# | Title | Journal | Year | Citations |
---|
1 | Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging | Alimentary Pharmacology and Therapeutics | 2005 | 522 |
2 | Irregular absorption profiles observed from diclofenac extended release tablets can be predicted using a dissolution test apparatus that mimics in vivo physical stresses | European Journal of Pharmaceutics and Biopharmaceutics | 2008 | 145 |
3 | Replacement therapy with levothyroxine plus triiodothyronine (bioavailable molar ratio 14 : 1) is not superior to thyroxine alone to improve well-being and cognitive performance in hypothyroidism | Clinical Endocrinology | 2004 | 144 |
4 | CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects | Clinical Pharmacology and Therapeutics | 2004 | 118 |
5 | Adverse drug reactions in Germany: direct costs of internal medicine hospitalizations | Pharmacoepidemiology and Drug Safety | 2011 | 102 |
6 | Expression of Adenosine Triphosphate-Binding Cassette (ABC)??Drug Transporters in Peripheral??Blood Cells | Clinical Pharmacokinetics | 2007 | 88 |
7 | Circadian Rhythm of Serum Cortisol after Repeated Inhalation of the New Topical Steroid Ciclesonide | Journal of Clinical Endocrinology and Metabolism | 2002 | 87 |
8 | Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1 | Pharmacogenetics and Genomics | 2008 | 87 |
9 | Expression and activity of vitamin D receptor in the human placenta and in choriocarcinoma BeWo and JEG-3 cell lines | Molecular and Cellular Endocrinology | 2009 | 71 |
10 | A LC–MS/MS method to quantify the novel cholesterol lowering drug ezetimibe in human serum, urine and feces in healthy subjects genotyped for SLCO1B1 | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2006 | 68 |
11 | The Talinolol Double-Peak Phenomenon Is Likely Caused by Presystemic Processing After Uptake from Gut Lumen | Pharmaceutical Research | 2005 | 58 |
12 | Bioavailability of amoxicillin and clavulanic acid from extended release tablets depends on intragastric tablet deposition and gastric emptying | European Journal of Pharmaceutics and Biopharmaceutics | 2008 | 57 |
13 | Oral Absorption of Clarithromycin Is Nearly Abolished by Chronic Comedication of Rifampicin in Foals | Drug Metabolism and Disposition | 2011 | 52 |
14 | Role of the Multidrug Transporter Proteins ABCB1 and ABCC2 in the Diaplacental Transport of Talinolol in the Term Human Placenta | Drug Metabolism and Disposition | 2008 | 46 |
15 | Effect of levothyroxine administration on intestinal P-glycoprotein expression: Consequences for drug disposition* | Clinical Pharmacology and Therapeutics | 2002 | 45 |
16 | Quantitative determination of the macrolide antibiotic tulathromycin in plasma and broncho-alveolar cells of foals using tandem mass spectrometry | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2007 | 42 |
17 | Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins | Clinical Pharmacology and Therapeutics | 2006 | 41 |
18 | Simvastatin does not influence the intestinal P-glycoprotein and MPR2, and the disposition of talinolol after chronic medication in healthy subjects genotyped for the ABCB1, ABCC2 and SLCO1B1 polymorphisms | British Journal of Clinical Pharmacology | 2006 | 40 |
19 | Syncytiotrophoblast Vesicles Show Altered micro-RNA and Haemoglobin Content after Ex-vivo Perfusion of Placentas with Haemoglobin to Mimic Preeclampsia | PLoS ONE | 2014 | 40 |
20 | Quantitative characterization of UDP-glucuronosyltransferase 2B17 in human liver and intestine and its role in testosterone first-pass metabolism | Biochemical Pharmacology | 2018 | 35 |
21 | Clarithromycin Is Absorbed by an Intestinal Uptake Mechanism That Is Sensitive to Major Inhibition by Rifampicin: Results of a Short-Term Drug Interaction Study in Foals | Drug Metabolism and Disposition | 2012 | 34 |
22 | Disposition and Sterol-Lowering Effect of Ezetimibe in Multidrug Resistance-Associated Protein 2-Deficient Rats | Journal of Pharmacology and Experimental Therapeutics | 2006 | 31 |
23 | Ketamine metabolites with antidepressant effects: Fast, economical, and eco-friendly enantioselective separation based on supercritical-fluid chromatography (SFC) and single quadrupole MS detection | Journal of Pharmaceutical and Biomedical Analysis | 2017 | 30 |
24 | In Vivo Probes of Drug Transport: Commonly Used Probe Drugs to Assess Function of Intestinal P-glycoprotein (ABCB1) in Humans | Handbook of Experimental Pharmacology | 2011 | 28 |
