| # | Title | Journal | Year | Citations |
|---|
| 1 | Studies on transformation of Escherichia coli with plasmids | Journal of Molecular Biology | 1983 | 10,861 |
| 2 | Structure of the human class I histocompatibility antigen, HLA-A2 | Nature | 1987 | 3,398 |
| 3 | The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens | Nature | 1987 | 2,363 |
| 4 | Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1 | Nature | 1993 | 2,312 |
| 5 | How eukaryotic transcriptional activators work | Nature | 1988 | 2,060 |
| 6 | DNA Topoisomerases | Annual Review of Biochemistry | 1985 | 1,841 |
| 7 | Regulation of inducible and tissue-specific gene expression | Science | 1987 | 1,719 |
| 8 | The Carbon Dioxide Hydration Activity of Carbonic Anhydrase | Journal of Biological Chemistry | 1971 | 1,666 |
| 9 | Improved single and multicopy lac-based cloning vectors for protein and operon fusions | Gene | 1987 | 1,622 |
| 10 | Structure of influenza haemagglutinin at the pH of membrane fusion | Nature | 1994 | 1,595 |
| 11 | Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide | Nature | 1994 | 1,567 |
| 12 | GAL4-VP16 is an unusually potent transcriptional activator | Nature | 1988 | 1,433 |
| 13 | Identification of two distinct regulatory regions adjacent to the human β-interferon gene | Cell | 1983 | 1,205 |
| 14 | DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression | Cell | 1992 | 1,201 |
| 15 | A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules | Nature | 1988 | 1,161 |
| 16 | Transcriptional activation: A complex puzzle with few easy pieces | Cell | 1994 | 1,155 |
| 17 | Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid | Nature | 1988 | 1,147 |
| 18 | Plasmid screening at high colony density | Gene | 1980 | 1,132 |
| 19 | Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution | Journal of Molecular Biology | 1991 | 1,073 |
| 20 | The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex | Cell | 1992 | 1,035 |
| 21 | Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. | Genes and Development | 1989 | 1,020 |
| 22 | Deletion analysis of GAL4 defines two transcriptional activating segments | Cell | 1987 | 976 |
| 23 | Identification of a putative second T-cell receptor | Nature | 1986 | 950 |
| 24 | Gene regulation by proteins acting nearby and at a distance | Nature | 1986 | 939 |
| 25 | Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. | Journal of Experimental Medicine | 1993 | 888 |
| 26 | Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli | Gene | 1983 | 865 |
| 27 | Identification of self peptides bound to purified HLA-B27 | Nature | 1991 | 865 |
| 28 | Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation | Nature | 1985 | 845 |
| 29 | Transposable Elements in Prokaryotes | Annual Review of Genetics | 1981 | 831 |
| 30 | Interaction between CD4 and class II MHC molecules mediates cell adhesion | Nature | 1987 | 809 |
| 31 | Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro | Cell | 1984 | 804 |
| 32 | A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae | Cell | 1990 | 774 |
| 33 | Specific DNA binding of GAL4, a positive regulatory protein of yeast | Cell | 1985 | 773 |
| 34 | Transcription activation by the adenovirus E1a protein | Nature | 1989 | 768 |
| 35 | Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size | Nature | 1992 | 765 |
| 36 | A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β | Cell | 1987 | 763 |
| 37 | DNA topoisomerase II is required at the time of mitosis in yeast | Cell | 1985 | 761 |
| 38 | A new class of yeast transcriptional activators | Cell | 1987 | 754 |
| 39 | Transcription generates positively and negatively supercoiled domains in the template | Cell | 1988 | 730 |
| 40 | Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus | Nature | 1990 | 726 |
| 41 | PRE-mRNA Splicing | Annual Review of Genetics | 1986 | 724 |
| 42 | The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation | Nature | 1991 | 717 |
| 43 | Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity | Cell | 1994 | 716 |
| 44 | Spiral calcium wave propagation and annihilation in Xenopus laevis oocytes | Science | 1991 | 712 |
| 45 | Specific interactions between proteins implicated in splice site selection and regulated alternative splicing | Cell | 1993 | 711 |
| 46 | Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro | Cell | 1984 | 710 |
| 47 | The class II molecules of the human and murine major histocompatibility complex | Cell | 1984 | 697 |
| 48 | Negative effect of the transcriptional activator GAL4 | Nature | 1988 | 687 |
| 49 | DNA recognition by GAL4: structure of a protein-DNA complex | Nature | 1992 | 685 |
| 50 | Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity | Nature | 1983 | 680 |
