| # | Title | Journal | Year | Citations |
|---|
| 1 | The human microbiome: at the interface of health and disease | Nature Reviews Genetics | 2012 | 2,798 |
| 2 | Macrophages in the Pathogenesis of Atherosclerosis | Cell | 2011 | 2,122 |
| 3 | Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences | Cell | 2014 | 1,493 |
| 4 | Stereospecific Binding of the Potent Narcotic Analgesic [3H]Etorphine to Rat-Brain Homogenate | Proceedings of the National Academy of Sciences of the United States of America | 1973 | 931 |
| 5 | Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma | Nature | 1993 | 859 |
| 6 | Stress-Induced Phosphorylation and Activation of the Transcription Factor CHOP (GADD153) by p38 MAP Kinase | Science | 1996 | 819 |
| 7 | A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. | Proceedings of the National Academy of Sciences of the United States of America | 1992 | 702 |
| 8 | Depletion of L-3,5,3'-Triiodothyronine and L-Thyroxine in Euthyroid Calf Serum for Use in Cell Culture Studies of the Action of Thyroid Hormone* | Endocrinology | 1979 | 662 |
| 9 | Signals from the Stressed Endoplasmic Reticulum Induce C/EBP-Homologous Protein (CHOP/GADD153) | Molecular and Cellular Biology | 1996 | 635 |
| 10 | Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. | Journal of Clinical Investigation | 1992 | 631 |
| 11 | The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. | Journal of Clinical Investigation | 1993 | 594 |
| 12 | Ataxia with isolated vitamin E deficiency is caused by mutations in the α–tocopherol transfer protein | Nature Genetics | 1995 | 590 |
| 13 | Variation in COVID-19 Hospitalizations and Deaths Across New York City Boroughs | JAMA - Journal of the American Medical Association | 2020 | 577 |
| 14 | Adenosine, an endogenous anti-inflammatory agent | Journal of Applied Physiology | 1994 | 572 |
| 15 | Protruding aortic atheromas predict stroke in elderly patients undergoing cardiopulmonary bypass: Experience with intraoperative transesophageal echocardiography | Journal of the American College of Cardiology | 1992 | 459 |
| 16 | The mechanisms of action of nonsteroidal antiinflammatory drugs | Arthritis and Rheumatism | 1989 | 407 |
| 17 | Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double-blind, phase 3, non-inferiority trial | The Lancet Gastroenterology and Hepatology | 2016 | 377 |
| 18 | Effect of Darapladib on Major Coronary Events After an Acute Coronary Syndrome | JAMA - Journal of the American Medical Association | 2014 | 375 |
| 19 | COMPARTMENTALIZED RAS/MAPK SIGNALING | Annual Review of Immunology | 2006 | 360 |
| 20 | The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively. | Journal of Clinical Investigation | 1990 | 349 |
| 21 | Relation of Vigorous Exercise to Risk of Atrial Fibrillation | American Journal of Cardiology | 2009 | 320 |
| 22 | Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. | Proceedings of the National Academy of Sciences of the United States of America | 1991 | 317 |
| 23 | Diffusion-Weighted MRI for Quantification of Liver Fibrosis: Preliminary Experience | American Journal of Roentgenology | 2007 | 317 |
| 24 | Thyroid Hormone Action in Cell Culture: Demonstration of Nuclear Receptors in Intact Cells and Isolated Nuclei | Proceedings of the National Academy of Sciences of the United States of America | 1973 | 316 |
| 25 | Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. | Journal of Clinical Investigation | 1988 | 306 |
| 26 | Ataxia with Isolated Vitamin E Deficiency: Heterogeneity of Mutations and Phenotypic Variability in a Large Number of Families | American Journal of Human Genetics | 1998 | 303 |
| 27 | Risk Stratification of Individuals with the Brugada Electrocardiogram: A Meta-Analysis | Journal of Cardiovascular Electrophysiology | 2006 | 303 |
| 28 | High risk for vascular events in patients with protruding aortic atheromas: A prospective study | Journal of the American College of Cardiology | 1994 | 296 |
| 29 | Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism | Nature Immunology | 2016 | 295 |
| 30 | Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 294 |
| 31 | Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. | Journal of Clinical Investigation | 1995 | 290 |
| 32 | Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. | Journal of Immunology | 1992 | 290 |
| 33 | Rearrangement of the transcription factor geneCHOP in myxoid liposarcomas with t(12;16)(q13;p11) | Genes Chromosomes and Cancer | 1992 | 284 |
| 34 | Regulation of gene expression by thyroid hormone. | Journal of Clinical Investigation | 1988 | 275 |
| 35 | Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure. | Journal of Immunology | 1993 | 272 |
| 36 | Cellular and Molecular Basis of the Asbestos-related Diseases | The American Review of Respiratory Disease | 1991 | 260 |
| 37 | Fanconi's Anaemia in the Genetics of Neoplasia | Nature | 1971 | 252 |
| 38 | Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors | Journal of Immunology | 1992 | 250 |
| 39 | The Defibrination Syndrome: Clinical Features and Laboratory Diagnosis | British Journal of Haematology | 1967 | 248 |
| 40 | A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP. | Genes and Development | 1994 | 246 |
| 41 | The Flavanol (−)-Epigallocatechin 3-Gallate Inhibits Amyloid Formation by Islet Amyloid Polypeptide, Disaggregates Amyloid Fibrils, and Protects Cultured Cells against IAPP-Induced Toxicity | Biochemistry | 2010 | 241 |
| 42 | Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides. | Journal of Clinical Investigation | 1998 | 241 |
| 43 | Protruding atherosclerotic plaque in the aortic arch of patients with systemic embolization: A new finding seen by transesophageal echocardiography | American Heart Journal | 1990 | 240 |
| 44 | Flow limitation as a noninvasive assessment of residual upper-airway resistance during continuous positive airway pressure therapy of obstructive sleep apnea. | American Journal of Respiratory and Critical Care Medicine | 1994 | 240 |
| 45 | Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure | Journal of Immunology | 1993 | 240 |
| 46 | IMMUNOLOGIC STUDIES OF THE MAJOR NONIMMUNOGLOBULIN PROTEIN OF AMYLOID | Journal of Experimental Medicine | 1973 | 230 |
| 47 | Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils | Science | 1993 | 229 |
| 48 | Mechanisms of stimulation of interleukin-1 beta and tumor necrosis factor-alpha by Mycobacterium tuberculosis components. | Journal of Clinical Investigation | 1993 | 228 |
| 49 | Disruption of Cholesterol 7α-Hydroxylase Gene in Mice | Journal of Biological Chemistry | 1996 | 227 |
| 50 | Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab | Clinical Cancer Research | 2018 | 222 |
