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Top Articles

#TitleJournalYearCitations
1Cholangiocarcinoma 2020: the next horizon in mechanisms and managementNature Reviews Gastroenterology and Hepatology20201,155
2Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic StressCancer Cell2015596
3Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With CancerJAMA Oncology2019396
4Ongoing Clinical Trials for the Management of the COVID-19 PandemicTrends in Pharmacological Sciences2020311
5German Association of Endocrine Surgeons practice guideline for the surgical management of malignant thyroid tumorsLangenbeck's Archives of Surgery2013226
6A framework for the development of effective anti-metastatic agentsNature Reviews Clinical Oncology2019223
7Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environmentsCancer & Metabolism2016186
8Isoflurane, a Commonly Used Volatile Anesthetic, Enhances Renal Cancer Growth and Malignant Potential via the Hypoxia-inducible Factor Cellular Signaling Pathway In VitroAnesthesiology2013177
9Intragenic DNA methylation: implications of this epigenetic mechanism for cancer researchBritish Journal of Cancer2012168
10German Association of Endocrine Surgeons practice guidelines for the surgical treatment of benign thyroid diseaseLangenbeck's Archives of Surgery2011154
11Mechanisms of endometrial progesterone resistanceMolecular and Cellular Endocrinology2012151
12Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with CancerCancer Discovery2020151
13Distinct Clinical Phenotypes Associated with JAK2V617F Reflect Differential STAT1 SignalingCancer Cell2010150
14MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and ProgressionGastroenterology2014141
15Multimodal management of neuroendocrine liver metastasesHpb2010134
16Non-alcoholic fatty liver disease: A sign of systemic diseaseMetabolism: Clinical and Experimental2017132
17Integrated analysis of concomitant medications and oncological outcomes from PD-1/PD-L1 checkpoint inhibitors in clinical practice2020126
18MicroRNAs Targeting Oncogenes Are Down-Regulated in Pancreatic Malignant Transformation from Benign TumorsPLoS ONE2012122
19Molecular mechanisms of hypoxia in cancerClinical and Translational Imaging2017119
20Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell SubsetsCell Metabolism2018110
21Use of [11C]Choline PET-CT as a Noninvasive Method for Detecting Pelvic Lymph Node Status from Prostate Cancer and Relationship with Choline Kinase ExpressionClinical Cancer Research2011107
22Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serumNature Communications2021107
23A Review of Circulating Tumour Cell Enrichment TechnologiesCancers2021102
24Is There a Link Between Genome-Wide Hypomethylation in Blood and Cancer Risk?Cancer Prevention Research201297
25Programmed death ligand-1 over-expression correlates with malignancy and contributes to immune regulation in ovarian cancerCancer Immunology, Immunotherapy201496
26Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian CancerCancer Research201596
27Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free SurvivalClinical Cancer Research201183
28FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cellsOncogene201783
29Reduced Dissemination of Circulating Tumor Cells With No-Touch Isolation Surgical Technique in Patients With Pancreatic CancerJAMA Surgery201481
30International Association of Pancreatology (IAP)/European Pancreatic Club (EPC) consensus review of guidelines for the treatment of pancreatic cancerPancreatology201681
31Effect of concomitant medications with immune-modulatory properties on the outcomes of patients with advanced cancer treated with immune checkpoint inhibitors: development and validation of a novel prognostic indexEuropean Journal of Cancer202181
32[18F]FLT: An imaging biomarker of tumour proliferation for assessment of tumour response to treatmentEuropean Journal of Cancer201278
33High-Speed Quantitative UPLC-MS Analysis of Multiple Amines in Human Plasma and Serum via Precolumn Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate: Application to Acetaminophen-Induced Liver FailureAnalytical Chemistry201778
34Antibiotic therapy and outcome from immune-checkpoint inhibitors201977
35Immunotoxicity from checkpoint inhibitor therapy: clinical features and underlying mechanismsImmunology202075
36Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient dataGynecologic Oncology201974
37Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry studyLancet Oncology, The202173
38Gain of chromosome band 7q11 in papillary thyroid carcinomas of young patients is associated with exposure to low-dose irradiationProceedings of the National Academy of Sciences of the United States of America201170
39Immunogenicity of the BNT162b2 vaccine in frail or disabled nursing home residents: COVID‐A studyJournal of the American Geriatrics Society202169
40Cellular senescence and aging: the role of B-MYBAging Cell201468
41Growth Arrest-Specific Transcript 5 Associated snoRNA Levels Are Related to p53 Expression and DNA Damage in Colorectal CancerPLoS ONE201466
42Clinical implications of heterogeneity in PD-L1 immunohistochemical detection in hepatocellular carcinoma: the Blueprint-HCC studyBritish Journal of Cancer201966
43Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cellsOncogene201662
44Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T CellsMolecular Therapy201761
45Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancerEJNMMI Research201560
46Analysis of polar urinary metabolites for metabolic phenotyping using supercritical fluid chromatography and mass spectrometryJournal of Chromatography A201660
47Programmed cell death ligands expression in phaeochromocytomas and paragangliomas: Relationship with the hypoxic response, immune evasion and malignant behaviorOncoImmunology201760
48S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI ImagingJournal of Molecular Medicine201256
49The systemic inflammatory response as a source of biomarkers and therapeutic targets in hepatocellular carcinomaLiver International201956
50Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian CancerClinical Cancer Research201355