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Top Articles

#TitleJournalYearCitations
1Gastric Mucosal Defense and Cytoprotection: Bench to BedsideGastroenterology2008581
2Non-steroidal anti-inflammatory drug-induced small intestinal damage is Toll-like receptor 4 dependentGut2008194
3Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet β cells modulates insulin secretion in ratsBiochemical and Biophysical Research Communications2004178
4Up-Regulation of Cyclooxygenase-2 by Inhibition of Cyclooxygenase-1: A Key to Nonsteroidal Anti-Inflammatory Drug-Induced Intestinal DamageJournal of Pharmacology and Experimental Therapeutics2002154
5Pathogenesis of NSAID-induced gastric damage: Importance of cyclooxygenase inhibition and gastric hypermotilityWorld Journal of Gastroenterology2012150
6Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugsJournal of Physiology (Paris)2001120
7Role of Cyclooxygenase (COX)-1 and COX-2 Inhibition in Nonsteroidal Anti-Inflammatory Drug-Induced Intestinal Damage in Rats: Relation to Various Pathogenic EventsJournal of Pharmacology and Experimental Therapeutics2002119
8ROLES OF ENTEROBACTERIA, NITRIC OXIDE AND NEUTROPHIL IN PATHOGENESIS OF INDOMETHACIN-INDUCED SMALL INTESTINAL LESIONS IN RATSPharmacological Research1999117
9Roles of prostaglandin E-receptor subtypes in gastric and duodenal bicarbonate secretion in ratsGastroenterology1997114
10Roles of Cyclooxygenase, Prostaglandin E2 and EP Receptors in Mucosal Protection and Ulcer Healing in the Gastrointestinal TractCurrent Pharmaceutical Design2018109
11The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel diseaseClinical and Experimental Immunology2010103
12Pathogenic Importance of Intestinal Hypermotility in NSAID-Induced Small Intestinal Damage in RatsDigestion200299
1316,16-Dimethyl prostaglandin E2 inhibits indomethacin-induced small intestinal lesions through EP3 and EP4 receptorsDigestive Diseases and Sciences200290
14Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damageClinica Chimica Acta201087
15Roles of Calcitonin Gene–Related Peptide in Maintenance of Gastric Mucosal Integrity and in Enhancement of Ulcer Healing and AngiogenesisGastroenterology200885
16Expression of vanilloid receptors in rat gastric epithelial cells: role in cellular protectionBiochemical Pharmacology200384
17Role of nitric oxide in regulation of gastric acid secretion in rats: effects of NO donors and NO synthase inhibitorBritish Journal of Pharmacology199877
18Apoptosis, Dysbiosis and Expression of Inflammatory Cytokines are Sequential Events in the Development of 5‐Fluorouracil‐Induced Intestinal Mucositis in MiceBasic and Clinical Pharmacology and Toxicology201777
19Effects of cyclooxygenase-2 selective and nitric oxide-releasing nonsteroidal antiinflammatory drugs on mucosal ulcerogenic and healing responses of the stomachDigestive Diseases and Sciences199875
20Protection against dextran sulfate sodium-induced colitis by microspheres of ellagic acid in ratsLife Sciences200270
21The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2in rat stomachAlimentary Pharmacology and Therapeutics200069
22Protective effect of rebamipide on indomethacin‐induced intestinal damage in ratsJournal of Gastroenterology and Hepatology (Australia)200167
235‐HT3 receptor antagonists ameliorate 5‐fluorouracil‐induced intestinal mucositis by suppression of apoptosis in murine intestinal crypt cellsBritish Journal of Pharmacology201365
24EP 4 receptor mediation of prostaglandin E 2 -stimulated mucus secretion by rabbit gastric epithelial cellsBiochemical Pharmacology199962
25Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptorsAmerican Journal of Physiology - Renal Physiology200762
26Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout miceJournal of Pharmacology and Experimental Therapeutics200162
27Protective Effect of Lafutidine against Indomethacin-Induced Intestinal Ulceration in Rats: Relation to Capsaicin-Sensitive Sensory NeuronsDigestion200061
28Role of Nitric Oxide in Pathogenesis of Aspirin-Induced Gastric Mucosal Damage in RatsDigestion199860
29Prostaglandin EP Receptors Involved in Modulating Gastrointestinal Mucosal IntegrityJournal of Pharmacological Sciences201056
30Roles of Endogenous Prostaglandins and Cyclooxygenase Isozymes in Healing of Indomethacin-Induced Small Intestinal Lesions in RatsJournal of Pharmacology and Experimental Therapeutics200655
31Effect of nitric oxide-releasing aspirin derivative on gastric functional and ulcerogenic responses in rats: comparison with plain aspirinJournal of Pharmacology and Experimental Therapeutics199855
32Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusionLife Sciences200254
33Exacerbation of Nonsteroidal Anti-Inflammatory Drug-Induced Small Intestinal Lesions by Antisecretory Drugs in Rats: The Role of Intestinal MotilityJournal of Pharmacology and Experimental Therapeutics201254
34Probiotic Bifidobacterium bifidum G9‐1 attenuates 5‐fluorouracil‐induced intestinal mucositis in mice via suppression of dysbiosis‐related secondary inflammatory responsesClinical and Experimental Pharmacology and Physiology201752
35Less Damaging Effect of Whisky in Rat Stomachs in Comparison with Pure EthanolDigestion200150
36Potential role of the NADPH oxidase NOX1 in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in miceAmerican Journal of Physiology - Renal Physiology201249
37Facilitation by Endogenous Prostaglandins of Capsaicin-Induced Gastric Protection in Rodents through EP2 and IP ReceptorsJournal of Pharmacology and Experimental Therapeutics200348
38Prostaglandin EP Receptors and Their Roles in Mucosal Protection and Ulcer Healing in the Gastrointestinal TractAdvances in Clinical Chemistry201048
39Saireito (TJ-114), a Japanese Traditional Herbal Medicine, Reduces 5-Fluorouracil-Induced Intestinal Mucositis in Mice by Inhibiting Cytokine-Mediated Apoptosis in Intestinal Crypt CellsPLoS ONE201547
40NSAID-Induced Small Intestinal Damage - Roles of Various Pathogenic FactorsDigestion201546
41G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cellsPharmacological Research201746
42Role of endogenous nitric oxide and prostaglandin in duodenal bicarbonate response induced by mucosal acidification in ratsDigestive Diseases and Sciences200145
43Prostaglandin E Inhibits Indomethacin-Induced Gastric Lesions through EP-1 ReceptorsDigestion200145
44Mechanisms by which endogenous glucocorticoid protects against indomethacin-induced gastric injury in ratsAmerican Journal of Physiology - Renal Physiology200244
45Aggravation by Selective COX-1 and COX-2 Inhibitors of Dextran Sulfate Sodium (DSS)-Induced Colon Lesions in RatsDigestive Diseases and Sciences200744
46The Absence of uPAR Is Associated with the Progression of Dermal FibrosisJournal of Investigative Dermatology200844
47Rebamipide inhibits indomethacin-induced small intestinal injury: Possible involvement of intestinal microbiota modulation by upregulation of α-defensin 5European Journal of Pharmacology201344
48Prevention of NSAID-Induced Small Intestinal Mucosal Injury: Prophylactic Potential of LansoprazoleJournal of Clinical Biochemistry and Nutrition200943
49Role of Serotonin 5-HT<sub>3</sub> Receptors in Intestinal InflammationBiological and Pharmaceutical Bulletin201343
505‐HT3 receptors promote colonic inflammation via activation of substance P/neurokinin‐1 receptors in dextran sulphate sodium‐induced murine colitisBritish Journal of Pharmacology201642