| # | Title | Journal | Year | Citations |
|---|
| 1 | Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family | Pflugers Archiv European Journal of Physiology | 2004 | 441 |
| 2 | Cytokines as mediators of depression: What can we learn from animal studies? | Neuroscience and Biobehavioral Reviews | 2005 | 405 |
| 3 | Central neurocircuitry associated with emesis | American Journal of Medicine | 2001 | 353 |
| 4 | Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart Failure | Circulation: Heart Failure | 2016 | 265 |
| 5 | Potential Role of Uric Acid in Metabolic Syndrome, Hypertension, Kidney Injury, and Cardiovascular Diseases: Is It Time for Reappraisal? | Current Hypertension Reports | 2013 | 204 |
| 6 | Inhibition of Crm1–p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation | Nature Cell Biology | 2007 | 184 |
| 7 | Comprehensive review of cardiovascular toxicity of drugs and related agents | Medicinal Research Reviews | 2018 | 176 |
| 8 | Origin and Health Impacts of Emissions of Toxic By-Products and Fine Particles from Combustion and Thermal Treatment of Hazardous Wastes and Materials | Environmental Health Perspectives | 2006 | 158 |
| 9 | Inhibition of the Phosphodiesterase 4 (PDE4) Enzyme Reverses Memory Deficits Produced by Infusion of the MEK Inhibitor U0126 into the CA1 Subregion of the Rat Hippocampus | Neuropsychopharmacology | 2004 | 136 |
| 10 | Endocrine Significance of SARS-CoV-2’s Reliance on ACE2 | Endocrinology | 2020 | 120 |
| 11 | Ibuprofen blocks changes in nav 1.7 and 1.8 sodium channels associated with complete freund's adjuvant–induced inflammation in rat | Journal of Pain | 2004 | 116 |
| 12 | PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis | Journal of Hepatology | 2017 | 116 |
| 13 | Involvement of Metalloproteinases 2/9 in Epidermal Growth Factor Receptor Transactivation in Pressure-Induced Myogenic Tone in Mouse Mesenteric Resistance Arteries | Circulation | 2004 | 112 |
| 14 | Second-Generation Antipsychotic Drugs, Olanzapine, Quetiapine, and Clozapine Enhance Neurite Outgrowth in PC12 Cells Via PI3K/AKT, ERK, and Pertussis Toxin-Sensitive Pathways | Journal of Molecular Neuroscience | 2005 | 103 |
| 15 | Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis | Hepatology | 2014 | 103 |
| 16 | Inhibition of glucose transport in PC12 cells by the atypical antipsychotic drugs risperidone and clozapine, and structural analogs of clozapine | Brain Research | 2001 | 102 |
| 17 | Elevated Epidermal Growth Factor Receptor Phosphorylation Induces Resistance Artery Dysfunction in Diabetic db/db Mice | Diabetes | 2008 | 94 |
| 18 | Poly(ADP-Ribose) Polymerase Inhibition Reduces Atherosclerotic Plaque Size and Promotes Factors of Plaque Stability in Apolipoprotein E–Deficient Mice | Circulation | 2007 | 91 |
| 19 | Radical-Containing Ultrafine Particulate Matter Initiates Epithelial-to-Mesenchymal Transitions in Airway Epithelial Cells | American Journal of Respiratory Cell and Molecular Biology | 2013 | 90 |
| 20 | UFP‐101, a Peptide Antagonist Selective for the Nociceptin/Orphanin FQ Receptor | CNS Neuroscience & Therapeutics | 2005 | 88 |
| 21 | Olanzapine produces trophic effects in vitro and stimulates phosphorylation of Akt/PKB, ERK1/2, and the mitogen-activated protein kinase p38 | Brain Research | 2004 | 84 |
| 22 | Constitutive GABAA Receptor Endocytosis Is Dynamin-mediated and Dependent on a Dileucine AP2 Adaptin-binding Motif within the β2 Subunit of the Receptor | Journal of Biological Chemistry | 2003 | 83 |
| 23 | Ocular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated? | Future Microbiology | 2011 | 83 |
| 24 | Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury | Free Radical Biology and Medicine | 2011 | 81 |
| 25 | II. Excitatory amino acid receptors in the brain-gut axis | American Journal of Physiology - Renal Physiology | 2001 | 77 |
| 26 | Cytokine blockade attenuates sympathoexcitation in heart failure: Cross‐talk between nNOS, AT‐1R and cytokines in the hypothalamic paraventricular nucleus | European Journal of Heart Failure | 2008 | 77 |
