| # | Title | Journal | Year | Citations |
|---|
| 1 | Levosimendan: Molecular mechanisms and clinical implications | International Journal of Cardiology | 2012 | 256 |
| 2 | Melatonin and circadian biology in human cardiovascular disease | Journal of Pineal Research | 2010 | 185 |
| 3 | Decreased nocturnal melatonin levels during acute myocardial infarction | Journal of Pineal Research | 2002 | 96 |
| 4 | Therapeutic Algorithm for Use of Melatonin in Patients With COVID-19 | Frontiers in Medicine | 2020 | 82 |
| 5 | Cardiogenic shock after primary percutaneous coronary intervention: Effects of levosimendan compared with dobutamine on haemodynamics | European Journal of Heart Failure | 2006 | 75 |
| 6 | Light/dark patterns of interleukin-6 in relation to the pineal hormone melatonin in patients with acute myocardial infarction | Cytokine | 2004 | 69 |
| 7 | Effect of intravenous and intracoronary melatonin as an adjunct to primary percutaneous coronary intervention for acute ST‐elevation myocardial infarction: Results of the Melatonin Adjunct in the acute myocaRdial Infarction treated with Angioplasty trial | Journal of Pineal Research | 2017 | 66 |
| 8 | The role of melatonin in acute myocardial infarction | Frontiers in Bioscience - Landmark | 2012 | 64 |
| 9 | Elevated levels of oxidized low-density lipoprotein and impaired nocturnal synthesis of melatonin in patients with myocardial infarction | Atherosclerosis | 2005 | 63 |
| 10 | Melatonin Inhibits COVID-19-induced Cytokine Storm by Reversing Aerobic Glycolysis in Immune Cells: A Mechanistic Analysis | Medicine in Drug Discovery | 2020 | 61 |
| 11 | Usefulness of Early Treatment With Melatonin to Reduce Infarct Size in Patients With ST-Segment Elevation Myocardial Infarction Receiving Percutaneous Coronary Intervention (From the Melatonin Adjunct in the Acute Myocardial Infarction Treated With Angioplasty Trial) | American Journal of Cardiology | 2017 | 59 |
| 12 | Repetitive use of levosimendan for treatment of chronic advanced heart failure: Clinical evidence, practical considerations, and perspectives: An expert panel consensus | International Journal of Cardiology | 2014 | 56 |
| 13 | Prognostic Value of Malondialdehyde Serum Levels in Severe Sepsis: A Multicenter Study | PLoS ONE | 2013 | 49 |
| 14 | The impact of frailty in older patients with non-ischaemic cardiomyopathy after implantation of cardiac resynchronization therapy defibrillator | Europace | 2015 | 47 |
| 15 | Management and outcomes in chronic thromboembolic pulmonary hypertension: From expert centers to a nationwide perspective | International Journal of Cardiology | 2016 | 46 |
| 16 | β-Blockers, Cocaine, and the Unopposed α-Stimulation Phenomenon | Journal of Cardiovascular Pharmacology and Therapeutics | 2017 | 46 |
| 17 | Relation of Growth-Differentiation Factor 15 to Left Ventricular Remodeling in ST-Segment Elevation Myocardial Infarction | American Journal of Cardiology | 2011 | 45 |
| 18 | Current role of ischemia-modified albumin in routine clinical practice | Biomarkers | 2010 | 41 |
| 19 | Circulating pregnancy-associated plasma protein A is not an early marker of acute myocardial infarction | Clinical Biochemistry | 2005 | 40 |
| 20 | Relation of nocturnal melatonin levels to serum matrix metalloproteinase-9 concentrations in patients with myocardial infarction | Thrombosis Research | 2007 | 39 |
| 21 | Effects of levosimendan versus dobutamine on left ventricular diastolic function in patients with cardiogenic shock after primary angioplasty | International Journal of Cardiology | 2008 | 37 |
| 22 | Interatrial block and atrial remodeling assessed using speckle tracking echocardiography | BMC Cardiovascular Disorders | 2018 | 36 |
| 23 | Left ventricular global longitudinal systolic strain predicts adverse remodeling and subsequent cardiac events in patients with acute myocardial infarction treated with primary percutaneous coronary intervention | International Journal of Cardiovascular Imaging | 2015 | 34 |
| 24 | Valve Calcification in Aortic Stenosis: Etiology and Diagnostic Imaging Techniques | BioMed Research International | 2017 | 34 |
| 25 | The potential usefulness of serum melatonin level to predict heart failure in patients with hypertensive cardiomyopathy | International Journal of Cardiology | 2014 | 32 |
