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Department of Biochemistry and Molecular Biology
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top-articles
Department of Biochemistry and Molecular Biology
1.2K
(top 0.1%)
papers
67.2K
(top 0.1%)
citations
113
(top 0.1%)
h
-index
199
(top 0.1%)
g
-index
1.3K
all documents
70.9K
doc citations
4.5K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy
2016
4,701
2
Principles of bioactive lipid signalling: lessons from sphingolipids
Nature Reviews Molecular Cell Biology
2008
2,820
3
The Ceramide-centric Universe of Lipid-mediated Cell Regulation: Stress Encounters of the Lipid Kind
Journal of Biological Chemistry
2002
803
4
Sphingolipid metabolism in cancer signalling and therapy
Nature Reviews Cancer
2018
756
5
Ceramide in apoptosis: an overview and current perspectives
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids
2002
682
6
The complex life of simple sphingolipids
EMBO Reports
2004
591
7
Bioactive sphingolipids: metabolism and function
Journal of Lipid Research
2009
558
8
The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress
Current Molecular Medicine
2016
527
9
The sphingolipid salvage pathway in ceramide metabolism and signaling
Cellular Signalling
2008
506
10
Many Ceramides
Journal of Biological Chemistry
2011
481
11
Cyclin D1, cancer progression, and opportunities in cancer treatment
Journal of Molecular Medicine
2016
477
12
The broken cycle: E2F dysfunction in cancer
Nature Reviews Cancer
2019
475
13
Immune gene discovery by expressed sequence tag analysis of hemocytes and hepatopancreas in the Pacific White Shrimp, Litopenaeus vannamei , and the Atlantic White Shrimp, L. setiferus
Developmental and Comparative Immunology
2001
473
14
The Nucleolin Targeting Aptamer AS1411 Destabilizes
Bcl-2
Messenger RNA in Human Breast Cancer Cells
Cancer Research
2008
444
15
Ceramide synthases at the centre of sphingolipid metabolism and biology
Biochemical Journal
2012
424
16
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
Nature Chemical Biology
2012
402
17
Recent applications of biosurfactants as biological and immunological molecules
Current Opinion in Microbiology
2004
377
18
Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis
Cell
2012
377
19
Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide
Nature
2007
359
20
Ceramide 1-Phosphate Is a Direct Activator of Cytosolic Phospholipase A2
Journal of Biological Chemistry
2004
317
21
The sphingosine kinase 1/sphingosine‐1‐phosphate pathway mediates COX‐2 induction and PGE 2 production in response to TNF‐α
FASEB Journal
2003
313
22
Acid and neutral sphingomyelinases: roles and mechanisms of regulation
Biochemistry and Cell Biology
2004
302
23
The role of ceramide in cell signaling
Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids
1998
279
24
HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma
Cancer Discovery
2015
278
25
Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance
Future Oncology
2010
275
26
Blood sphingolipidomics in healthy humans: impact of sample collection methodology
Journal of Lipid Research
2010
272
27
Long Chain Ceramides Activate Protein Phosphatase-1 and Protein Phosphatase-2A
Journal of Biological Chemistry
1999
271
28
Altered Adipose and Plasma Sphingolipid Metabolism in Obesity
Diabetes
2006
254
29
Serine Palmitoyltransferase Regulates de NovoCeramide Generation during Etoposide-induced Apoptosis
Journal of Biological Chemistry
2000
252
30
Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis
FASEB Journal
2001
248
31
Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase Akt Pathway Mediates Nitric Oxide-Induced Endothelial Cell Migration and Angiogenesis
Molecular and Cellular Biology
2003
248
32
Induction of Antiviral Immunity by Double-Stranded RNA in a Marine Invertebrate
Journal of Virology
2004
248
33
Roles and regulation of secretory and lysosomal acid sphingomyelinase
Cellular Signalling
2009
243
34
CXCL1 Is Critical for Premetastatic Niche Formation and Metastasis in Colorectal Cancer
Cancer Research
2017
243
35
Role for sphingosine kinase 1 in colon carcinogenesis
FASEB Journal
2009
241
36
Ischemic preconditioning protects the mouse liver by inhibition of apoptosis through a caspase-dependent pathway
Hepatology
1999
238
37
Platelets subvert T cell immunity against cancer via GARP-TGFβ axis
Science Immunology
2017
237
38
Molecular Cloning and Characterization of a Human Mitochondrial Ceramidase
Journal of Biological Chemistry
2000
226
39
Antiapoptotic roles of ceramide‐synthase‐6‐generated C
16
‐ceramide
via
selective regulation of the ATF6/ CHOP arm of ER‐stress‐response pathways
FASEB Journal
2010
226
40
Glucosylceramide synthase is an essential regulator of pathogenicity of Cryptococcus neoformans
Journal of Clinical Investigation
2006
219
41
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
EMBO Molecular Medicine
2013
217
42
Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA
Blood
2007
209
43
Roles of Bioactive Sphingolipids in Cancer Biology and Therapeutics
Sub-Cellular Biochemistry
2008
208
44
Roles for C16-ceramide and Sphingosine 1-Phosphate in Regulating Hepatocyte Apoptosis in Response to Tumor Necrosis Factor-α
Journal of Biological Chemistry
2005
205
45
IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment
Cancer Research
2018
203
46
Ceramide Kinase Mediates Cytokine- and Calcium Ionophore-induced Arachidonic Acid Release
Journal of Biological Chemistry
2003
202
47
Defective
FA2H
leads to a novel form of neurodegeneration with brain iron accumulation (NBIA)
Annals of Neurology
2010
202
48
Plasma Membrane Nucleolin Is a Receptor for the Anticancer Aptamer AS1411 in MV4-11 Leukemia Cells
Molecular Pharmacology
2009
197
49
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
Cell Metabolism
2018
197
50
Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition
Nature Medicine
2018
196
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