| # | Title | Journal | Year | Citations |
|---|
| 1 | The immunology of hepatocellular carcinoma | Nature Immunology | 2018 | 697 |
| 2 | Localization of Pancreatic Endocrine Tumors by Endoscopic Ultrasonography | New England Journal of Medicine | 1992 | 690 |
| 3 | Acupuncture for Patients With Migraine | JAMA - Journal of the American Medical Association | 2005 | 556 |
| 4 | Staging of pancreatic and ampullary carcinoma by endoscopic ultrasonography | Gastroenterology | 1992 | 534 |
| 5 | The C-Terminal Regulatory Domain Is the RNA 5′-Triphosphate Sensor of RIG-I | Molecular Cell | 2008 | 458 |
| 6 | The impact of patient expectations on outcomes in four randomized controlled trials of acupuncture in patients with chronic pain | Pain | 2007 | 454 |
| 7 | Chemotherapy in advanced biliary tract carcinoma: a pooled analysis of clinical trials | British Journal of Cancer | 2007 | 436 |
| 8 | Endoscopic ultrasound in pancreatic tumor diagnosis | Gastrointestinal Endoscopy | 1991 | 424 |
| 9 | Oncogenic KRAS signalling in pancreatic cancer | British Journal of Cancer | 2014 | 423 |
| 10 | Transluminal endoscopic necrosectomy after acute pancreatitis: a multicentre study with long-term follow-up (the GEPARD Study) | Gut | 2009 | 421 |
| 11 | Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b | Oncogene | 2000 | 348 |
| 12 | Acupuncture in patients with tension-type headache: randomised controlled trial | BMJ: British Medical Journal | 2005 | 347 |
| 13 | Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling | Cancer Cell | 2017 | 332 |
| 14 | The Munich Polypectomy Study (MUPS): Prospective Analysis of Complications and Risk Factors in 4000 Colonic Snare Polypectomies | Endoscopy | 2005 | 319 |
| 15 | ERCP or EUS for tissue diagnosis of biliary strictures? a prospective comparative study | Gastrointestinal Endoscopy | 2004 | 301 |
| 16 | A prospective comparison of the diagnostic accuracy of ERCP, MRCP, CT, and EUS in biliary strictures | Gastrointestinal Endoscopy | 2002 | 285 |
| 17 | Acupuncture for migraine prophylaxis | Gastrointestinal Endoscopy | 2009 | 272 |
| 18 | Endosonographic Staging of Esophageal Cancer: A Review of Literature Results | Gastrointestinal Endoscopy Clinics of North America | 1995 | 259 |
| 19 | St John's wort for major depression | The Cochrane Library | 2008 | 240 |
| 20 | Lactose drives Enterococcus expansion to promote graft-versus-host disease | Science | 2019 | 217 |
| 21 | Impact of Study Quality on Outcome in Placebo-Controlled Trials of Homeopathy | Journal of Clinical Epidemiology | 1999 | 198 |
| 22 | St John's wort for depression | British Journal of Psychiatry | 2005 | 196 |
| 23 | Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis | Cell Stem Cell | 2016 | 196 |
| 24 | Acupuncture for tension-type headache | Cell Stem Cell | 2009 | 190 |
| 25 | A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer | Nature Medicine | 2014 | 188 |
| 26 | Local staging and assessment of resectability in carcinoma of the esophagus, stomach, and duodenum by endoscopic ultrasonography | Gastrointestinal Endoscopy | 1992 | 187 |
| 27 | Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks Commentary: Has hypericum found its place in antidepressant treatment? | BMJ: British Medical Journal | 1999 | 183 |
| 28 | New Techniques Accuracy of Endoscopic Ultrasonography in Upper Gastrointestinal Submucosal Lesions: a Prospective Multicenter Study | Scandinavian Journal of Gastroenterology | 2002 | 182 |
| 29 | Postprandial Response of Plasma Ghrelin Levels to Various Test Meals in Relation to Food Intake, Plasma Insulin, and Glucose | Journal of Clinical Endocrinology and Metabolism | 2004 | 181 |
| 30 | Differential effect of protein and fat on plasma ghrelin levels in man | Regulatory Peptides | 2003 | 160 |
| 31 | Treatment of Achalasia: Botulinum Toxin Injection vs. Pneumatic Balloon Dilation. A Prospective Study with Long-Term Follow-Up | Endoscopy | 2001 | 147 |
| 32 | COVID-19 in cancer patients: clinical characteristics and outcome—an analysis of the LEOSS registry | Annals of Hematology | 2021 | 127 |
| 33 | Crosstalk between Keratinocytes and Adaptive Immune Cells in an IκBα Protein-Mediated Inflammatory Disease of the Skin | Immunity | 2007 | 124 |
| 34 | Multislice computed tomography versus contrast-enhanced ultrasound in evaluation of complex cystic renal masses using the Bosniak classification system | Clinical Hemorheology and Microcirculation | 2008 | 120 |
| 35 | Endoscopic transpapillary brush cytology and forceps biopsy in patients with hilar cholangiocarcinoma | World Journal of Gastroenterology | 2008 | 120 |
| 36 | Randomized Controlled Trials of Individualized Homeopathy: A State-of-the-Art Review | Journal of Alternative and Complementary Medicine | 1998 | 116 |
| 37 | Requirement of toll‐like receptor 7 for pristane‐induced production of autoantibodies and development of murine lupus nephritis | Arthritis and Rheumatism | 2008 | 116 |
| 38 | Biopsy surveillance is still necessary in patients with Barrett's oesophagus despite new endoscopic imaging techniques | Gut | 2003 | 115 |
| 39 | Drug-induced dysphagia | Dysphagia | 1993 | 109 |
| 40 | Endosonographic Diagnosis of Submucosal Upper Gastrointestinal Tract Tumors | Scandinavian Journal of Gastroenterology | 1992 | 107 |
| 41 | You get what you expect? A critical appraisal of imaging methodology in endosonographic cancer staging | Gut | 2002 | 105 |
| 42 | Single-nucleotide promoter polymorphism alters transcription of neuronal nitric oxide synthase exon 1c in infantile hypertrophic pyloric stenosis | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 101 |
| 43 | A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer | Cell | 2015 | 100 |
| 44 | Distinct expression of splice variants of neuronal nitric oxide synthase in the human gastrointestinal tract | Gastroenterology | 2000 | 99 |
| 45 | Differential Association of Basal and Postprandial Plasma Ghrelin With Leptin, Insulin, and Type 2 Diabetes | Diabetes | 2005 | 99 |
| 46 | Activation of the coagulation cascade in severe falciparum malaria through the intrinsic pathway | British Journal of Haematology | 1994 | 98 |
| 47 | Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship | European Journal of Clinical Microbiology and Infectious Diseases | 2021 | 98 |
| 48 | Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach | Regulatory Peptides | 2004 | 92 |
| 49 | Percutaneous cholangioscopic or transpapillary insertion of self-expanding biliary metal stents | Gastrointestinal Endoscopy | 1991 | 91 |
| 50 | Adverse Effects of St. John’s Wort | Journal of Clinical Psychiatry | 2004 | 91 |