25 | Pharmacokinetic and Pharmacodynamic Interactions Between the Immunosuppressant Sirolimus and the Lipid-Lowering Drug Ezetimibe in Healthy Volunteers | Clinical Pharmacology and Therapeutics | 2010 | 22 |
26 | Kinetics of propiverine as assessed by radioreceptor assay in poor and extensive metabolizers of debrisoquine | European Journal of Drug Metabolism and Pharmacokinetics | 1993 | 21 |
27 | The Oral, Once‐Daily Phosphodiesterase 4 Inhibitor Roflumilast Lacks Relevant Pharmacokinetic Interactions With Inhaled Budesonide | Journal of Clinical Pharmacology | 2007 | 21 |
28 | Educating Orally Anticoagulated Patients in Drug Safety | Deutsches Ärzteblatt International | 2014 | 18 |
29 | Disposition kinetics of metronidazole in children | European Journal of Clinical Pharmacology | 1983 | 16 |
30 | Disposition and Antimuscarinic Effects of the Urinary Bladder Spasmolytics Propiverine: Influence of Dosage Forms and Circadian‐Time Rhythms | Journal of Clinical Pharmacology | 2008 | 15 |
31 | A LC–MS/MS method to evaluate the hepatic uptake of the liver-specific magnetic resonance imaging contrast agent gadoxetate (Gd-EOB-DTPA) in vitro and in humans | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2012 | 15 |
32 | Determination of propiverine and its metabolites in rat samples by liquid chromatography–tandem mass spectrometry | Journal of Chromatography A | 2007 | 13 |
33 | Oral absorption of propiverine solution and of the immediate and extended release dosage forms: influence of regioselective intestinal elimination | European Journal of Clinical Pharmacology | 2008 | 13 |
34 | Drug Interactions Between the Immunosuppressant Tacrolimus and the Cholesterol Absorption Inhibitor Ezetimibe in Healthy Volunteers | Clinical Pharmacology and Therapeutics | 2011 | 13 |
35 | Simultaneous quantification of acidic and basic flupirtine metabolites by supercritical fluid chromatography according to European Medicines Agency validation | Journal of Chromatography A | 2019 | 12 |
36 | Anticholinergic properties of propiverine and its metabolites | Die Pharmazie | 1990 | 12 |
37 | Quantitative determination of nystatin in human plasma using LC–MS after inhalative administration in healthy subjects | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2006 | 11 |
38 | Effects of Rifampicin, Dexamethasone, St. John's Wort and Thyroxine on Maternal and Foetal Expression of Abcb1 and Organ Distribution of Talinolol in Pregnant Rats | Basic and Clinical Pharmacology and Toxicology | 2012 | 11 |
39 | Neuropsychiatric manifestations associated with azithromycin in two brothers | European Journal of Clinical Pharmacology | 2010 | 10 |
40 | N‐acetylation and debrisoquine hydroxylation polymorphisms in patients with Gilbert's syndrome. | British Journal of Clinical Pharmacology | 1991 | 9 |
41 | INFLUENCE OF PROPIVERINE ON HEPATIC MICROSOMAL CYTOCHROME P450 ENZYMES IN MALE RATS | Drug Metabolism and Disposition | 2003 | 9 |
42 | Pharmacokinetic Interactions Between Isoniazid and Theophylline in Rats | Journal of Pharmacy and Pharmacology | 2011 | 9 |
43 | Disposition of the cholesterol absorption inhibitor ezetimibe in mdr1a/b (−/−) mice | Journal of Pharmaceutical Sciences | 2007 | 7 |
44 | Influence of a Fat‐Rich Meal on Bioavailability of Extended‐Release and Immediate‐Release Propiverine | Journal of Clinical Pharmacology | 2012 | 6 |
45 | Measurement of abomasal conditions (pH, pressure and temperature) in healthy and diarrheic dairy calves using a wireless ambulatory capsule | Livestock Science | 2017 | 6 |
46 | N-acetylation and debrisoquine type oxidation polymorphism in Caucasians--with reference to age and sex | The International Journal of Clinical Pharmacologyrapy, and Toxicology | 1990 | 6 |
47 | Pharmacokinetics and Pharmacodynamics of Propiverine in Children Aged between 5 and 10 Years with Symptoms of Overactive Bladder | Clinical Pharmacokinetics | 2010 | 5 |
48 | Effects of the P‐Glycoprotein Inhibitor Clarithromycin on the Pharmacokinetics of Intravenous and Oral Trospium Chloride: A 4‐Way Crossover Drug‐Drug Interaction Study in Healthy Subjects | Journal of Clinical Pharmacology | 2019 | 5 |
49 | Potential pharmacokinetic interactions of nocloprost clathrate with retarded theophylline and enteric coated diclofenac after single and repeated premedication in healthy volunteers | The International Journal of Clinical Pharmacologyrapy, and Toxicology | 1993 | 3 |
50 | Relative bioavailability and pharmacodynamic effects of methantheline compared with atropine in healthy subjects | European Journal of Clinical Pharmacology | 2012 | 2 |