# | Title | Journal | Year | Citations |
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1 | Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers | Cell | 2012 | 1,038 |
2 | Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. | Circulation Research | 1992 | 896 |
3 | Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide | Free Radical Biology and Medicine | 2003 | 701 |
4 | Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system | Nature Neuroscience | 2010 | 534 |
5 | Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases | Nature Reviews Drug Discovery | 2009 | 527 |
6 | Sarcolemmal Versus Mitochondrial ATP-Sensitive K + Channels and Myocardial Preconditioning | Circulation Research | 1999 | 463 |
7 | Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli | Journal of Neurochemistry | 2005 | 429 |
8 | Endocannabinoid Signaling Negatively Modulates Stress-Induced Activation of the Hypothalamic-Pituitary-Adrenal Axis | Endocrinology | 2004 | 412 |
9 | Localization of cytochromes to the outer membrane of anaerobically grown Shewanella putrefaciens MR-1 | Journal of Bacteriology | 1992 | 400 |
10 | Inhibition of an equilibrative nucleoside transporter by cannabidiol: A mechanism of cannabinoid immunosuppression | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 394 |
11 | Opioid-Induced Cardioprotection Occurs via Glycogen Synthase Kinase β Inhibition During Reperfusion in Intact Rat Hearts | Circulation Research | 2004 | 355 |
12 | The endocannabinoid system in guarding against fear, anxiety and stress | Nature Reviews Neuroscience | 2015 | 350 |
13 | Therapeutic photobiomodulation for methanol-induced retinal toxicity | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 347 |
14 | Pharmacological Evaluation of Cannabinoid Receptor Ligands in a Mouse Model of Anxiety: Further Evidence for an Anxiolytic Role for Endogenous Cannabinoid Signaling | Journal of Pharmacology and Experimental Therapeutics | 2006 | 342 |
15 | Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells | Nature Medicine | 2007 | 326 |
16 | Morphine Mimics the Cardioprotective Effect of Ischemic Preconditioning via a Glibenclamide-Sensitive Mechanism in the Rat Heart | Circulation Research | 1996 | 325 |
17 | The mechanism of action of the Pseudomonas aeruginosa-encoded type III cytotoxin, ExoU | EMBO Journal | 2003 | 321 |
18 | Cultured Rat Microglial Cells Synthesize the Endocannabinoid 2-Arachidonylglycerol, Which Increases Proliferation via a CB2Receptor-Dependent Mechanism | Molecular Pharmacology | 2004 | 320 |
19 | Downregulation of Endocannabinoid Signaling in the Hippocampus Following Chronic Unpredictable Stress | Neuropsychopharmacology | 2005 | 313 |
20 | Epoxides and Soluble Epoxide Hydrolase in Cardiovascular Physiology | Physiological Reviews | 2012 | 302 |
21 | Accumulation of N‐Arachidonoylethanolamine (Anandamide) into Cerebellar Granule Cells Occurs via Facilitated Diffusion | Journal of Neurochemistry | 1997 | 290 |
22 | KATP channels and myocardial preconditioning: an update | American Journal of Physiology - Heart and Circulatory Physiology | 2003 | 286 |
23 | Endogenous cannabinoid signaling is essential for stress adaptation | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 282 |
24 | Cloning and sequence of cymA, a gene encoding a tetraheme cytochrome c required for reduction of iron(III), fumarate, and nitrate by Shewanella putrefaciens MR-1 | Journal of Bacteriology | 1997 | 271 |
25 | Mechanisms of Exercise-Induced Hypoalgesia | Journal of Pain | 2014 | 268 |
26 | Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1) | Journal of Pharmacology and Experimental Therapeutics | 1999 | 265 |
27 | Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling | European Journal of Neuroscience | 2005 | 260 |
28 | Suppression of Amygdalar Endocannabinoid Signaling by Stress Contributes to Activation of the Hypothalamic–Pituitary–Adrenal Axis | Neuropsychopharmacology | 2009 | 257 |
29 | Effects of the KATP channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs. | Circulation | 1994 | 254 |
30 | Immune and Inflammatory Role in Renal Disease | | 2013 | 254 |
31 | Intestinal microbiota determine severity of myocardial infarction in rats | FASEB Journal | 2012 | 251 |
32 | Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate | Cardiovascular Research | 1992 | 246 |
33 | Patterns and functional implications of rare germline variants across 12 cancer types | Nature Communications | 2015 | 243 |
34 | Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry | Neuroscience Letters | 1998 | 238 |
35 | Role for Outer Membrane Cytochromes OmcA and OmcB of Shewanella putrefaciens MR-1 in Reduction of Manganese Dioxide | Applied and Environmental Microbiology | 2001 | 233 |
36 | Ischemic Preconditioning in the Intact Rat Heart Is Mediated by δ1- But Not μ- or κ-Opioid Receptors | Circulation | 1998 | 231 |
37 | Ischemic Preconditioning and Morphine-induced Cardioprotection Involve the Delta (δ)-opioid Receptor in the Intact Rat Heart | Journal of Molecular and Cellular Cardiology | 1997 | 230 |
38 | Neural correlates of high and craving during cocaine self-administration using BOLD fMRI | NeuroImage | 2005 | 220 |
39 | Epoxyeicosatrienoic acids and endothelium-dependent responses | Pflugers Archiv European Journal of Physiology | 2010 | 220 |
40 | Chromium(VI) reductase activity is associated with the cytoplasmic membrane of anaerobically grown Shewanella putrefaciens MR-1 | Journal of Applied Microbiology | 2001 | 214 |
41 | Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment | Journal of Neurochemistry | 2008 | 210 |
42 | Epoxyeicosatrienoic Acids Activate K + Channels in Coronary Smooth Muscle Through a Guanine Nucleotide Binding Protein | Circulation Research | 1997 | 210 |
43 | Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain | Lipids and Lipid Metabolism | 1995 | 208 |
44 | Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice | Neuropharmacology | 2008 | 205 |
45 | Role of the Tetraheme Cytochrome CymA in Anaerobic Electron Transport in Cells of Shewanella putrefaciens MR-1 with Normal Levels of Menaquinone | Journal of Bacteriology | 2000 | 204 |
46 | Ischemic preconditioning in rats: role of mitochondrial KATPchannel in preservation of mitochondrial function | American Journal of Physiology - Heart and Circulatory Physiology | 2000 | 199 |
47 | The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes | Chemistry and Physics of Lipids | 2000 | 195 |
48 | Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks | Psychoneuroendocrinology | 2013 | 193 |
49 | Opioid-Induced Second Window of Cardioprotection | Circulation Research | 1999 | 191 |
50 | A comparison of adenosine-induced cardioprotection and ischemic preconditioning in dogs. Efficacy, time course, and role of KATP channels. | Circulation | 1994 | 190 |