| 26 | Utility of Levosimendan, a New Calcium Sensitizing Agent, in the Treatment of Cardiogenic Shock Due to Myocardial Stunning in Patients With ST-Elevation Myocardial Infarction: A Series of Cases | Journal of Clinical Pharmacology | 2005 | 30 |
| 27 | Advanced interatrial block is a surrogate for left atrial strain reduction which predicts atrial fibrillation and stroke | Annals of Noninvasive Electrocardiology | 2019 | 29 |
| 28 | Myocardial ischemia-reperfusion injury: Possible role of melatonin | World Journal of Cardiology | 2010 | 29 |
| 29 | Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection | Cellular and Molecular Life Sciences | 2022 | 28 |
| 30 | Soluble CD40 ligand:interleukin-10 ratio predicts in-hospital adverse events in patients with ST-segment elevation myocardial infarction | Thrombosis Research | 2007 | 26 |
| 31 | Efficacy and safety of intermittent repeated levosimendan infusions in advanced heart failure patients: the LAICA study | ESC Heart Failure | 2021 | 26 |
| 32 | Plasticity of glucose metabolism in activated immune cells: advantages for melatonin inhibition of COVID-19 disease | Melatonin Research | 2020 | 25 |
| 33 | Prognostic Value of Nocturnal Melatonin Levels as a Novel Marker in Patients With ST-Segment Elevation Myocardial Infarction | American Journal of Cardiology | 2006 | 24 |
| 34 | Increased heart rate and atherosclerosis: Potential implications of ivabradine therapy | World Journal of Cardiology | 2011 | 22 |
| 35 | Study Design and Rationale of “A Multicenter, Open-Labeled, Randomized Controlled Trial Comparing MIdazolam Versus MOrphine in Acute Pulmonary Edema”: MIMO Trial | Cardiovascular Drugs and Therapy | 2017 | 21 |
| 36 | Pharmacologic Treatment of Heart Failure due to Ventricular Dysfunction by Myocardial Stunning | American Journal of Cardiovascular Drugs | 2006 | 20 |
| 37 | Melatonin as a putative protection against myocardial injury in COVID-19 infection | Expert Review of Clinical Pharmacology | 2020 | 20 |
| 38 | Current role of myeloperoxidase in routine clinical practice | Expert Review of Cardiovascular Therapy | 2011 | 18 |
| 39 | Melatonin and cardioprotection in the acute myocardial infarction: A promising cardioprotective agent | International Journal of Cardiology | 2012 | 17 |
| 40 | Rationale and Design of a Randomized, Double-Blind, Placebo Controlled Multicenter Trial to Study Efficacy, Security, and Long Term Effects of Intermittent Repeated Levosimendan Administration in Patients with Advanced Heart Failure: LAICA study | Cardiovascular Drugs and Therapy | 2013 | 17 |
| 41 | Saharan Dust Events in the Dust Belt -Canary Islands- and the Observed Association with in-Hospital Mortality of Patients with Heart Failure | Journal of Clinical Medicine | 2020 | 17 |
| 42 | Clinical and echocardiographic outcomes of transcatheter mitral valve repair in atrial functional mitral regurgitation | International Journal of Cardiology | 2021 | 17 |
| 43 | Usefulness of Intraplatelet Melatonin Levels to Predict Angiographic No-Reflow After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction | American Journal of Cardiology | 2010 | 16 |
| 44 | Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices | Europace | 2020 | 16 |
| 45 | A case-control study of melatonin receptor type 1A polymorphism and acute myocardial infarction in a Spanish population | Journal of Pineal Research | 2011 | 15 |
| 46 | Safety threshold of R-wave amplitudes in patients with implantable cardioverter defibrillator | Heart | 2016 | 15 |
| 47 | Midazolam versus morphine in acute cardiogenic pulmonary oedema: results of a multicentre, open‐label, randomized controlled trial | European Journal of Heart Failure | 2022 | 15 |
| 48 | Serum ferritin and acute coronary syndrome: A strong prognostic factor? | International Journal of Cardiology | 2011 | 14 |
| 49 | Ventilatory efficiency predicts adverse cardiovascular events in asymptomatic patients with severe aortic stenosis and preserved ejection fraction | International Journal of Cardiology | 2014 | 14 |
| 50 | Elevated circulating soluble form of CD40 ligand in patients with cardiac syndrome X | Atherosclerosis | 2010 | 13 |
