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| Pulmonary rehabilitation for chronic obstructive pulmonary disease | Cochrane Database of Systematic Reviews | 2006 | 428 |
| Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo | Journal of Clinical Investigation | 2006 | 386 |
| Adiponectin and coronary heart disease: a prospective study and meta-analysis | Circulation | 2006 | 356 |
| Sample size for cluster randomized trials: effect of coefficient of variation of cluster size and analysis method | International Journal of Epidemiology | 2006 | 329 |
| Cellular senescence in naevi and immortalisation in melanoma: a role for p16? | British Journal of Cancer | 2006 | 322 |
| Does breastfeeding influence risk of type 2 diabetes in later life? A quantitative analysis of published evidence | American Journal of Clinical Nutrition | 2006 | 320 |
| Variations in primary open-angle glaucoma prevalence by age, gender, and race: a Bayesian meta-analysis | Investigative Ophthalmology and Visual Science | 2006 | 309 |
| Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin | Journal of Infectious Diseases | 2006 | 285 |
| Microarrays reveal that each of the ten dominant lineages of Staphylococcus aureus has a unique combination of surface-associated and regulatory genes | Journal of Bacteriology | 2006 | 271 |
| Efficacy of cognitive-behavioral interventions targeting personality risk factors for youth alcohol misuse | Journal of Clinical Child and Adolescent Psychology | 2006 | 268 |
| Measuring intra-operative interference from distraction and interruption observed in the operating theatre | Ergonomics | 2006 | 237 |
| Sau1: a novel lineage-specific type I restriction-modification system that blocks horizontal gene transfer into Staphylococcus aureus and between S. aureus isolates of different lineages | Journal of Bacteriology | 2006 | 234 |
| Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria | Clinical Infectious Diseases | 2006 | 228 |
| Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk | Diabetes | 2006 | 222 |
| Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis | American Journal of Clinical Nutrition | 2006 | 217 |
| Combining information from common type 2 diabetes risk polymorphisms improves disease prediction | PLoS Medicine | 2006 | 214 |
| Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum | Lancet, The | 2006 | 208 |
| The impact of CT image integration into an electroanatomic mapping system on clinical outcomes of catheter ablation of atrial fibrillation | Journal of Cardiovascular Electrophysiology | 2006 | 200 |
| The NPro product of bovine viral diarrhea virus inhibits DNA binding by interferon regulatory factor 3 and targets it for proteasomal degradation | Journal of Virology | 2006 | 197 |
| Selective transmission of CCR5-utilizing HIV-1: the 'gatekeeper' problem resolved? | Nature Reviews Microbiology | 2006 | 191 |
| Differential subcellular distribution of glucose transporters GLUT1-6 and GLUT9 in human cancer: ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues | Journal of Cellular Physiology | 2006 | 189 |
| Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes | Molecular and Cellular Biology | 2006 | 187 |
| Internet information-seeking in mental health: population survey | British Journal of Psychiatry | 2006 | 185 |
| Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains | Journal of Bacteriology | 2006 | 178 |
