Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells | Cancer Cell | 2014 | 513 |
Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination | Science Translational Medicine | 2014 | 336 |
Epidemiology of aortic aneurysm repair in the United States from 2000 to 2010 | Journal of Vascular Surgery | 2014 | 288 |
Extent of surgery for papillary thyroid cancer is not associated with survival: an analysis of 61,775 patients | Annals of Surgery | 2014 | 246 |
Tumor biology correlates with rates of breast-conserving surgery and pathologic complete response after neoadjuvant chemotherapy for breast cancer: findings from the ACOSOG Z1071 (Alliance) Prospective Multicenter Clinical Trial | Annals of Surgery | 2014 | 244 |
Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector | Nucleic Acids Research | 2014 | 232 |
EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss | Clinical Cancer Research | 2014 | 205 |
Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 193 |
Reduced anticoagulation after mechanical aortic valve replacement: interim results from the prospective randomized on-X valve anticoagulation clinical trial randomized Food and Drug Administration investigational device exemption trial | Journal of Thoracic and Cardiovascular Surgery | 2014 | 168 |
A CRISPR/Cas9-based system for reprogramming cell lineage specification | Stem Cell Reports | 2014 | 147 |
A review of the health impacts of barium from natural and anthropogenic exposure | Environmental Geochemistry and Health | 2014 | 136 |
Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV | Nature | 2014 | 120 |
A joint analysis of metabolomics and genetics of breast cancer | Breast Cancer Research | 2014 | 116 |
Fewer complications result from a video-assisted approach to anatomic resection of clinical stage I lung cancer | Journal of Thoracic and Cardiovascular Surgery | 2014 | 103 |
Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 97 |
Mechanisms and models of spinal cord stimulation for the treatment of neuropathic pain | Brain Research | 2014 | 96 |
Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage | Carcinogenesis | 2014 | 89 |
Simultaneous transcranial magnetic stimulation and single-neuron recording in alert non-human primates | Nature Neuroscience | 2014 | 88 |
Multi-institutional validation of the CAPRA-S score to predict disease recurrence and mortality after radical prostatectomy | European Urology | 2014 | 88 |
Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer | Clinical Cancer Research | 2014 | 84 |
Combined hepatocellular-cholangiocarcinoma: a population-level analysis of an uncommon primary liver tumor | Liver Transplantation | 2014 | 84 |
Papillary thyroid microcarcinoma: an over-treated malignancy? | World Journal of Surgery | 2014 | 81 |
Arthroscopic Repair of Full-Thickness Rotator Cuff Tears With and Without Acromioplasty: Randomized Prospective Trial With 2-Year Follow-up | American Journal of Sports Medicine | 2014 | 80 |
Tissue-engineered cartilage with inducible and tunable immunomodulatory properties | Biomaterials | 2014 | 79 |
CD28 negative T cells: is their loss our gain? | American Journal of Transplantation | 2014 | 79 |