| # | Title | Journal | Year | Citations |
|---|
| 1 | Assessment and characterisation of post‐COVID‐19 manifestations | International Journal of Clinical Practice | 2021 | 352 |
| 2 | Synthesis of novel pyrazole derivatives and evaluation of their antidepressant and anticonvulsant activities | European Journal of Medicinal Chemistry | 2009 | 311 |
| 3 | Recent advances in non-ionic surfactant vesicles (niosomes): self-assembly, fabrication, characterization, drug delivery applications and limitations | Drug Delivery | 2014 | 237 |
| 4 | Elicitation of secondary metabolism in actinomycetes | Biotechnology Advances | 2015 | 199 |
| 5 | The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids | Food and Chemical Toxicology | 2011 | 163 |
| 6 | <p>Antiviral potential of green synthesized silver nanoparticles of <em>Lampranthus coccineus</em> and <em>Malephora lutea</em></p> | International Journal of Nanomedicine | 2019 | 156 |
| 7 | Design and Evaluation of Controlled-Release Niosomes and Discomes for Naltrexone Hydrochloride Ocular Delivery | Journal of Pharmaceutical Sciences | 2011 | 133 |
| 8 | Poloxamer-based thermoresponsive ketorolac tromethamine in situ gel preparations: Design, characterisation, toxicity and transcorneal permeation studies | European Journal of Pharmaceutics and Biopharmaceutics | 2017 | 122 |
| 9 | Synthesis, anticancer activity and molecular modeling studies of 1,2,4-triazole derivatives as EGFR inhibitors | European Journal of Medicinal Chemistry | 2018 | 122 |
| 10 | Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies | Bioorganic Chemistry | 2018 | 121 |
| 11 | Recent updates of fluoroquinolones as antibacterial agents | Archiv Der Pharmazie | 2018 | 119 |
| 12 | Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach? | Gut | 2022 | 113 |
| 13 | Spectrophotometric determination of β-adrenergic blocking agents in pharmaceutical formulations | Journal of Pharmaceutical and Biomedical Analysis | 2002 | 106 |
| 14 | MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C | Nature Communications | 2016 | 104 |
| 15 | Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: Synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity | European Journal of Medicinal Chemistry | 2013 | 101 |
| 16 | Corticosteroids in ophthalmology: drug delivery innovations, pharmacology, clinical applications, and future perspectives | Drug Delivery and Translational Research | 2021 | 98 |
| 17 | Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease | RSC Advances | 2020 | 96 |
| 18 | Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/ inflammation pathway | Biomedicine and Pharmacotherapy | 2021 | 90 |
| 19 | EGFR inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and docking studies of novel xanthine derivatives carrying chalcone moiety as hybrid molecules | Bioorganic Chemistry | 2019 | 89 |
| 20 | Characterization of Pseudomonas aeruginosa isolated from clinical and environmental samples in Minia, Egypt: prevalence, antibiogram and resistance mechanisms | Journal of Antimicrobial Chemotherapy | 2007 | 86 |
| 21 | Use of charge-transfer complexation in the spectrophotometric analysis of certain cephalosporins | Talanta | 2001 | 84 |
| 22 | Synthesis and Reactions of Some Fused Oxazinone, Pyrimidinone, Thiopyrimidinone, and Triazinone Derivatives with a Thiophene Ring as Analgesic, Anticonvulsant, and Antiparkinsonian Agents | Monatshefte Für Chemie | 2003 | 83 |
| 23 | Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products | Journal of Controlled Release | 2022 | 78 |
| 24 | Aspernolides F and G, new butyrolactones from the endophytic fungus Aspergillus terreus | Phytochemistry Letters | 2015 | 76 |
| 25 | Natural product diversity from the endophytic fungi of the genusAspergillus | RSC Advances | 2020 | 76 |
