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Top Articles

#TitleJournalYearCitations
1Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell ResponsesCell20151,044
2GhrelinMolecular Metabolism2015810
3Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiomeAlzheimer's and Dementia2019396
4N6 -Methyladenosine in Flaviviridae Viral RNA Genomes Regulates InfectionCell Host and Microbe2016370
5International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk lociNature Communications2019363
6ANGPTL3 Deficiency and Protection Against Coronary Artery DiseaseJournal of the American College of Cardiology2017348
7BCAA catabolism in brown fat controls energy homeostasis through SLC25A44Nature2019332
8Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesityNature Genetics2018286
9Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithmELife2020268
10T cell metabolic fitness in antitumor immunityTrends in Immunology2015237
11Energy Metabolic Reprogramming in the Hypertrophied and Early Stage Failing HeartCirculation: Heart Failure2014233
12Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkersAlzheimer's and Dementia2019198
13AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and SurvivalCell Metabolism2016195
14Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonistJCI Insight2020177
15SIRT3 regulates progression and development of diseases of agingTrends in Endocrinology and Metabolism2015167
16β Cell tone is defined by proglucagon peptides through cAMP signalingJCI Insight2019167
17The Role of the Immune Cells in Fracture HealingCurrent Osteoporosis Reports2018152
18Novel loci and pathways significantly associated with longevityScientific Reports2016145
19Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory SupportJournal of the American College of Cardiology2016143
20Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid BiomarkersJAMA Network Open2019142
21Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophreniaNature Communications2018141
22Modification of messenger RNA by 2′-O-methylation regulates gene expression in vivoNature Communications2019134
23Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscleBiomaterials2019121
24Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolomeNature Communications2020115
25Revisiting the Complexity of GLP-1 Action from Sites of Synthesis to Receptor ActivationEndocrine Reviews2021115
26Erythromyeloid progenitors give rise to a population of osteoclasts that contribute to bone homeostasis and repairNature Cell Biology2020114
27Targeting the Incretin/Glucagon System With Triagonists to Treat DiabetesEndocrine Reviews2018113
28Pyruvate dehydrogenase complex and nicotinamide nucleotide transhydrogenase constitute an energy-consuming redox circuitBiochemical Journal2015103
29The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysisArthritis Research and Therapy201598
30A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver InjuryGastroenterology201997
31N6-methyladenosine is required for the hypoxic stabilization of specific mRNAsRna201792
32Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysisOsteoarthritis and Cartilage201590
33Pyruvate Kinase Controls Signal Strength in the Insulin Secretory PathwayCell Metabolism202088
34A stepwise reduction in plasma and salivary nitrite with increasing strengths of mouthwash following a dietary nitrate loadNitric Oxide - Biology and Chemistry201687
35Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in miceNature Communications201887
36Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis RiskCell201783
37Early nurture epigenetically tunes the oxytocin receptorPsychoneuroendocrinology201983
38Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease PathogenesisPLoS Genetics201581
39The Acetyl Group Buffering Action of Carnitine Acetyltransferase Offsets Macronutrient-Induced Lysine Acetylation of Mitochondrial ProteinsCell Reports201677
40Repositioning Glucagon Action in the Physiology and Pharmacology of DiabetesDiabetes202077
41Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunctionEuropean Heart Journal201674
42Glutamine Metabolism Regulates the Pluripotency Transcription Factor OCT4Cell Reports201670
43Biomarkers and proteomic analysis of osteoarthritisMatrix Biology201468
44daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survivalELife201768
45GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cellsScience Advances202166
46A Guide for a Cardiovascular Genomics Biorepository: the CATHGEN ExperienceJournal of Cardiovascular Translational Research201564
47Synovial Fluid Profile at the Time of Anterior Cruciate Ligament Reconstruction and Its Association With Cartilage Matrix Composition 3 Years After SurgeryAmerican Journal of Sports Medicine201864
48Immune cell extracellular vesicles and their mitochondrial content decline with ageingImmunity and Ageing202064
49A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelializationCell202163
50Thermogenesis in Adipose Tissue Activated by Thyroid HormoneInternational Journal of Molecular Sciences202062