Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers | Nature Biotechnology | 2015 | 1.1K |
3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures | Advanced Materials | 2015 | 577 |
A light-inducible CRISPR-Cas9 system for control of endogenous gene activation | Nature Chemical Biology | 2015 | 437 |
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy | Nature Communications | 2015 | 307 |
Primary tumor location as a prognostic factor in metastatic colorectal cancer | Journal of the National Cancer Institute | 2015 | 298 |
Quality assessment for Linked Data: A Survey | Semantic Web | 2015 | 274 |
The Patient Acceptable Symptomatic State for the Modified Harris Hip Score and Hip Outcome Score Among Patients Undergoing Surgical Treatment for Femoroacetabular Impingement | American Journal of Sports Medicine | 2015 | 202 |
Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis | Journal of Bone and Mineral Research | 2015 | 163 |
Predicting recurrent mitral regurgitation after mitral valve repair for severe ischemic mitral regurgitation | Journal of Thoracic and Cardiovascular Surgery | 2015 | 145 |
Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering | Acta Biomaterialia | 2015 | 134 |
Adjuvant radioactive iodine therapy is associated with improved survival for patients with intermediate-risk papillary thyroid cancer | Journal of Clinical Endocrinology and Metabolism | 2015 | 128 |
Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site | PLoS Pathogens | 2015 | 116 |
Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells | Journal of Clinical Investigation | 2015 | 104 |
Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators | Genome Research | 2015 | 99 |
Impact of mesothelioma histologic subtype on outcomes in the Surveillance, Epidemiology, and End Results database | Journal of Surgical Research | 2015 | 96 |
Defining the optimal planning target volume in image-guided stereotactic radiosurgery of brain metastases: results of a randomized trial | International Journal of Radiation Oncology Biology Physics | 2015 | 88 |
Cryolipolysis for fat reduction and body contouring: safety and efficacy of current treatment paradigms | Plastic and Reconstructive Surgery | 2015 | 87 |
Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases | Molecular Therapy | 2015 | 86 |
Mutant IDH is sufficient to initiate enchondromatosis in mice | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 80 |
The role of hedgehog signalling in skeletal health and disease | Nature Reviews Rheumatology | 2015 | 76 |
The role of adjuvant therapy in the management of head and neck merkel cell carcinoma: an analysis of 4815 patients | JAMA Otolaryngology - Head and Neck Surgery | 2015 | 74 |
Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage | Nucleic Acids Research | 2015 | 72 |
Impact of extent of surgery on survival for papillary thyroid cancer patients younger than 45 years | Journal of Clinical Endocrinology and Metabolism | 2015 | 70 |
Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients | American Journal of Transplantation | 2015 | 69 |
Enabling functional genomics with genome engineering | Genome Research | 2015 | 67 |