| # | Title | Journal | Year | Citations |
|---|
| 1 | Antimicrobial wound dressing and anti-inflammatory efficacy of silver nanoparticles | International Journal of Biological Macromolecules | 2014 | 222 |
| 2 | Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells | Toxicology Letters | 2018 | 127 |
| 3 | Citric Acid Effects on Brain and Liver Oxidative Stress in Lipopolysaccharide-Treated Mice | Journal of Medicinal Food | 2014 | 106 |
| 4 | Thymoquinone synergizes gemcitabine anti-breast cancer activity via modulating its apoptotic and autophagic activities | Scientific Reports | 2018 | 97 |
| 5 | Immunological studies on Amaranth, Sunset Yellow and Curcumin as food colouring agents in albino rats | Food and Chemical Toxicology | 2010 | 86 |
| 6 | Evaluation of the safety and antioxidant activities of Crocus sativus and Propolis ethanolic extracts | Journal of Saudi Chemical Society | 2012 | 72 |
| 7 | Ochratoxicosis: prevention of developmental toxicity by L-methionine in rats | Journal of Applied Toxicology | 1999 | 67 |
| 8 | Anti-inflammatory and antioxidant activities of naringin isolated from Carissa carandas L.: In vitro and in vivo evidence | Phytomedicine | 2018 | 61 |
| 9 | Potential protective effect of HSCAS and bentonite against dietary aflatoxicosis in rat: with special reference to chromosomal aberrations | Natural Toxins | 1998 | 60 |
| 10 | Novel CoQ10 Antidiabetic Mechanisms Underlie Its Positive Effect: Modulation of Insulin and Adiponectine Receptors, Tyrosine Kinase, PI3K, Glucose Transporters, sRAGE and Visfatin in Insulin Resistant/Diabetic Rats | PLoS ONE | 2014 | 60 |
| 11 | Antihypercholesterolaemic effect of ginger rhizome (Zingiber officinale) in rats | Inflammopharmacology | 2010 | 58 |
| 12 | Antineoplastic Activity and Curative Role of Avenanthramides against the Growth of Ehrlich Solid Tumors in Mice | Oxidative Medicine and Cellular Longevity | 2019 | 58 |
| 13 | Protective role of chrysin on thioacetamide-induced hepatic encephalopathy in rats | Chemico-Biological Interactions | 2019 | 55 |
| 14 | Anti-Alzheimer potential, metabolomic profiling and molecular docking of green synthesized silver nanoparticles of Lampranthus coccineus and Malephora lutea aqueous extracts | PLoS ONE | 2019 | 51 |
| 15 | Prophylactic role of coenzyme Q10 and Cynara scolymus L on doxorubicin-induced toxicity in rats: Biochemical and immunohistochemical study | Indian Journal of Pharmacology | 2015 | 51 |
| 16 | Role of zinc oxide nanoparticles in alleviating hepatic fibrosis and nephrotoxicity induced by thioacetamide in rats | Canadian Journal of Physiology and Pharmacology | 2018 | 48 |
| 17 | Phytochemical constituents and hepatoprotective activity of Viburnum tinus | Phytochemistry | 2005 | 47 |
| 18 | Antihypertensive and Cardioprotective Effects of Pumpkin Seed Oil | Journal of Medicinal Food | 2012 | 47 |
| 19 | Anti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent | Journal of Enzyme Inhibition and Medicinal Chemistry | 2012 | 46 |
| 20 | Stem Cell Therapy for Alzheimers Disease | CNS and Neurological Disorders - Drug Targets | 2011 | 43 |
| 21 | Tissue Distribution and Efficacy of Gold Nanorods Coupled with Laser Induced Photoplasmonic Therapy in Ehrlich Carcinoma Solid Tumor Model | PLoS ONE | 2013 | 43 |
| 22 | Folic acid and melatonin mitigate diabetic nephropathy in rats via inhibition of oxidative stress | Nutrition and Metabolism | 2020 | 42 |
| 23 | Bioactive constituents from Harpephyllum caffrum Bernh. and Rhus coriaria L | Pharmacognosy Magazine | 2011 | 41 |
| 24 | Neuroprotective effect of vildagliptin against cerebral ischemia in rats | Naunyn-Schmiedeberg's Archives of Pharmacology | 2018 | 41 |
| 25 | Liraglutide ameliorated peripheral neuropathy in diabetic rats: Involvement of oxidative stress, inflammation and extracellular matrix remodeling | Journal of Neurochemistry | 2018 | 40 |
| 26 | Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases | European Journal of Medicinal Chemistry | 2020 | 40 |
