| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Mutations of optineurin in amyotrophic lateral sclerosis | Nature | 2010 | 1,116 |
| 2 | Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development | Nature Medicine | 2015 | 1,089 |
| 3 | Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4 | Immunity | 2014 | 758 |
| 4 | Development of the 21-Gene Assay and Its Application in Clinical Practice and Clinical Trials | Journal of Clinical Oncology | 2008 | 544 |
| 5 | Bone cancers | Cancer | 1995 | 478 |
| 6 | A Multigene Expression Assay to Predict Local Recurrence Risk for Ductal Carcinoma In Situ of the Breast | Journal of the National Cancer Institute | 2013 | 459 |
| 7 | Effects of Tumor Necrosis Factor Alpha on Host Immune Response in Chronic Persistent Tuberculosis: Possible Role for Limiting Pathology | Infection and Immunity | 2001 | 456 |
| 8 | The mammary gland iodide transporter is expressed during lactation and in breast cancer | Nature Medicine | 2000 | 437 |
| 9 | An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype | PLoS Genetics | 2011 | 414 |
| 10 | Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type | Nature Genetics | 2014 | 399 |
| 11 | Rituximab does not improve clinical outcome in a randomized phase 3 trial of CHOP with or without rituximab in patients with HIV-associated non-Hodgkin lymphoma: AIDS-Malignancies Consortium Trial 010 | Blood | 2005 | 397 |
| 12 | Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism | Science Translational Medicine | 2017 | 383 |
| 13 | Nucleus raphe dorsalis in Alzheimer's disease: Neurofibrillary tangles and loss of large neurons | Annals of Neurology | 1985 | 333 |
| 14 | Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients | Science Translational Medicine | 2020 | 312 |
| 15 | A COMPARATIVE STUDY OF MODIFIED BIELSCHOWSKY, BODIAN AND THIOFLAVIN S STAINS ON ALZHEIMER'S NEUROFIBRILLARY TANGLES | Neuropathology and Applied Neurobiology | 1986 | 305 |
| 16 | Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways | Nature Immunology | 2019 | 305 |
| 17 | How I treat the acquired von Willebrand syndrome | Blood | 2011 | 301 |
| 18 | Seroconversion rates following COVID-19 vaccination among patients with cancer | Cancer Cell | 2021 | 297 |
| 19 | Fine Structural Study of Neurofibrillary Changes in a Family with Amyotrophic Lateral Sclerosis | Journal of Neuropathology and Experimental Neurology | 1984 | 283 |
| 20 | Human immunodeficiency virus-1 infection of the nervous system: An autopsy study of 268 adult, pediatric, and fetal brains | Human Pathology | 1991 | 275 |
| 21 | Axicabtagene ciloleucel CD19 CAR-T cell therapy results in high rates of systemic and neurologic remissions in ten patients with refractory large B cell lymphoma including two with HIV and viral hepatitis | Journal of Hematology and Oncology | 2020 | 256 |
| 22 | The Thyrotropin Reference Range Should Remain Unchanged | Journal of Clinical Endocrinology and Metabolism | 2005 | 248 |
| 23 | Parkinson's disease: Neuron loss in the nucleus basalis without concomitant Alzheimer's disease | Annals of Neurology | 1984 | 241 |
| 24 | Principles of Analytic Validation of Immunohistochemical Assays: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center | Archives of Pathology and Laboratory Medicine | 2014 | 240 |
| 25 | Severe Odontogenic Infections, Part 1: Prospective Report | Journal of Oral and Maxillofacial Surgery | 2006 | 230 |
| 26 | Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug | Blood | 2010 | 229 |
| 27 | Age- and Race-Based Serum Thyrotropin Reference Limits | Journal of Clinical Endocrinology and Metabolism | 2010 | 218 |
| 28 | Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts | American Journal of Physiology - Cell Physiology | 2003 | 216 |
| 29 | Bacterial and fungal coinfections in COVID-19 patients hospitalized during the New York City pandemic surge | Infection Control and Hospital Epidemiology | 2021 | 212 |
| 30 | Hydroxychloroquine directly reduces the binding of antiphospholipid antibody–β2-glycoprotein I complexes to phospholipid bilayers | Blood | 2008 | 210 |
| 31 | An Approach for Development of Age-, Gender-, and Ethnicity-Specific Thyrotropin Reference Limits | Thyroid | 2011 | 206 |
| 32 | The association of race and COVID-19 mortality | EClinicalMedicine | 2020 | 206 |
| 33 | A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis | American Journal of Pathology | 2010 | 205 |
| 34 | Flow cytometric measurements of DNA and other cell components in human tumors: A critical appraisal | Human Pathology | 1989 | 203 |
| 35 | Immunocytochemical Co-localization of the Proteasome in Ubiquitinated Structures in Neurodegenerative Diseases and the Elderly | Journal of Neuropathology and Experimental Neurology | 1997 | 197 |
| 36 | Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development | Genome Biology | 2013 | 191 |
| 37 | Hirano bodies and related neuronal inclusions | Neuropathology and Applied Neurobiology | 1994 | 170 |
| 38 | Functional anatomy of the basal ganglia in X‐linked recessive dystonia‐parkinsonism | Annals of Neurology | 2005 | 169 |
| 39 | The Role of the Human Papillomavirus in the Pathogenesis of Schneiderian Inverted Papillomas: An Analytic Overview of the Evidence | Head and Neck Pathology | 2008 | 165 |
| 40 | Pathology Competencies for Medical Education and Educational Cases | Academic Pathology | 2017 | 162 |
| 41 | Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease | Nature Communications | 2019 | 160 |
| 42 | Tumor Microenvironment of Metastasis and Risk of Distant Metastasis of Breast Cancer | Journal of the National Cancer Institute | 2014 | 158 |
| 43 | Expression of Notch pathway proteins correlates with albuminuria, glomerulosclerosis, and renal function | Kidney International | 2010 | 157 |
| 44 | Human Monoclonal Antiphospholipid Antibodies Disrupt the Annexin A5 Anticoagulant Crystal Shield on Phospholipid Bilayers | American Journal of Pathology | 2003 | 155 |
| 45 | The path to a better biomarker: application of a risk management framework for the implementation of PD‐L1 and TILs as immuno‐oncology biomarkers in breast cancer clinical trials and daily practice | Journal of Pathology | 2020 | 154 |
| 46 | Morphologic diversity of long bone adamantinoma. The concept of differentiated (regressing) adamantinoma and its relationship to osteofibrous dysplasia | Cancer | 1989 | 152 |
| 47 | Validation of the Risk Model: High-Risk Classification and Tumor Pattern of Invasion Predict Outcome for Patients with Low-Stage Oral Cavity Squamous Cell Carcinoma | Head and Neck Pathology | 2013 | 152 |
| 48 | Placental pathology of absent and reversed end-diastolic flow in growth-restricted fetuses | Obstetrics and Gynecology | 1997 | 149 |
| 49 | Disease Severity in a Murine Model of Lyme Borreliosis Is Associated with the Genotype of the InfectingBorrelia burgdorferiSensu Stricto Strain | Journal of Infectious Diseases | 2002 | 149 |
| 50 | Impact of Adherence, Knowledge, and Quality of Life on Anticoagulation Control | Annals of Pharmacotherapy | 2005 | 142 |
