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Molecular Immunology and Inflammation Branch
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top-articles
Molecular Immunology and Inflammation Branch
158
(top 1%)
papers
25.1K
(top 1%)
citations
75
(top 1%)
h
-index
156
(top 0.1%)
g
-index
164
all documents
26.8K
doc citations
2.6K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Mechanisms Underlying Lineage Commitment and Plasticity of Helper CD4
+
T Cells
Science
2010
1,151
2
Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Nature
2008
1,046
3
Janus kinases in immune cell signaling
Immunological Reviews
2009
982
4
JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease
Immunity
2012
933
5
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo
Nature Immunology
2009
921
6
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
Nature Reviews Drug Discovery
2017
759
7
JAKs and STATs in Immunity, Immunodeficiency, and Cancer
New England Journal of Medicine
2013
738
8
Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22
Journal of Experimental Medicine
2009
653
9
Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis
Immunity
2010
605
10
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease
Nature Genetics
2010
595
11
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
Proceedings of the National Academy of Sciences of the United States of America
2006
580
12
Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)
Journal of Immunology
2011
569
13
IL-21 Is Produced by Th17 Cells and Drives IL-17 Production in a STAT3-dependent Manner
Journal of Biological Chemistry
2007
549
14
Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease
Nature Genetics
2016
513
15
The Janus kinases (Jaks)
Genome Biology
2004
508
16
Nonredundant roles for Stat5a/b in directly regulating Foxp3
Blood
2007
488
17
The biology of IL-12: coordinating innate and adaptive immune responses
Cytokine and Growth Factor Reviews
2003
476
18
Critical Role for STAT4 Activation by Type 1 Interferons in the Interferon-gamma Response to Viral Infection
Science
2002
443
19
Molecular regulation of mast cell activation
Journal of Allergy and Clinical Immunology
2006
427
20
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4
+
T cells
Science
2016
395
21
Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
Blood
2008
392
22
Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature
Immunity
2011
392
23
IFN Regulatory Factor-4 and -8 Govern Dendritic Cell Subset Development and Their Functional Diversity
Journal of Immunology
2005
390
24
Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition
Immunity
2011
364
25
Janus kinase inhibitors in autoimmune diseases
Annals of the Rheumatic Diseases
2013
350
26
Stat5a/b are essential for normal lymphoid development and differentiation
Proceedings of the National Academy of Sciences of the United States of America
2006
331
27
STATs Shape the Active Enhancer Landscape of T Cell Populations
Cell
2012
325
28
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair
Cell
2018
323
29
The ins and outs of IgE-dependent mast-cell exocytosis
Trends in Immunology
2004
295
30
Discrete Roles of STAT4 and STAT6 Transcription Factors in Tuning Epigenetic Modifications and Transcription during T Helper Cell Differentiation
Immunity
2010
290
31
Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome
Blood
2018
288
32
A new modality for immunosuppression: targeting the JAK/STAT pathway
Nature Reviews Drug Discovery
2004
275
33
Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality
Cell
2016
273
34
Helper T cell diversity and plasticity
Current Opinion in Immunology
2012
267
35
Genomic views of STAT function in CD4+ T helper cell differentiation
Nature Reviews Immunology
2011
251
36
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones
Nature Structural and Molecular Biology
2014
247
37
BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers
Nature Immunology
2016
221
38
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury
Science
2019
219
39
Therapeutic targeting of Janus kinases
Immunological Reviews
2008
212
40
The Sphingosine Kinase-Sphingosine-1-Phosphate Axis Is a Determinant of Mast Cell Function and Anaphylaxis
Immunity
2007
200
41
Negative Regulation of Immunoglobulin E–dependent Allergic Responses by Lyn Kinase
Journal of Experimental Medicine
2004
193
42
Jakinibs: a new class of kinase inhibitors in cancer and autoimmune disease
Current Opinion in Pharmacology
2012
193
43
T helper 17 cell heterogeneity and pathogenicity in autoimmune disease
Trends in Immunology
2011
187
44
Tofacitinib Ameliorates Murine Lupus and Its Associated Vascular Dysfunction
Arthritis and Rheumatology
2017
183
45
A20 haploinsufficiency (HA20): clinical phenotypes and disease course of patients with a newly recognised NF-kB-mediated autoinflammatory disease
Annals of the Rheumatic Diseases
2018
176
46
STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells during Acute Murine Graft-versus-Host Disease
Immunity
2012
164
47
Molecular adapters in FcεRI signaling and the allergic response
Current Opinion in Immunology
2002
162
48
Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium
Cell
2019
159
49
Sphingosine Kinase Type 1 Induces G12/13-mediated Stress Fiber Formation, yet Promotes Growth and Survival Independent of G Protein-coupled Receptors
Journal of Biological Chemistry
2003
142
50
Preferential Signaling and Induction of Allergy-promoting Lymphokines Upon Weak Stimulation of the High Affinity IgE Receptor on Mast Cells
Journal of Experimental Medicine
2003
137
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