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Institute of Pharmacology and Toxicology
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top-articles
Institute of Pharmacology and Toxicology
58
(top 2%)
papers
1.9K
(top 1%)
citations
20
(top 1%)
h
-index
44
(top 1%)
g
-index
60
all documents
2.0K
doc citations
744
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Hen's egg chorioallantoic membrane test for irritation potential
Food and Chemical Toxicology
1985
352
2
Flavonoids from Hypericum perforatum Show Antidepressant Activity in the Forced Swimming Test
Planta Medica
2000
333
3
Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse Model
Circulation
2014
160
4
Vascular endothelium is critically involved in the hypotensive and hypovolemic actions of atrial natriuretic peptide
Journal of Clinical Investigation
2005
145
5
Plant adaptogens
Phytomedicine
1994
135
6
The HET-CAM test: An alternative to the draize eye test
Food and Chemical Toxicology
1986
118
7
Heart-directed Expression of a Human Cardiac Isoform of cAMP-Response Element Modulator in Transgenic Mice
Journal of Biological Chemistry
2005
79
8
Progressive cardiac hypertrophy and dysfunction in atrial natriuretic peptide receptor (GC-A) deficient mice
British Heart Journal
2002
76
9
Increased effects of C-type natriuretic peptide on cardiac ventricular contractility and relaxation in guanylyl cyclase A-deficient mice
Cardiovascular Research
2002
61
10
HDAC (Histone Deacetylase) Inhibitor Valproic Acid Attenuates Atrial Remodeling and Delays the Onset of Atrial Fibrillation in Mice
Circulation: Arrhythmia and Electrophysiology
2019
49
11
Critical Role of Transcription Factor Cyclic AMP Response Element Modulator in β 1 -Adrenoceptor–Mediated Cardiac Dysfunction
Circulation
2009
38
12
Impaired cardiac contraction and relaxation and decreased expression of sarcoplasmic Ca2+‐ATPase in mice lacking the CREM gene
FASEB Journal
2003
37
13
Stretch-activated two-pore-domain (K2P) potassium channels in the heart: Focus on atrial fibrillation and heart failure
Progress in Biophysics and Molecular Biology
2017
37
14
CREB critically regulates action potential shape and duration in the adult mouse ventricle
American Journal of Physiology - Heart and Circulatory Physiology
2012
28
15
Annexin A4 is a novel direct regulator of adenylyl cyclase type 5
FASEB Journal
2015
27
16
Expression of constitutive nitric oxide synthase in rat and human gastrointestinal tract
Biochimica Et Biophysica Acta - Molecular Cell Research
1999
26
17
Neurotransmitter concentrations and binding at dopamine receptors in rats after maternal exposure to 3,4,3′,4′-tetrachlorobiphenyl: the role of reduced thyroid hormone concentrations
Environmental Toxicology and Pharmacology
2001
25
18
Cardiomyocyte‐specific inactivation of transcription factor CREB in mice
FASEB Journal
2007
25
19
Changes in TSH-immunoreactivity in the pars tuberalis and pars distalis of the fetal rat hypophysis following maternal administration of propylthiouracil and thyroxine
Cell and Tissue Research
1990
23
20
Cardiac expression of the CREM repressor isoform CREM-IbΔC-X in mice leads to arrhythmogenic alterations in ventricular cardiomyocytes
Basic Research in Cardiology
2016
22
21
FATTY ACID ANILIDES AND THE TOXIC OIL SYNDROME
Lancet, The
1982
20
22
Human organ specimen banking — 15 years of experience
Science of the Total Environment
1993
19
23
Intravenous Sphingosylphosphorylcholine Protects Ischemic and Postischemic Myocardial Tissue in a Mouse Model of Myocardial Ischemia/Reperfusion Injury
Mediators of Inflammation
2010
19
24
Transcription factor AP-2α triggers apoptosis in cardiac myocytes
Cell Death and Differentiation
2004
18
25
The hen's egg test (HET)—an alternative toxicity test
British Journal of Dermatology
1986
