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Top Articles

#TitleJournalYearCitations
1In vivo effects of bisphenol A in laboratory rodent studiesReproductive Toxicology20071,000
2Safety and effectiveness of oral rivaroxaban versus standard anticoagulation for the treatment of symptomatic deep-vein thrombosis (XALIA): an international, prospective, non-interventional studyLancet Haematology,the2016215
3Overview of toxicological aspects of polybrominated diphenyl ethers: A flame-retardant additive in several consumer productsEnvironmental Research2008170
4Developmental toxicity of polychlorinated biphenyls (PCBs): a systematic review of experimental dataArchives of Toxicology2004168
5Characteristics and Pathomechanisms of Endogenously Aged SkinDermatology2007134
6Involvement of the corticotropin-releasing hormone system in the pathogenesis of acne vulgarisBritish Journal of Dermatology2009120
7Sex steroid receptor evolution and signalling in aquatic invertebratesEcotoxicology200798
8European Society of Hypertension position paper on renal denervation 2021Journal of Hypertension202188
9Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathyJournal of Molecular Medicine200873
10Synergistic effects of dexamethasone and quinolones on human-derived tendon cellsInternational Journal of Antimicrobial Agents201071
11Isotretinoin Revisited: Pluripotent Effects on Human Sebaceous Gland CellsJournal of Investigative Dermatology200666
12Off-label medicine use in children and adolescents: results of a population-based study in GermanyBMC Public Health201366
13Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravityJournal of Cellular Biochemistry200857
14Control of blood pressure and risk of mortality in a cohort of older adults: the Berlin Initiative StudyEuropean Heart Journal201954
15Vitamin D receptor haplotypes protect against development of colorectal cancerEuropean Journal of Clinical Pharmacology200752
16Coxsackievirus B3 and adenovirus infections of cardiac cells are efficiently inhibited by vector-mediated RNA interference targeting their common receptorGene Therapy200746
17Drug-induced agranulocytosis in the Berlin case–control surveillance studyEuropean Journal of Clinical Pharmacology201446
18Fixed-dose combination antihypertensive medicationsLancet, The201944
19Regulation of stearoyl-coenzyme A desaturase and fatty acid delta-6 desaturase-2 expression by linoleic acid and arachidonic acid in human sebocytes leads to enhancement of proinflammatory activity but does not affect lipogenesisBritish Journal of Dermatology201141
20Soluble Vascular Endothelial Growth Factor Receptor-1 (sFLT-1) Mediates Downregulation of FLT-1 and Prevents Activated Neutrophils From Women With Preeclampsia From Additional Migration by VEGFCirculation Research200538
21Safety of direct oral anticoagulant exposure during pregnancy: a retrospective cohort studyLancet Haematology,the202038
22Inhibition of the Androgen Receptor by Antisense Oligonucleotides Regulates the Biological Activity of Androgens in SZ95 SebocytesHormone and Metabolic Research200737
23Deficits in pain treatment in nursing homes in Germany: A cross‐sectional studyEuropean Journal of Pain201237
24Rivaroxaban’s Impact on Renal Decline in Patients With Nonvalvular Atrial Fibrillation: A US MarketScan Claims Database AnalysisClinical and Applied Thrombosis/Hemostasis201937
25Antipsychotic Drugs Predominate in Pharmacotherapy of Nursing Home Residents with DementiaPharmacopsychiatry201232
26Bedtime dosing of antihypertensive medications: systematic review and consensus statement: International Society of Hypertension position paper endorsed by World Hypertension League and European Society of HypertensionJournal of Hypertension202232
27Prenatal exposure to diesel exhaust particles and effect on the male reproductive system in miceToxicology200930
28Photodynamic Treatment of Chaoborus crystallinus Larvae with Chlorophyllin Induces Necrosis and ApoptosisPhotochemistry and Photobiology201130
29High Prevalence of Multimorbidity and Polypharmacy in Elderly Patients With Chronic Pain Receiving Home Care are Associated With Multiple Medication-Related ProblemsFrontiers in Pharmacology202130
30Angiotensinogen promoter haplotypes are associated with blood pressure in untreated hypertensivesJournal of Hypertension200427
31XALIA: rationale and design of a non-interventional study of rivaroxaban compared with standard therapy for initial and long-term anticoagulation in deep vein thrombosisThrombosis Journal201427
32The Use of Medication in PregnancyDeutsches Ärzteblatt International201926
33Towards new recommendations to reduce the burden of alcohol-induced hypertension in the European UnionBMC Medicine201724
34Nonpharmacologic Pain Management Interventions in German Nursing Homes: A Cluster Randomized TrialPain Management Nursing201523
35No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester – Evaluation of the national Embryotox cohortReproductive Toxicology201823
36Patient Management Strategies and Long-Term Outcomes in Isolated Distal Deep-Vein Thrombosis versus Proximal Deep-Vein Thrombosis: Findings from XALIATH Open201920
37Individualized Beta-Blocker Treatment for High Blood Pressure Dictated by Medical Comorbidities: Indications Beyond the 2018 European Society of Cardiology/European Society of Hypertension GuidelinesHypertension202220
38Self-reported medication in community-dwelling older adults in Germany: results from the Berlin Initiative StudyBMC Geriatrics202019
39Subgroup Analysis of Patients with Cancer in XALIA: A Noninterventional Study of Rivaroxaban versus Standard Anticoagulation for VTETH Open201718
40Safety of diclofenac use during early pregnancy: A prospective observational cohort studyReproductive Toxicology201818
41Rivaroxaban compared with standard thromboprophylaxis after major orthopaedic surgery: co‐medication interactionsBritish Journal of Clinical Pharmacology201617
42Rethinking 3R strategies: Digging deeper into AnimalTestInfo promotes transparency in in vivo biomedical researchPLoS Biology201717
43XALIA-LEA: An observational study of venous thromboembolism treatment with rivaroxaban and standard anticoagulation in the Asia-Pacific, Eastern Europe, the Middle East, Africa and Latin AmericaThrombosis Research201917
44Therapeutic Reference Ranges for Psychotropic Drugs: A Protocol for Systematic ReviewsFrontiers in Psychiatry202117
45Interventions to address deficits of pharmacological pain management in nursing home residents – A cluster‐randomized trialEuropean Journal of Pain201516
46Small molecules as therapy for uveitis: a selected perspective of new and developing agentsExpert Opinion on Pharmacotherapy201716
47International Consensus on Standardized Clinic Blood Pressure Measurement – A Call to ActionAmerican Journal of Medicine202316
48The importance of protein binding for the in vitro–in vivo extrapolation (IVIVE)—example of ibuprofen, a highly protein-bound substanceArchives of Toxicology201715
49Improving long-term adherence to statin therapy: a qualitative study of GPs’ experiences in primary careBritish Journal of General Practice201815
50Pain management intervention targeting nursing staff and general practitioners: Pain intensity, consequences and clinical relevance for nursing home residentsGeriatrics and Gerontology International201714