012 | 216 |
| 9 | A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism | Nature Communications | 2015 | 198 |
| 10 | Bile acid metabolism and signaling in liver disease and therapy | Liver Research | 2017 | 195 |
| 11 | Farnesoid X receptor induces Takeda G-protein receptor 5 cross-talk to regulate bile acid synthesis and hepatic metabolism | Journal of Biological Chemistry | 2017 | 178 |
| 12 | MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47phox–oxidative stress pathway in neutrophils | Gut | 2017 | 173 |
| 13 | Glucose and Insulin Induction of Bile Acid Synthesis | Journal of Biological Chemistry | 2012 | 171 |
| 14 | TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals | Journal of Molecular and Cellular Cardiology | 2013 | 171 |
| 15 | Actomyosin Tension Exerted on the Nucleus through Nesprin-1 Connections Influences Endothelial Cell Adhesion, Migration, and Cyclic Strain-Induced Reorientation | Biophysical Journal | 2010 | 161 |
| 16 | Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 2015 | 152 |
| 17 | The coronary circulation in acute myocardial ischaemia/reperfusion injury: a target for cardioprotection | Cardiovascular Research | 2019 | 151 |
| 18 | Regulation of Bile Acid and Cholesterol Metabolism by PPARs | PPAR Research | 2009 | 150 |
| 19 | Ischemic Heart Disease Pathophysiology Paradigms Overview: From Plaque Activation to Microvascular Dysfunction | International Journal of Molecular Sciences | 2020 | 148 |
| 20 | Nuclear receptors in bile acid metabolism | Drug Metabolism Reviews | 2013 | 140 |
| 21 | Myocardial CXCR4 Expression Is Required for Mesenchymal Stem Cell Mediated Repair Following Acute Myocardial Infarction | Circulation | 2012 | 135 |
| 22 | Recent advances in understanding bile acid homeostasis | F1000Research | 2017 | 135 |
| 23 | AMPK-dependent Repression of Hepatic Gluconeogenesis via Disruption of CREB·CRTC2 Complex by Orphan Nuclear Receptor Small Heterodimer Partner | Journal of Biological Chemistry | 2010 | 130 |
| 24 | Activation of the Farnesoid X Receptor Induces Hepatic Expression and Secretion of Fibroblast Growth Factor 21 | Journal of Biological Chemistry | 2012 | 129 |
| 25 | Regulation of cholesterol and bile acid homeostasis by the cholesterol 7α-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice | Hepatology | 2013 | 129 |
| 26 | Hepatic Hepatocyte Nuclear Factor 4α Is Essential for Maintaining Triglyceride and Cholesterol Homeostasis | Arteriosclerosis, Thrombosis, and Vascular Biology | 2011 | 128 |
| 27 | An Open-Label Dose Escalation Study to Evaluate the Safety of Administration of Nonviral Stromal Cell-Derived Factor-1 Plasmid to Treat Symptomatic Ischemic Heart Failure | Circulation Research | 2013 | 127 |
| 28 | Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy | Oncogene | 2016 | 127 |
| 29 | Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression | Journal of Clinical Investigation | 2017 | 127 |
| 30 | Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice | Hepatology | 2016 | 121 |
| 31 | Bile Acid Signaling in Liver Metabolism and Diseases | Journal of Lipids | 2012 | 112 |
| 32 | Bile acid receptors in non-alcoholic fatty liver disease | Biochemical Pharmacology | 2013 | 111 |
| 33 | Tissue engineering a model for the human ear: Assessment of size, shape, morphology, and gene expression following seeding of different chondrocytes | Wound Repair and Regeneration | 2009 | 109 |
| 34 | Loss of FXR Protects against Diet-Induced Obesity and Accelerates Liver Carcinogenesis in ob/ob Mice | Molecular Endocrinology | 2012 | 108 |
| 35 | Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis | Hepatology | 2014 | 104 |
| 36 | G‐protein‐coupled bile acid receptor plays a key role in bile acid metabolism and fasting‐induced hepatic steatosis in mice | Hepatology | 2017 | 104 |
| 37 | Hepatic lipid homeostasis by peroxisome proliferator-activated receptor gamma 2 | Liver Research | 2018 | 103 |
| 38 | Mineral Deposition in the Extracellular Matrices of Vertebrate Tissues: Identification of Possible Apatite Nucleation Sites on Type I Collagen | Cells Tissues Organs | 2009 | 100 |
| 39 | Up to date on cholesterol 7 alpha-hydroxylase (CYP7A1) in bile acid synthesis | Liver Research | 2020 | 100 |
| 40 | Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice | Hepatology | 2016 | 97 |
| 41 | Identification of Novel Pathways That Control Farnesoid X Receptor-mediated Hypocholesterolemia | Journal of Biological Chemistry | 2010 | 96 |
| 42 | Circadian rhythms in liver metabolism and disease | Acta Pharmaceutica Sinica B | 2015 | 96 |
| 43 | Absence of Type VI Collagen Paradoxically Improves Cardiac Function, Structure, and Remodeling After Myocardial Infarction | Circulation Research | 2012 | 93 |
| 44 | Mechanisms of metabolic coronary flow regulation | Journal of Molecular and Cellular Cardiology | 2012 | 93 |
| 45 | Mechanism of Vitamin D Receptor Inhibition of Cholesterol 7α-Hydroxylase Gene Transcription in Human Hepatocytes | Drug Metabolism and Disposition | 2009 | 90 |
| 46 | Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis | Journal of Lipid Research | 2016 | 89 |
| 47 | PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells | American Journal of Physiology - Heart and Circulatory Physiology | 2011 | 86 |
| 48 | Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR | Molecular Metabolism | 2018 | 85 |
| 49 | Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264.7 cells | Scientific Reports | 2019 | 81 |
| 50 | Impaired function of coronary BKCachannels in metabolic syndrome | American Journal of Physiology - Heart and Circulatory Physiology | 2009 | 77 |
