| # | Title | Journal | Year | Citations |
|---|
| 1 | Topographical and Temporal Diversity of the Human Skin Microbiome | Science | 2009 | 2,280 |
| 2 | An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome | Nature Genetics | 2014 | 585 |
| 3 | Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources | Nucleic Acids Research | 2019 | 539 |
| 4 | Common Severe Infections in Chronic Granulomatous Disease | Clinical Infectious Diseases | 2015 | 323 |
| 5 | An immune-based biomarker signature is associated with mortality in COVID-19 patients | JCI Insight | 2021 | 269 |
| 6 | Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents | Clinical Infectious Diseases | 2018 | 234 |
| 7 | The distribution of T‐cell subsets and the expression of immune checkpoint receptors and ligands in patients with newly diagnosed and relapsed acute myeloid leukemia | Cancer | 2019 | 229 |
| 8 | Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy | JCI Insight | 2016 | 219 |
| 9 | Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates | Genome Biology | 2012 | 206 |
| 10 | Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 206 |
| 11 | Acute GVHD in patients receiving IL-15/4-1BBL activated NK cells following T-cell–depleted stem cell transplantation | Blood | 2015 | 200 |
| 12 | CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System | PLoS Pathogens | 2015 | 184 |
| 13 | Germline hypomorphic CARD11 mutations in severe atopic disease | Nature Genetics | 2017 | 174 |
| 14 | Genome-wide recombination drives diversification of epidemic strains of Acinetobacter baumannii | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 169 |
| 15 | Congenital B cell lymphocytosis explained by novel germline CARD11 mutations | Journal of Experimental Medicine | 2012 | 167 |
| 16 | Neutralizing antibodies to therapeutic enzymes: considerations for testing, prevention and treatment | Nature Biotechnology | 2008 | 148 |
| 17 | Conversion of Urine Protein–Creatinine Ratio or Urine Dipstick Protein to Urine Albumin–Creatinine Ratio for Use in Chronic Kidney Disease Screening and Prognosis | Annals of Internal Medicine | 2020 | 144 |
| 18 | Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation | Journal of Translational Medicine | 2010 | 141 |
| 19 | Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis | Blood | 2011 | 139 |
| 20 | Host-Dependent Patterns of Tissue Injury in Invasive Pulmonary Aspergillosis | American Journal of Clinical Pathology | 2007 | 137 |
| 21 | Gray platelet syndrome: natural history of a large patient cohort and locus assignment to chromosome 3p | Blood | 2010 | 137 |
| 22 | Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib | Haematologica | 2015 | 137 |
| 23 | Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia | Blood | 2010 | 134 |
| 24 | Association of Sickle Cell Trait With Hemoglobin A1c in African Americans | JAMA - Journal of the American Medical Association | 2017 | 122 |
| 25 | Detection of a Molecular Biomarker for Zygomycetes by Quantitative PCR Assays of Plasma, Bronchoalveolar Lavage, and Lung Tissue in a Rabbit Model of Experimental Pulmonary Zygomycosis | Journal of Clinical Microbiology | 2008 | 112 |
| 26 | Adjuvant Immunotherapy to Improve Outcome in High-Risk Pediatric Sarcomas | Clinical Cancer Research | 2016 | 109 |
| 27 | Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications | Haematologica | 2011 | 97 |
| 28 | Detection of Intracellular Phosphorylated STAT-4 by Flow Cytometry | Clinical Immunology | 2001 | 95 |
| 29 | Can Mass Spectrometric Protein Profiling Meet Desired Standards of Clinical Laboratory Practice? | Clinical Chemistry | 2005 | 90 |
| 30 | Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells | Blood | 2017 | 89 |
| 31 | Scavenger receptor-BI is a receptor for lipoprotein(a) | Journal of Lipid Research | 2013 | 87 |
| 32 | Outbreak of Human Parainfluenza Virus 3 Infections in a Hematopoietic Stem Cell Transplant Population | Journal of Infectious Diseases | 2001 | 86 |
| 33 | Effect of Blood Collection Tubes on Total Triiodothyronine and Other Laboratory Assays | Clinical Chemistry | 2005 | 86 |
| 34 | Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation for GATA2 Deficiency | Biology of Blood and Marrow Transplantation | 2014 | 84 |
| 35 | Selective serotonin reuptake inhibitors: measurement of effect on platelet function | Translational Research | 2008 | 82 |
| 36 | IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion | Clinical Cancer Research | 2019 | 82 |
| 37 | EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay | Journal of Experimental Medicine | 2017 | 76 |
| 38 | Allogeneic Hematopoietic Stem Cell Transplantation for GATA2 Deficiency Using a Busulfan-Based Regimen | Biology of Blood and Marrow Transplantation | 2018 | 71 |
| 39 | MicroRNA-27b up-regulated by human papillomavirus 16 E7 promotes proliferation and suppresses apoptosis by targeting polo-like kinase2 in cervical cancer | Oncotarget | 2016 | 65 |
| 40 | Diagnostic potential for urinary proteomics | Pharmacogenomics | 2007 | 61 |
| 41 | Clinical and molecular characterization of a re‐established line of sheep exhibiting hemophilia A | Journal of Thrombosis and Haemostasis | 2010 | 60 |
| 42 | Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria | Emerging Microbes and Infections | 2016 | 59 |
| 43 | A seven-day study of the pharmacokinetics of intravenous levetiracetam in neonates: marked changes in pharmacokinetics occur during the first week of life | Pediatric Research | 2012 | 58 |
| 44 | Treatment of anti-MDA5 autoantibody-positive juvenile dermatomyositis using tofacitinib | Brain | 2019 | 58 |
| 45 | Immunoassay Interference by a Commonly Used Blood Collection Tube Additive, the Organosilicone Surfactant Silwet L-720 | Clinical Chemistry | 2005 | 57 |
| 46 | Low- versus High-Baseline Epinephrine Output Shapes Opposite Innate Cytokine Profiles: Presence of Lewis- and Fischer-Like Neurohormonal Immune Phenotypes in Humans? | Journal of Immunology | 2008 | 57 |
| 47 | Outbreak of Pneumocystis Pneumonia in Renal and Liver Transplant Patients Caused by Genotypically Distinct Strains of Pneumocystis jirovecii | Transplantation | 2013 | 57 |
| 48 | Clinical Trial of Quantitative Real‐Time Polymerase Chain Reaction for Detection of Cytomegalovirus in Peripheral Blood of Allogeneic Hematopoietic Stem‐Cell Transplant Recipients | Journal of Infectious Diseases | 2003 | 54 |
| 49 | Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance | Immunity | 2016 | 54 |
| 50 | Sepsis caused by Elizabethkingia miricola successfully treated with tigecycline and levofloxacin | Diagnostic Microbiology and Infectious Disease | 2008 | 53 |
