| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Geometric Control of Cell Life and Death | Science | 1997 | 4,452 |
| 2 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015 | JAMA Oncology | 2017 | 4,441 |
| 3 | Reconstituting Organ-Level Lung Functions on a Chip | Science | 2010 | 3,349 |
| 4 | Circulating mitochondrial DAMPs cause inflammatory responses to injury | Nature | 2010 | 3,084 |
| 5 | Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors | Science Translational Medicine | 2011 | 2,992 |
| 6 | The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After | Surgery | 2017 | 2,851 |
| 7 | Global Surgery 2030: evidence and solutions for achieving health, welfare, and economic development | Lancet, The | 2015 | 2,625 |
| 8 | Genomic responses in mouse models poorly mimic human inflammatory diseases | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 2,578 |
| 9 | Microfluidic organs-on-chips | Nature Biotechnology | 2014 | 2,578 |
| 10 | Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart | Nature Medicine | 2008 | 2,430 |
| 11 | Soft Lithography in Biology and Biochemistry | Annual Review of Biomedical Engineering | 2001 | 2,406 |
| 12 | Role of cell shape in growth control | Nature | 1978 | 2,372 |
| 13 | Thalidomide is an inhibitor of angiogenesis. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 2,320 |
| 14 | Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 2,297 |
| 15 | Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor | Cell | 1998 | 2,275 |
| 16 | Role of angiogenesis in tumor growth and metastasis | Seminars in Oncology | 2002 | 2,193 |
| 17 | Clinical Applications of Research on Angiogenesis | New England Journal of Medicine | 1995 | 2,145 |
| 18 | The SCARE 2018 statement: Updating consensus Surgical CAse REport (SCARE) guidelines | International Journal of Surgery | 2018 | 2,127 |
| 19 | An estimation of the global volume of surgery: a modelling strategy based on available data | Lancet, The | 2008 | 2,079 |
| 20 | Quality of Life and Satisfaction with Outcome among Prostate-Cancer Survivors | New England Journal of Medicine | 2008 | 2,059 |
| 21 | Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression | Journal of Experimental Medicine | 2007 | 2,043 |
| 22 | Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis | Cell | 2014 | 2,038 |
| 23 | Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer | Nature Medicine | 2004 | 1,862 |
| 24 | Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells | Nature Genetics | 2003 | 1,845 |
| 25 | A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering | Biomaterials | 2003 | 1,837 |
| 26 | Induction of angiogenesis during the transition from hyperplasia to neoplasia | Nature | 1989 | 1,793 |
| 27 | Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression | Nature Medicine | 1995 | 1,758 |
| 28 | 2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines | Annals of Thoracic Surgery | 2011 | 1,756 |
| 29 | Development and Validation of the International Knee Documentation Committee Subjective Knee Form | American Journal of Sports Medicine | 2001 | 1,716 |
| 30 | Soluble endoglin contributes to the pathogenesis of preeclampsia | Nature Medicine | 2006 | 1,671 |
| 31 | Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance | Nature | 1997 | 1,618 |
| 32 | ISOLATION OF A TUMOR FACTOR RESPONSIBLE FOR ANGIOGENESIS | Journal of Experimental Medicine | 1971 | 1,584 |
| 33 | Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus | Nature Reviews Molecular Cell Biology | 2009 | 1,564 |
| 34 | A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome. | Journal of Bone and Joint Surgery - Series A | 1993 | 1,559 |
| 35 | Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage | Proceedings of the National Academy of Sciences of the United States of America | 1980 | 1,558 |
| 36 | Design and Endpoints of Clinical Trials in Hepatocellular Carcinoma | Journal of the National Cancer Institute | 2008 | 1,554 |
| 37 | Multimodal strategies to improve surgical outcome | American Journal of Surgery | 2002 | 1,538 |
| 38 | EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,495 |
| 39 | Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 1,481 |
| 40 | Isolation of circulating tumor cells using a microvortex-generating herringbone-chip | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 1,473 |
| 41 | Microscale technologies for tissue engineering and biology | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 1,461 |
| 42 | Cellular mechanotransduction: putting all the pieces together again | FASEB Journal | 2006 | 1,448 |
| 43 | TENSEGRITY: THE ARCHITECTURAL BASIS OF CELLULAR MECHANOTRANSDUCTION | Annual Review of Physiology | 1997 | 1,430 |
| 44 | A network-based analysis of systemic inflammation in humans | Nature | 2005 | 1,429 |
| 45 | Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis | Nature | 2003 | 1,402 |
| 46 | Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma | Cell | 2018 | 1,370 |
| 47 | The therapeutic potential of carbon monoxide | Nature Reviews Drug Discovery | 2010 | 1,362 |
| 48 | Comparison of Digital Rectal Examination and Serum Prostate Specific Antigen in the Early Detection of Prostate Cancer: Results of a Multicenter Clinical Trial of 6,630 Men | Journal of Urology | 1994 | 1,354 |
| 49 | Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018 | World Journal of Surgery | 2019 | 1,307 |
| 50 | A single-cell survey of the small intestinal epithelium | Nature | 2017 | 1,303 |