14
26
Acute systemic vanadate poisoning presenting as cerebrovascular ischemia with prolonged reversible neurological deficits (PRIND)
Clinical Neurology and Neurosurgery
1994
14
27
A novel intronic promoter of the
Crem
gene induces small ICER (smICER) isoforms
FASEB Journal
2014
14
28
Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice
Cardiovascular Research
2022
12
29
Adrenergic Stress Protection of Human iPS Cell-Derived Cardiomyocytes by Fast Kv7.1 Recycling
Frontiers in Physiology
2017
9
30
The first versatile human iPSC-based model of ectopic virus induction allows new insights in RNA-virus disease
Scientific Reports
2020
9
31
Annexin A4 N‐terminal peptide inhibits adenylyl cyclase 5 and limits β‐adrenoceptor‐mediated prolongation of cardiac action potential
FASEB Journal
2020
9
32
Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane
Journal of Cell Science
2022
9
33
Upregulation of SERCA2a following short-term ACE inhibition (by enalaprilat) alters contractile performance and arrhythmogenicity of healthy myocardium in rat
Molecular and Cellular Biochemistry
2015
8
34
The relative merits of polyethyleneglycol as a separating agent in the radioimmunoassay of thyroid hormones
Clinica Chimica Acta
1979
7
35
Distinct Occurrence of Proarrhythmic Afterdepolarizations in Atrial Versus Ventricular Cardiomyocytes: Implications for Translational Research on Atrial Arrhythmia
Frontiers in Pharmacology
2018
7
36
Effects of
Lithospermum officinale
and Related Plants on Hypophyseal and Thyroid Hormones in the Rat
International Journal of Crude Drug Research
1986
5
37
Ouabain treatment is associated with upregulation of phosphatase inhibitor-1 and Na+/Ca2+-exchanger and β-adrenergic sensitization in rat hearts
Biochemical and Biophysical Research Communications
2004
5
38
Inward Rectifier K
+
Currents Contribute to the Proarrhythmic Electrical Phenotype of Atria Overexpressing Cyclic Adenosine Monophosphate Response Element Modulator Isoform CREM‐IbΔC‐X
Journal of the American Heart Association
2020
5
39
Effect ofHelicobacter pylori eradication on cyclooxygenase 2 (COX-2) and inducible nitric oxide synthase (iNOS) expression during gastric adaptation to aspirin (ASA) in humans
Microscopy Research and Technique
2001
4
40
Knockout of ATF1 leads to enhanced cardiac contractility and output
FASEB Journal
2008
4
41
The predictive value of animal experiments in the detection of side effects of drugs on thyroid function
FASEB Journal
1979
3
42
Activation of PKC results in improved contractile effects and Ca
2+
cycling by inhibition of PP2A-B56α
American Journal of Physiology - Heart and Circulatory Physiology
2022
3
43
Induction of ICER is superseded by smICER, challenging the impact of ICER under chronic beta‐adrenergic stimulation
FASEB Journal
2020
2
44
The value of screening methods for the detection of thyroid ‘side effects’
FASEB Journal
1979
1
45
Environmental specimen banking and poisons control — a new challenge
Science of the Total Environment
1993
1
46
The Role of Transcription Factors in the Formation of an Arrhythmogenic Substrate in Congestive Human Heart Failure
Current Medicinal Chemistry
2014
1
47
Impaired myocellular Ca2+ cycling in protein phosphatase PP2A-B56α KO mice is normalized by β-adrenergic stimulation
Journal of Biological Chemistry
2022
1
48
An inexpensive apparatus for simultaneous automatic measurement of oxygen consumption in six small laboratory animals
Journal of Pharmacological Methods
1985
0
49
Embryotoxicity study of propenoic acid, 3-(4-methoxyphenyl)-3-methylbutylester in the wistar rat
Food and Chemical Toxicology
1992
0
50
Increased eNOS expression as a compensatory mechanism reducing β-adrenergic responsiveness?
Cardiovascular Research
2005
0
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