| # | Title | Journal | Year | Citations |
|---|
| 1 | antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters | Nucleic Acids Research | 2015 | 1,764 |
| 2 | Minimum Information about a Biosynthetic Gene cluster | Nature Chemical Biology | 2015 | 715 |
| 3 | Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades | Science | 2015 | 339 |
| 4 | Inhibition of protein aggregation and amyloid formation by small molecules | Current Opinion in Structural Biology | 2015 | 259 |
| 5 | The genetic expectations of a protracted model for the origins of domesticated crops | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 244 |
| 6 | Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology | Current Opinion in Chemical Biology | 2016 | 212 |
| 7 | Three geographically separate domestications of Asian rice | Nature Plants | 2015 | 208 |
| 8 | Graphene in therapeutics delivery: Problems, solutions and future opportunities | European Journal of Pharmaceutics and Biopharmaceutics | 2016 | 197 |
| 9 | What makes a P450 tick? | Trends in Biochemical Sciences | 2013 | 181 |
| 10 | Hyaluronan | Cellular and Molecular Life Sciences | 2007 | 173 |
| 11 | A Systematic Computational Analysis of Biosynthetic Gene Cluster Evolution: Lessons for Engineering Biosynthesis | PLoS Computational Biology | 2014 | 164 |
| 12 | Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes | Journal of the American Chemical Society | 2016 | 164 |
| 13 | Species identification of archaeological marine mammals using collagen fingerprinting | Journal of Archaeological Science | 2014 | 154 |
| 14 | Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium | Journal of Biological Chemistry | 2014 | 153 |
| 15 | Proteome degradation in fossils: investigating the longevity of protein survival in ancient bone | Rapid Communications in Mass Spectrometry | 2014 | 148 |
| 16 | Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose | PLoS Pathogens | 2015 | 128 |
| 17 | New developments in ‘ene’-reductase catalysed biological hydrogenations | Current Opinion in Chemical Biology | 2014 | 123 |
| 18 | Heme Sensor Proteins | Journal of Biological Chemistry | 2013 | 116 |
| 19 | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 112 |
| 20 | Identification of collagen-based materials in cultural heritage | Analyst, The | 2013 | 110 |
| 21 | Ancient collagen reveals evolutionary history of the endemic South American ‘ungulates’ | Proceedings of the Royal Society B: Biological Sciences | 2015 | 106 |
| 22 | Hyaluronan: The Local Solution Conformation Determined by NMR and Computer Modeling is Close to a Contracted Left-handed 4-Fold Helix | Journal of Molecular Biology | 2006 | 102 |
| 23 | Properties of Protein Drug Target Classes | PLoS ONE | 2015 | 97 |
| 24 | Genotype of a historic strain of Mycobacterium tuberculosis | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 95 |
| 25 | Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B 12 ) | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 88 |
| 26 | Updated structure of Drosophila cryptochrome | Nature | 2013 | 83 |
| 27 | A Molecular Phylogeny of Plesiorycteropus Reassigns the Extinct Mammalian Order ‘Bibymalagasia’ | PLoS ONE | 2013 | 79 |
| 28 | Combining histology, stable isotope analysis and ZooMS collagen fingerprinting to investigate the taphonomic history and dietary behaviour of extinct giant tortoises from the Mare aux Songes deposit on Mauritius | Palaeogeography, Palaeoclimatology, Palaeoecology | 2014 | 75 |
| 29 | Proteome degradation in ancient bone: Diagenesis and phylogenetic potential | Palaeogeography, Palaeoclimatology, Palaeoecology | 2014 | 75 |
| 30 | High‐throughput collagen fingerprinting of intact microfaunal remains; a low‐cost method for distinguishing between murine rodent bones | Rapid Communications in Mass Spectrometry | 2016 | 75 |
| 31 | Structural studies on the full‐length LysR‐type regulator TsaR from Comamonas testosteroni T‐2 reveal a novel open conformation of the tetrameric LTTR fold | Molecular Microbiology | 2010 | 72 |
| 32 | Steps towards the synthetic biology of polyketide biosynthesis | FEMS Microbiology Letters | 2014 | 69 |
| 33 | Folate metabolism in human malaria parasites—75 years on | Molecular and Biochemical Parasitology | 2013 | 68 |
| 34 | The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) | Journal of Biological Chemistry | 2011 | 64 |
| 35 | LRIG2 Mutations Cause Urofacial Syndrome | American Journal of Human Genetics | 2013 | 63 |
| 36 | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias | Journal of Biological Chemistry | 2013 | 62 |
| 37 | Synthetic biology advances for pharmaceutical production | Current Opinion in Biotechnology | 2015 | 59 |
| 38 | Reticulated Origin of Domesticated Emmer Wheat Supports a Dynamic Model for the Emergence of Agriculture in the Fertile Crescent | PLoS ONE | 2013 | 59 |
| 39 | Proteomics analysis of ancient food vessel stitching reveals >4000‐year‐old milk protein | Rapid Communications in Mass Spectrometry | 2013 | 58 |
| 40 | Does Microsecond Sugar Ring Flexing Encode 3D-Shape and Bioactivity in the Heparanome? | Biomacromolecules | 2013 | 56 |
| 41 | The outer membrane secretin PilQ from Neisseria meningitidis binds DNA | Microbiology (United Kingdom) | 2007 | 55 |
| 42 | Butyrolactone signalling circuits for synthetic biology | Current Opinion in Chemical Biology | 2015 | 54 |
| 43 | A microbial platform for renewable propane synthesis based on a fermentative butanol pathway | Biotechnology for Biofuels | 2015 | 53 |
| 44 | Expression of recombinant proteins in insect and mammalian cells | Methods | 2018 | 53 |
| 45 | Reorganisation of the Salivary Mucin Network by Dietary Components: Insights from Green Tea Polyphenols | PLoS ONE | 2014 | 53 |
| 46 | GAS2-like proteins mediate communication between microtubules and actin through interaction with end-binding proteins | Journal of Cell Science | 2014 | 51 |
| 47 | Lysine and Arginine Content of Proteins: Computational Analysis Suggests a New Tool for Solubility Design | Molecular Pharmaceutics | 2014 | 51 |
| 48 | Systematic methodology for the development of biocatalytic hydrogen-borrowing cascades: application to the synthesis of chiral α-substituted carboxylic acids from α-substituted α,β-unsaturated aldehydes | Organic and Biomolecular Chemistry | 2015 | 51 |
| 49 | Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase | Journal of Biological Chemistry | 2010 | 48 |
| 50 | Light-driven biocatalytic reduction of α,β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers | Catalysis Science and Technology | 2016 | 48 |