| 27 | Anti-Inflammatory, Antinociceptive, and Gastric Effects ofHypericum perforatumin Rats | Scientific World Journal, The | 2005 | 39 |
| 28 | Promising targets of chrysin and daidzein in colorectal cancer: Amphiregulin, CXCL1, and MMP-9 | European Journal of Pharmacology | 2021 | 39 |
| 29 | Drugs Used to Treat Parkinsons Disease, Present Status and Future Directions | CNS and Neurological Disorders - Drug Targets | 2008 | 39 |
| 30 | Hepatoprotective effects of misoprostol and silymarin on carbon tetrachloride‐induced hepatic damage in rats | Fundamental and Clinical Pharmacology | 2009 | 38 |
| 31 | Protective effect of royal jelly against diclofenac-induced hepato-renal damage and gastrointestinal ulcerations in rats | Heliyon | 2020 | 37 |
| 32 | Extracellular Matrix Remodeling and Modulation of Inflammation and Oxidative Stress by Sulforaphane in Experimental Diabetic Peripheral Neuropathy | Inflammation | 2018 | 36 |
| 33 | Olive leaves extract attenuates type II diabetes mellitus-induced testicular damage in rats: Molecular and biochemical study | Saudi Pharmaceutical Journal | 2019 | 36 |
| 34 | Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile | Bioorganic Chemistry | 2021 | 36 |
| 35 | The Anti-fibrotic and Anti-inflammatory Potential of Bone Marrow–Derived Mesenchymal Stem Cells and Nintedanib in Bleomycin-Induced Lung Fibrosis in Rats | Inflammation | 2020 | 35 |
| 36 | Protective effect ofCalligonum comosumon haloperidol-induced oxidative stress in rat | Toxicology and Industrial Health | 2014 | 34 |
| 37 | Therapeutic effect of pectin on octylphenol induced kidney dysfunction, oxidative stress and apoptosis in rats | Environmental Toxicology and Pharmacology | 2014 | 34 |
| 38 | Estimation of ellagic acid and/or repaglinide effects on insulin signaling, oxidative stress, and inflammatory mediators of liver, pancreas, adipose tissue, and brain in insulin resistant/type 2 diabetic rats | Applied Physiology, Nutrition and Metabolism | 2017 | 34 |
| 39 | Efficient wound healing composite hydrogel using Egyptian Avena sativa L. polysaccharide containing β-glucan | International Journal of Biological Macromolecules | 2020 | 34 |
| 40 | Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening | RSC Advances | 2020 | 34 |
| 41 | Anti-inflammatory, Analgesic and Anti-ulcerogenic Activities of Novel bis-thiadiazoles, bis-thiazoles and bis-formazanes | Medicinal Chemistry | 2017 | 34 |
| 42 | Immunogenicity and Safety of an Inactivated SARS-CoV-2 Vaccine: Preclinical Studies | Vaccines | 2021 | 33 |
| 43 | Metformin and trimetazidine ameliorate diabetes-induced cognitive impediment in status epileptic rats | Epilepsy and Behavior | 2020 | 32 |
| 44 | Oxidative Stress in a Model of Toxic Demyelination in Rat Brain: The Effect of Piracetam and Vinpocetine | Neurochemical Research | 2011 | 31 |
| 45 | Extracellular myco-synthesis of nano-silver using the fermentable yeasts Pichia kudriavzeviiHA-NY2 and Saccharomyces uvarumHA-NY3, and their effective biomedical applications | Bioprocess and Biosystems Engineering | 2021 | 31 |
| 46 | Safety Evaluation of a Bioglass–Polylactic Acid Composite Scaffold Seeded with Progenitor Cells in a Rat Skull Critical-Size Bone Defect | PLoS ONE | 2014 | 31 |
| 47 | <p>Synthesis, comparative docking, and pharmacological activity of naproxen amino acid derivatives as possible anti-inflammatory and analgesic agents</p> | Drug Design, Development and Therapy | 2019 | 30 |
| 48 | Propolis ameliorates cerebral injury in focal cerebral ischemia/reperfusion (I/R) rat model via upregulation of TGF-β1 | Saudi Pharmaceutical Journal | 2020 | 30 |
| 49 | Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence | Chemico-Biological Interactions | 2021 | 30 |
| 50 | Design, characterization and in vivo performance of solid lipid nanoparticles (SLNs)-loaded mucoadhesive buccal tablets for efficient delivery of Lornoxicam in experimental inflammation | International Journal of Pharmaceutics | 2022 | 30 |
