| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 2 | Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Nature Genetics | 2011 | 1,676 |
| 3 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 4 | A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay | Nature Genetics | 2010 | 539 |
| 5 | A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease | Nature Medicine | 2020 | 351 |
| 6 | IFATS Collection: The Conditioned Media of Adipose Stromal Cells Protect Against Hypoxia-Ischemia-Induced Brain Damage in Neonatal Rats | Stem Cells | 2009 | 238 |
| 7 | A multicenter, prospective pilot study of gamma knife radiosurgery for mesial temporal lobe epilepsy: Seizure response, adverse events, and verbal memory | Annals of Neurology | 2009 | 236 |
| 8 | Stroke Patients’ Knowledge of Stroke | Stroke | 1997 | 233 |
| 9 | Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing | Clinical Pharmacology and Therapeutics | 2014 | 208 |
| 10 | Recurrent 200-kb deletions of 16p11.2 that include the SH2B1 gene are associated with developmental delay and obesity | Genetics in Medicine | 2010 | 178 |
| 11 | Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography | Epilepsia | 2015 | 177 |
| 12 | Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease | JAMA Neurology | 2014 | 166 |
| 13 | Gerstmann‐Sträussler‐Scheinker Disease and the Indiana Kindred | Brain Pathology | 1995 | 145 |
| 14 | Open-label flexible-dose pilot study to evaluate the safety and tolerability of aripiprazole in patients with psychosis associated with Parkinson's disease | Movement Disorders | 2006 | 138 |
| 15 | The SANTÉ study at 10 years of follow‐up: Effectiveness, safety, and sudden unexpected death in epilepsy | Epilepsia | 2021 | 133 |
| 16 | Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers | Brain | 2019 | 122 |
| 17 | Gene Expression in Temporal Lobe Epilepsy is Consistent with Increased Release of Glutamate by Astrocytes | Molecular Medicine | 2007 | 121 |
| 18 | Human anti- -amyloid antibodies block -amyloid fibril formation and prevent -amyloid-induced neurotoxicity | Brain | 2003 | 119 |
| 19 | Electroanatomic Remodeling of the Left Stellate Ganglion After Myocardial Infarction | Journal of the American College of Cardiology | 2012 | 119 |
| 20 | Adipose stromal cells-secreted neuroprotective media against neuronal apoptosis | Neuroscience Letters | 2009 | 114 |
| 21 | Intravenous Immunoglobulins as a Treatment for Alzheimerʼs Disease | Drugs | 2010 | 101 |
| 22 | Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis | JAMA Neurology | 2018 | 101 |
| 23 | Caffeic acid phenethyl ester prevents neonatal hypoxic-ischaemic brain injury | Brain | 2004 | 99 |
| 24 | Design and Initial Results of a Multi-Phase Randomized Trial of Ceftriaxone in Amyotrophic Lateral Sclerosis | PLoS ONE | 2013 | 93 |
| 25 | Diagnostic utility of video EEG monitoring in paroxysmal events | Acta Neurologica Scandinavica | 1996 | 90 |
| 26 | Pacemaker and Implantable Cardioverter-Defibrillator Use in a US Myotonic Dystrophy Type 1 Population | Journal of Cardiovascular Electrophysiology | 2011 | 83 |
| 27 | Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial | Epilepsia | 2018 | 83 |
| 28 | Deep brain stimulation for epilepsy | Epilepsy and Behavior | 2018 | 81 |
| 29 | AAEE minimonograph #31: The electrodiagnosis of ulnar neuropathy at the elbow | Muscle and Nerve | 1988 | 78 |
| 30 | Increased mortality with left ventricular systolic dysfunction and heart failure in adults with myotonic dystrophy type 1 | American Heart Journal | 2010 | 78 |
| 31 | Minocycline prevents gentamicin-induced ototoxicity by inhibiting p38 MAP kinase phosphorylation and caspase 3 activation | Neuroscience | 2005 | 70 |
| 32 | Early behavioural changes in familial Alzheimer’s disease in the Dominantly Inherited Alzheimer Network | Brain | 2015 | 67 |
| 33 | Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia-induced cerebellar hypoplasia in the Gunn rat | European Journal of Neuroscience | 2005 | 63 |
| 34 | Survival and CTG repeat expansion in adults with myotonic dystrophy type 1 | Muscle and Nerve | 2011 | 60 |
| 35 | Increased β-amyloid deposition in Tg-SWDI transgenic mouse brain following in vivo lead exposure | Toxicology Letters | 2012 | 55 |
| 36 | Parietal Lobe Epilepsy | Journal of Clinical Neurophysiology | 2012 | 52 |
| 37 | Pharmacologic treatment of cognition in Alzheimer's dementia | Neurology | 1998 | 50 |
| 38 | Adipose stromal cells-conditional medium protected glutamate-induced CGNs neuronal death by BDNF | Neuroscience Letters | 2009 | 50 |
| 39 | The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease | JAMA Neurology | 2016 | 49 |
| 40 | Age-Specific Incidence Rates for Dementia and Alzheimer Disease in NIA-LOAD/NCRAD and EFIGA Families | JAMA Neurology | 2014 | 48 |
| 41 | Standardized Treatment of Neonatal Status Epilepticus Improves Outcome | Journal of Child Neurology | 2016 | 48 |
| 42 | Novel verbal fluency scores and structural brain imaging for prediction of cognitive outcome in mild cognitive impairment | Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring | 2016 | 47 |
| 43 | Unruptured intracranial aneurysms in the Familial Intracranial Aneurysm and International Study of Unruptured Intracranial Aneurysms cohorts: differences in multiplicity and location | Journal of Neurosurgery | 2012 | 45 |
| 44 | Intracranial Blastomycoma | Medicine (United States) | 1987 | 42 |
| 45 | Rivastigmine: an open-label, observational study of safety and effectiveness in treating patients with Alzheimer's disease for up to 5 years | BMC Geriatrics | 2005 | 42 |
| 46 | Identification of a Novel Locus for Febrile Seizures and Epilepsy on Chromosome 21q22 | Epilepsia | 2006 | 42 |
| 47 | Injection of Autologous Muscle Stem Cells (Myoblasts) for the Treatment of Vocal Fold Paralysis: A Pilot Study | Laryngoscope | 2007 | 41 |
| 48 | Rarity of the Alzheimer Disease–ProtectiveAPPA673T Variant in the United States | JAMA Neurology | 2015 | 41 |
| 49 | 3,4‐diaminopyridine base effectively treats the weakness of Lambert‐Eaton myasthenia | Muscle and Nerve | 2018 | 40 |
| 50 | Treatment of Status Epilepticus With Electroconvulsive Therapy | Journal of ECT | 2007 | 37 |