| 27 | MEK1 activation by PAK: A novel mechanism | Cellular Signalling | 2007 | 73 |
| 28 | In Vivo Changes in the Patterns of Chromatin Structure Associated with the Latent Herpes Simplex Virus Type 1 Genome in Mouse Trigeminal Ganglia Can Be Detected at Early Times after Butyrate Treatment | Journal of Virology | 2007 | 69 |
| 29 | Orexins in rat dorsal motor nucleus of the vagus potently stimulate gastric motor function | American Journal of Physiology - Renal Physiology | 2002 | 68 |
| 30 | Hydrogen sulfide regulates cardiac mitochondrial biogenesis via the activation of AMPK | Journal of Molecular and Cellular Cardiology | 2018 | 64 |
| 31 | Activation of the ACE2/Ang-(1–7)/Mas pathway reduces oxygen–glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction | Neuroscience | 2014 | 62 |
| 32 | Involvement of Local Lamellipodia in Endothelial Barrier Function | PLoS ONE | 2015 | 62 |
| 33 | The MEK1 Scaffolding Protein MP1 Regulates Cell Spreading by Integrating PAK1 and Rho Signals | Molecular and Cellular Biology | 2005 | 60 |
| 34 | Comparison of the behavioral and cardiovascular effects of mephedrone with other drugs of abuse in rats | Psychopharmacology | 2013 | 59 |
| 35 | Cocaine Sensitization: Modulation by Dopamine D2 Receptors | Cerebral Cortex | 2002 | 58 |
| 36 | Tolerance to chronic delta-9-tetrahydrocannabinol (Δ⁹-THC) in rhesus macaques infected with simian immunodeficiency virus. | Experimental and Clinical Psychopharmacology | 2011 | 58 |
| 37 | PKC modulation of GABAA receptor endocytosis and function is inhibited by mutation of a dileucine motif within the receptor β2 subunit | Neuropharmacology | 2005 | 56 |
| 38 | Environmentally persistent free radicals decrease cardiac function before and after ischemia/reperfusion injuryin vivo | Journal of Receptor and Signal Transduction Research | 2011 | 50 |
| 39 | PARP-1 deficiency blocks IL-5 expression through calpain-dependent degradation of STAT-6 in a murine asthma model | Allergy: European Journal of Allergy and Clinical Immunology | 2011 | 50 |
| 40 | Environmentally persistent free radicals decrease cardiac function and increase pulmonary artery pressure | American Journal of Physiology - Heart and Circulatory Physiology | 2012 | 48 |
| 41 | Dopamine Transporter Loss in 6-OHDA Parkinson’s Model Is Unmet by Parallel Reduction in Dopamine Uptake | PLoS ONE | 2012 | 48 |
| 42 | Organization and neurochemistry of vagal preganglionic neurons innervating the lower esophageal sphincter in ferrets | Journal of Comparative Neurology | 2001 | 46 |
| 43 | Identification of neuroprotective compounds of Caenorhabditis elegans dopaminergic neurons against 6-OHDA | Journal of Molecular Neuroscience | 2007 | 46 |
| 44 | Functional Interactions between Cytochromes P450 1A2 and 2B4 Require Both Enzymes to Reside in the Same Phospholipid Vesicle | Journal of Biological Chemistry | 2010 | 43 |
| 45 | Intra-medial prefrontal cortex injection of quinpirole, but not SKF 38393, blocks the acute motor-stimulant response to cocaine in the rat | Psychopharmacology | 2000 | 42 |
| 46 | Combined Angiotensin Receptor–Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure | Journal of the American Heart Association | 2018 | 38 |
| 47 | Inhibition of Cytochrome P450 1A2-Mediated Metabolism and Production of Reactive Oxygen Species by Heme Oxygenase-1 in Rat Liver Microsomes | Drug Metabolism Letters | 2011 | 37 |
| 48 | Extracellular Signal-Regulated Kinase Promotes Rho-Dependent Focal Adhesion Formation by Suppressing p190A RhoGAP | Molecular and Cellular Biology | 2010 | 36 |
| 49 | Nigral GFRα1 Infusion in Aged Rats Increases Locomotor Activity, Nigral Tyrosine Hydroxylase, and Dopamine Content in Synchronicity | Molecular Neurobiology | 2013 | 34 |
| 50 | Effects of storage‐aged red blood cell transfusions on endothelial function in hospitalized patients | Transfusion | 2015 | 33 |