| 26 | Protective mechanisms of atorvastatin against doxorubicin-induced hepato-renal toxicity | Biomedicine and Pharmacotherapy | 2014 | 75 |
| 27 | The membrane‐bound O‐acyltransferase domain‐containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B | Hepatology | 2017 | 74 |
| 28 | Molecular targets and anticancer activity of quinoline–chalcone hybrids: literature review | RSC Advances | 2020 | 74 |
| 29 | Synthesis and investigation of anti-inflammatory activity and gastric ulcerogenicity of novel nitric oxide-donating pyrazoline derivatives | European Journal of Medicinal Chemistry | 2009 | 73 |
| 30 | Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose | European Journal of Pharmacology | 2010 | 72 |
| 31 | Conjunctival and corneal tolerability assessment of ocular naltrexone niosomes and their ingredients on the hen's egg chorioallantoic membrane and excised bovine cornea models | International Journal of Pharmaceutics | 2012 | 71 |
| 32 | Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale | RSC Advances | 2020 | 71 |
| 33 | Design, synthesis, antibacterial activity and physicochemical parameters of novel N-4-piperazinyl derivatives of norfloxacin | Bioorganic and Medicinal Chemistry | 2009 | 69 |
| 34 | In-Situ Generation of Differential Sensors that Fingerprint Kinases and the Cellular Response to Their Expression | Journal of the American Chemical Society | 2013 | 69 |
| 35 | Antifungal potential of marine natural products | European Journal of Medicinal Chemistry | 2017 | 69 |
| 36 | Optimization and evaluation of propolis liposomes as a promising therapeutic approach for COVID-19 | International Journal of Pharmaceutics | 2021 | 69 |
| 37 | Formulation and evaluation of ketorolac tromethamine-loaded albumin microspheres for potential intramuscular administration | AAPS PharmSciTech | 2007 | 68 |
| 38 | Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease | Environmental Toxicology and Pharmacology | 2015 | 68 |
| 39 | Molecular characterization of the grape seeds extract’s effect against chemically induced liver cancer: In vivo and in vitro analyses | Scientific Reports | 2018 | 68 |
| 40 | Enhanced skin deposition and delivery of voriconazole using ethosomal preparations | Journal of Liposome Research | 2018 | 67 |
| 41 | Potential of marine natural products against drug-resistant bacterial infections | Lancet Infectious Diseases, The | 2019 | 67 |
| 42 | Preparation and Evaluation of Atorvastatin-Loaded Nanoemulgel on Wound-Healing Efficacy | Pharmaceutics | 2019 | 67 |
| 43 | Metabolomics analysis and biological investigation of three Malvaceae plants | Phytochemical Analysis | 2020 | 66 |
| 44 | Controlled and Continuous Release Ocular Drug Delivery Systems: Pros and Cons | Current Drug Delivery | 2012 | 63 |
| 45 | Synthesis and biological evaluation of novel xanthine derivatives as potential apoptotic antitumor agents | European Journal of Medicinal Chemistry | 2019 | 63 |
| 46 | Pharmacological and natural products diversity of the brown algae genusSargassum | RSC Advances | 2020 | 63 |
| 47 | <p>Prevalence and Some Possible Mechanisms of Colistin Resistance Among Multidrug-Resistant and Extensively Drug-Resistant <em>Pseudomonas aeruginosa</em></p> | Infection and Drug Resistance | 2020 | 63 |
| 48 | Gastroprotective effect of simvastatin against indomethacin-induced gastric ulcer in rats: Role of nitric oxide and prostaglandins | European Journal of Pharmacology | 2009 | 60 |
| 49 | Epigenetic Modifiers Induce Bioactive Phenolic Metabolites in the Marine-Derived Fungus Penicillium brevicompactum | Marine Drugs | 2018 | 59 |
| 50 | Empagliflozin attenuates transient cerebral ischemia/reperfusion injury in hyperglycemic rats via repressing oxidative–inflammatory–apoptotic pathway | Fundamental and Clinical Pharmacology | 2020 | 59 |
