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Top Articles

#TitleJournalYearCitations
1Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancerCancer Research1999291
2Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patientsBreast Cancer Research and Treatment2005277
3Manganese Superoxide Dismutase-Mediated Gene Expression in Radiation-Induced Adaptive ResponsesMolecular and Cellular Biology2003263
4Cigarette Smoking, N-Acetyltransferase 2 Genetic Polymorphisms, and Breast Cancer RiskJAMA - Journal of the American Medical Association1996230
5Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expressionPharmacogenetics and Genomics2001203
6Characterization of a common deletion polymorphism of the UGT2B17 gene linked to UGT2B15Genomics2004144
7Genetic polymorphisms in catechol-O-methyltransferase, menopausal status, and breast cancer riskCancer Research1998135
8Carcinogen substrate specificity of human COX-1 and COX-2Carcinogenesis2001133
9Gene and Protein Characterization of the Human Glutathione S-Transferase Kappa and Evidence for a Peroxisomal LocalizationJournal of Biological Chemistry2004120
10Frequency ofCYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese populationInternational Journal of Cancer2001115
11Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomasPharmacogenetics and Genomics2002111
12Chemopreventive Effects of Tea Extracts and Various Components on Human Pancreatic and Prostate Tumor Cells In VitroNutrition and Cancer1999101
13Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controlsPharmacogenetics and Genomics200097
14Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissectionCancer Research200295
15Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic aminesChemico-Biological Interactions199893
16Breast cancer risk, meat consumption and N-acetyltransferase (NAT2) genetic polymorphisms199892
17Interindividual variation and organ-specific patterns of glutathione S-transferase alpha, mu, and pi expression in gastrointestinal tract mucosa of normal individualsArchives of Biochemistry and Biophysics200283
18Relationship of phenol sulfotransferase activity (SULT1A1) genotype to sulfotransferase phenotype in platelet cytosolPharmacogenetics and Genomics200082
19Association between a glutathioneS-transferase A1 promoter polymorphism and survival after breast cancer treatmentInternational Journal of Cancer200382
20Genetic variants in SOD2, MPO, and NQO1, and risk of ovarian cancerGynecologic Oncology200480
21Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathyMetabolism: Clinical and Experimental200179
22Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer riskCancer Causes and Control199975
23Increased expression of heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP) in pancreatic tissue from smokers and pancreatic tumor cellsCancer Letters200273
24Impact of metabolic genotypes on levels of biomarkers of genotoxic exposureMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis200165
25Detoxification of carcinogenic aromatic and heterocyclic amines by enzymatic reduction of the N-hydroxy derivativeCancer Letters199960
26Measuring S-adenosylmethionine in whole blood, red blood cells and cultured cells using a fast preparation method and high-performance liquid chromatographyBiomedical Applications199756
27Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepaticN-acetyltransferase and glutathioneS-transferase activitiesEnvironmental and Molecular Mutagenesis200451
28Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cellsEnvironmental and Molecular Mutagenesis200249
29Cigarette smoking, N-acetyltransferase 2 genetic polymorphisms, and breast cancer riskJAMA - Journal of the American Medical Association199649
30Metabolism of 2-amino-alpha-carboline. A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2Drug Metabolism and Disposition199647
31Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction methodPharmacogenetics and Genomics199946
32Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesisCarcinogenesis200344
33Increased levels of NAD(P)H: quinone oxidoreductase 1 (NQO1) in pancreatic tissues from smokers and pancreatic adenocarcinomas: A potential biomarker of early damage in the pancreasCell Biology and Toxicology200642
34An evaluation of proposed frameworks for grouping polychlorinated biphenyl (PCB) congener data into meaningful analytic units199940
35Expression of hGSTP1 alleles in human lung and catalytic activity of the native protein variants towards 1-chloro-2,4-dinitrobenzene, 4-vinylpyridine and (+)-anti benzo[a]pyrene-7,8-diol-9,10-oxideCancer Letters200038
36In vitro bioactivation of N-hydroxy-2-amino-alpha-carbolineCarcinogenesis200038
37Toward an Integrated Approach to Molecular EpidemiologyAmerican Journal of Epidemiology199737
38Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with dietCancer Epidemiology Biomarkers and Prevention200137
39Comparison of DNA adduct levels associated with exogenous and endogenous exposures in human pancreas in relation to metabolic genotypeMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis199936
40CYP3A43 Pro340Ala Polymorphism and Prostate Cancer Risk in African Americans and CaucasiansCancer Epidemiology Biomarkers and Prevention200536
41Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancerToxicology200235
42Plasma Carotenoids and Prostate Cancer: A Population-Based Case-Control Study in ArkansasNutrition and Cancer200735
43Quantitative analysis of interindividual variation of glutathione S-transferase expression in human pancreas and the ambiguity of correlating genotype with phenotypeCancer Research200035
44Lack of association between Caucasian lung cancer risk and O6-methylguanine-DNA methyltransferase-codon 178 genetic polymorphismLung Cancer200434
45Glutathione-S-transferase (GSTM1) Genetic Polymorphisms Do Not Affect Human Breast Cancer Risk, Regardless of Dietary AntioxidantsJournal of Nutrition199933
46Increased expression of hepatic DNA methyltransferase in smokersCell Biology and Toxicology199930
47The CYP3A4*1B variant is related to the onset of puberty, a known risk factor for the development of breast cancerCancer Epidemiology Biomarkers and Prevention200330
48Mitochondrial Mutagenesis and Oxidative Stress in Human Prostate CancerJournal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews200429
49Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissueLung Cancer200225
50The effects of phytoestrogens on human pancreatic tumor cells in vitroCancer Letters199924