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Top Articles

#TitleJournalYearCitations
1Protein promiscuity and its implications for biotechnologyNature Biotechnology2009434
2Critical assessment of methods of protein structure prediction (CASP)—Round XIIIProteins: Structure, Function and Bioinformatics2019380
3Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteinsFEMS Microbiology Reviews2011276
4Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closingNature Communications2012255
5Circular dichroism spectroscopy of membrane proteinsChemical Society Reviews2016234
6A comprehensive guide to pilus biogenesis in Gram-negative bacteriaNature Reviews Microbiology2017221
7Thermal Denaturation Studies of Collagen by Microthermal Analysis and Atomic Force MicroscopyBiophysical Journal2011200
8Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystoniaNature Genetics2017186
9Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as the D-box co-receptorNature2011176
10Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizuresNature Communications2015160
11Mycobacterium tuberculosis: Immune evasion, latency and reactivationImmunobiology2012151
12Distinct circular dichroism spectroscopic signatures of polyproline II and unordered secondary structures: Applications in secondary structure analysesProtein Science2014151
13Molecular dynamics of ion transport through the open conformation of a bacterial voltage-gated sodium channelProceedings of the National Academy of Sciences of the United States of America2013149
14Tubulin isoform composition tunes microtubule dynamicsMolecular Biology of the Cell2017146
15Extent of enthalpy–entropy compensation in protein–ligand interactionsProtein Science2011143
16Stability-activity tradeoffs constrain the adaptive evolution of RubisCOProceedings of the National Academy of Sciences of the United States of America2014140
17A reference dataset for the analyses of membrane protein secondary structures and transmembrane residues using circular dichroism spectroscopyBioinformatics2011135
18Cell wall peptidoglycan inMycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogenFEMS Microbiology Reviews2019131
19The Microbiome and AgingAnnual Review of Genetics2019127
20Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonismProceedings of the National Academy of Sciences of the United States of America2014120
21Structure of an Apoptosome-Procaspase-9 CARD ComplexStructure2010118
22The complete structure of an activated open sodium channelNature Communications2017118
23Inferential Optimization for Simultaneous Fitting of Multiple Components into a CryoEM Map of Their AssemblyJournal of Molecular Biology2009117
24Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregaseScience Advances2017112
25The role of tubulin–tubulin lattice contacts in the mechanism of microtubule dynamic instabilityNature Structural and Molecular Biology2018112
26Structure and Dynamics of Single-isoform Recombinant Neuronal Human TubulinJournal of Biological Chemistry2016111
27Mechanism of eIF6-mediated Inhibition of Ribosomal Subunit JoiningJournal of Biological Chemistry2010107
28Refinement of atomic models in high resolution EM reconstructions using Flex-EM and local assessmentMethods2016101
29Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesinsELife2014100
30Protein characterisation by synchrotron radiation circular dichroism spectroscopyQuarterly Reviews of Biophysics200999
31Molecular basis of ion permeability in a voltage‐gated sodium channelEMBO Journal201695
32Two distinct trimeric conformations of natively membrane-anchored full-length herpes simplex virus 1 glycoprotein BProceedings of the National Academy of Sciences of the United States of America201693
33Spontaneous transmembrane helix insertion thermodynamically mimics translocon-guided insertionNature Communications201491
34Structure of the dynein-2 complex and its assembly with intraflagellar transport trainsNature Structural and Molecular Biology201991
35Structure of a Pentavalent G-Actin•MRTF-A Complex Reveals How G-Actin Controls Nucleocytoplasmic Shuttling of a Transcriptional CoactivatorScience Signaling201190
36CDtoolX, a downloadable software package for processing and analyses of circular dichroism spectroscopic dataProtein Science201889
37A structural model for microtubule minus-end recognition and protection by CAMSAP proteinsNature Structural and Molecular Biology201786
38Immunological features of α‐synuclein in Parkinson's diseaseJournal of Cellular and Molecular Medicine200884
39CryoEM reveals how the complement membrane attack complex ruptures lipid bilayersNature Communications201883
40PCDDB: the protein circular dichroism data bank, a repository for circular dichroism spectral and metadataNucleic Acids Research201179
41The Importance of Non-accessible Crosslinks and Solvent Accessible Surface Distance in Modeling Proteins with Restraints From Crosslinking Mass SpectrometryMolecular and Cellular Proteomics201679
42Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosisJournal of Antimicrobial Chemotherapy201077
43ATP‐driven molecular chaperone machinesBiopolymers201376
44TEMPy: a Python library for assessment of three-dimensional electron microscopy density fitsJournal of Applied Crystallography201575
45Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assayBMJ Open201374
46Structure of the Drosophila Apoptosome at 6.9 Å ResolutionStructure201173
47Role of the C-terminal domain in the structure and function of tetrameric sodium channelsNature Communications201371
48Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosisPLoS ONE201371
49An integrated surrogate model for screening of drugs against Mycobacterium tuberculosisJournal of Antimicrobial Chemotherapy201268
50Surface architecture of endospores of the Bacillus cereus/anthracis/thuringiensis family at the subnanometer scaleProceedings of the National Academy of Sciences of the United States of America201167