# | Title | Journal | Year | Citations |
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1 | Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C | Nature Genetics | 2009 | 2,124 |
2 | JSH Consensus-Based Clinical Practice Guidelines for the Management of Hepatocellular Carcinoma: 2014 Update by the Liver Cancer Study Group of Japan | Liver Cancer | 2014 | 512 |
3 | Japan Society of Hepatology guidelines for sarcopenia in liver disease (1st edition): Recommendation from the working group for creation of sarcopenia assessment criteria | Hepatology Research | 2016 | 463 |
4 | Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system | International Immunology | 2008 | 451 |
5 | JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure ― Digest Version ― | Circulation Journal | 2019 | 446 |
6 | Phase III study comparing oxaliplatin plus S-1 with cisplatin plus S-1 in chemotherapy-naïve patients with advanced gastric cancer | Annals of Oncology | 2015 | 417 |
7 | Guidelines for the Management ofHelicobacter pyloriInfection in Japan: 2009 Revised Edition | Helicobacter | 2010 | 416 |
8 | Esophageal Disorders | Gastroenterology | 2016 | 411 |
9 | Impact of Dual Lipid-Lowering Strategy With Ezetimibe and Atorvastatin on Coronary Plaque Regression in Patients With Percutaneous Coronary Intervention | Journal of the American College of Cardiology | 2015 | 352 |
10 | Dietary Risk Factors for Inflammatory Bowel Disease | Inflammatory Bowel Diseases | 2005 | 338 |
11 | JCS 2018 Guideline on Diagnosis and Treatment of Acute Coronary Syndrome | Circulation Journal | 2019 | 324 |
12 | Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer | Clinical Cancer Research | 2009 | 296 |
13 | Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy | Neuron | 2012 | 296 |
14 | Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): a multicentre phase 2 trial | Lancet Haematology,the | 2015 | 261 |
15 | Recommendations for Uniform Definitions of Surgical Techniques for Malignant Pleural Mesothelioma: A Consensus Report of the International Association for the Study of Lung Cancer International Staging Committee and the International Mesothelioma Interest Group | Journal of Thoracic Oncology | 2011 | 249 |
16 | Neuromyelitis optica: Passive transfer to rats by human immunoglobulin | Biochemical and Biophysical Research Communications | 2009 | 233 |
17 | High uric acid directly inhibits insulin signalling and induces insulin resistance | Biochemical and Biophysical Research Communications | 2014 | 210 |
18 | International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values | Diabetology International | 2012 | 202 |
19 | Intracellular Role for Sphingosine Kinase 1 in Intestinal Adenoma Cell Proliferation | Molecular and Cellular Biology | 2006 | 201 |
20 | Risk and prevention of graft failure in patients with preexisting donor-specific HLA antibodies undergoing unmanipulated haploidentical SCT | Bone Marrow Transplantation | 2012 | 188 |
21 | Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis | Inflammatory Bowel Diseases | 2012 | 180 |
22 | Overweight and obesity increase the risk for liver cancer in patients with liver cirrhosis and long-term oral supplementation with branched-chain amino acid granules inhibits liver carcinogenesis in heavier patients with liver cirrhosis | Hepatology Research | 2006 | 179 |
23 | Gastrointestinal mucosal barrier function and diseases | Journal of Gastroenterology | 2016 | 173 |
24 | The IASLC Mesothelioma Staging Project: Proposals for the M Descriptors and for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Mesothelioma | Journal of Thoracic Oncology | 2016 | 172 |
25 | Bronchiolitis Obliterans Syndrome (BOS), Bronchiolitis Obliterans Organizing Pneumonia (BOOP), and Other Late-Onset Noninfectious Pulmonary Complications following Allogeneic Hematopoietic Stem Cell Transplantation | Biology of Blood and Marrow Transplantation | 2007 | 170 |
26 | Effect of Dexmedetomidine on Mortality and Ventilator-Free Days in Patients Requiring Mechanical Ventilation With Sepsis | JAMA - Journal of the American Medical Association | 2017 | 170 |
27 | Changes in the expression of claudins in active ulcerative colitis | Journal of Gastroenterology and Hepatology (Australia) | 2008 | 162 |
28 | Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis | Biochimica Et Biophysica Acta - Molecular Cell Research | 2009 | 160 |
29 | A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RARα transcript after consolidation therapy: The Japan Adult Leukemia Study Group (JALSG) APL97 study | Blood | 2007 | 158 |
30 | Acoustic Radiation Force Impulse Elastography for fibrosis evaluation in patients with chronic hepatitis C: An international multicenter study | European Journal of Radiology | 2012 | 156 |
31 | Endothelial Cells Support Survival, Proliferation, and Neuronal Differentiation of Transplanted Adult Ischemia-Induced Neural Stem/Progenitor Cells After Cerebral Infarction | Stem Cells | 2009 | 154 |
32 | Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid) | Clinica Chimica Acta | 2005 | 150 |
33 | Elevated serum myostatin level is associated with worse survival in patients with liver cirrhosis | Journal of Cachexia, Sarcopenia and Muscle | 2017 | 150 |
34 | Association between hemoglobin variability, serum ferritin levels, and adverse events/mortality in maintenance hemodialysis patients | Kidney International | 2014 | 142 |
35 | Etiology of liver cirrhosis in Japan: a nationwide survey | Journal of Gastroenterology | 2010 | 130 |
36 | Epidemiology of Functional Gastrointestinal Disorders in Japan and in the World | Journal of Neurogastroenterology and Motility | 2015 | 130 |
37 | High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 130 |
38 | Localization of oxidized phosphatidylcholine in nonalcoholic fatty liver disease: Impact on disease progression | Hepatology | 2006 | 129 |
39 | Bone Marrow Mononuclear Cells Promote Proliferation of Endogenous Neural Stem Cells Through Vascular Niches After Cerebral Infarction | Stem Cells | 2010 | 129 |
40 | Apathy and Depression in Parkinson Disease | Journal of Geriatric Psychiatry and Neurology | 2010 | 126 |
41 | The efficacy of ursodeoxycholic acid and bezafibrate combination therapy for primary biliary cirrhosis: A prospective, multicenter study | Hepatology Research | 2008 | 123 |
42 | Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout | Clinical and Experimental Nephrology | 2014 | 123 |
43 | Ischemia-Induced Neural Stem/Progenitor Cells in the Pia Mater Following Cortical Infarction | Stem Cells and Development | 2011 | 122 |
44 | Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients | Aids | 2005 | 121 |
45 | AZD2171 Shows Potent Antitumor Activity Against Gastric Cancer Over-Expressing Fibroblast Growth Factor Receptor 2/Keratinocyte Growth Factor Receptor | Clinical Cancer Research | 2007 | 121 |
46 | Expression of Hepatoma-Derived Growth Factor Is Correlated with Lymph Node Metastasis and Prognosis of Gastric Carcinoma | Clinical Cancer Research | 2006 | 120 |
47 | Adaptive response of the heart to long-term anemia induced by iron deficiency | American Journal of Physiology - Heart and Circulatory Physiology | 2009 | 120 |
48 | MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain | Cell Reports | 2015 | 120 |
49 | GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis | Inflammation Research | 2011 | 119 |
50 | Importance of Kupffer Cells in the Development of Acute Liver Injuries in Mice | International Journal of Molecular Sciences | 2014 | 119 |