| # | Title | Journal | Year | Citations |
|---|
| 1 | Cerebral organoids model human brain development and microcephaly | Nature | 2013 | 3,889 |
| 2 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 4 | Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression | Nature Genetics | 2018 | 2,224 |
| 5 | Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals | Nature Genetics | 2018 | 1,835 |
| 6 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 7 | Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions | Nature Neuroscience | 2019 | 1,589 |
| 8 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 9 | Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans | Nature | 2009 | 1,405 |
| 10 | Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection | Nature Genetics | 2018 | 1,332 |
| 11 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 12 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 13 | A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants | Nature Genetics | 2016 | 1,167 |
| 14 | Cholangiocarcinoma 2020: the next horizon in mechanisms and management | Nature Reviews Gastroenterology and Hepatology | 2020 | 1,155 |
| 15 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 16 | Genetic mechanisms of critical illness in COVID-19 | Nature | 2021 | 1,014 |
| 17 | Runs of Homozygosity in European Populations | American Journal of Human Genetics | 2008 | 958 |
| 18 | Resolving the fibrotic niche of human liver cirrhosis at single-cell level | Nature | 2019 | 946 |
| 19 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 20 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 21 | Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses | Nature Genetics | 2016 | 870 |
| 22 | RNA buffers the phase separation behavior of prion-like RNA binding proteins | Science | 2018 | 837 |
| 23 | GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment | Science | 2013 | 750 |
| 24 | Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways | Nature Genetics | 2012 | 746 |
| 25 | Eleven grand challenges in single-cell data science | Genome Biology | 2020 | 742 |
| 26 | Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease | Nature Genetics | 2010 | 692 |
| 27 | Genome Architecture: Domain Organization of Interphase Chromosomes | Cell | 2013 | 659 |
| 28 | Single-Cell Dynamics of Genome-Nuclear Lamina Interactions | Cell | 2013 | 609 |
| 29 | Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study | Lancet, The | 2016 | 607 |
| 30 | Genome-wide association studies establish that human intelligence is highly heritable and polygenic | Molecular Psychiatry | 2011 | 571 |
| 31 | A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness | PLoS Genetics | 2014 | 553 |
| 32 | Multi-ethnic genome-wide association study for atrial fibrillation | Nature Genetics | 2018 | 552 |
| 33 | DNA methylation aging clocks: challenges and recommendations | Genome Biology | 2019 | 552 |
| 34 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Nature Genetics | 2019 | 549 |
| 35 | Rare and low-frequency coding variants alter human adult height | Nature | 2017 | 544 |
| 36 | RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection | Molecular Cell | 2013 | 543 |
| 37 | Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 | Nature Genetics | 2008 | 542 |
| 38 | Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 530 |
| 39 | E-cadherin–integrin crosstalk in cancer invasion and metastasis | Journal of Cell Science | 2013 | 525 |
| 40 | Genome-wide association study identifies five loci associated with lung function | Nature Genetics | 2010 | 518 |
| 41 | A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 | Nature Genetics | 2008 | 514 |
| 42 | Timing, rates and spectra of human germline mutation | Nature Genetics | 2016 | 502 |
| 43 | Runs of homozygosity: windows into population history and trait architecture | Nature Reviews Genetics | 2018 | 497 |
| 44 | Dynamic landscape and regulation of RNA editing in mammals | Nature | 2017 | 495 |
| 45 | Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells | PLoS Genetics | 2008 | 494 |
| 46 | Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk | Nature Genetics | 2017 | 492 |
| 47 | Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders | Nature Neuroscience | 2018 | 490 |
| 48 | Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination | Molecular Cell | 2010 | 485 |
| 49 | Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function | Nature Communications | 2018 | 484 |
| 50 | Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture | Nature | 2015 | 483 |
