| # | Title | Journal | Year | Citations |
|---|
| 1 | Development of a shuttle walking test of disability in patients with chronic airways obstruction. | Thorax | 1992 | 1,152 |
| 2 | Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ) | Thorax | 2003 | 752 |
| 3 | Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial | Lancet, The | 2000 | 514 |
| 4 | Eosinophilic Bronchitis Is an Important Cause of Chronic Cough | American Journal of Respiratory and Critical Care Medicine | 1999 | 406 |
| 5 | The endurance shuttle walk: a new field test for the assessment of endurance capacity in chronic obstructive pulmonary disease | Thorax | 1999 | 365 |
| 6 | The relationship between clinical outcomes and medication adherence in difficult-to-control asthma: Table 1 | Thorax | 2012 | 259 |
| 7 | An early rehabilitation intervention to enhance recovery during hospital admission for an exacerbation of chronic respiratory disease: randomised controlled trial | BMJ, The | 2014 | 235 |
| 8 | Noneosinophilic asthma: A distinct clinical and pathologic phenotype | Journal of Allergy and Clinical Immunology | 2007 | 230 |
| 9 | Development of a self-reported Chronic Respiratory Questionnaire (CRQ-SR) | Thorax | 2001 | 222 |
| 10 | A randomized, double‐blind, placebo‐controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma | Clinical and Experimental Allergy | 2012 | 185 |
| 11 | Induced Sputum Inflammatory Mediator Concentrations in Chronic Cough | American Journal of Respiratory and Critical Care Medicine | 2004 | 173 |
| 12 | Airway inflammation, airway responsiveness and cough before and after inhaled budesonide in patients with eosinophilic bronchitis | European Respiratory Journal | 2000 | 160 |
| 13 | Nutritional enhancement of exercise performance in chronic obstructive pulmonary disease: a randomised controlled trial | Thorax | 2003 | 160 |
| 14 | Current evidence and future research needs for FeNO measurement in respiratory diseases | Respiratory Medicine | 2014 | 157 |
| 15 | Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer | Clinical Cancer Research | 2000 | 145 |
| 16 | Eosinophil adhesion to nasal polyp endothelium is P-selectin-dependent. | Journal of Experimental Medicine | 1994 | 142 |
| 17 | Cough frequency, cough sensitivity and health status in patients with chronic cough | Respiratory Medicine | 2006 | 141 |
| 18 | Trends in incidence of small cell lung cancer and all lung cancer | Lung Cancer | 2012 | 131 |
| 19 | Activation of human mast cells through the platelet-activating factor receptor | Journal of Allergy and Clinical Immunology | 2010 | 129 |
| 20 | A randomised controlled trial of four weeks versus seven weeks of pulmonary rehabilitation in chronic obstructive pulmonary disease | Thorax | 2001 | 124 |
| 21 | Cough and Glottic-Stop Reflex Sensitivity in Health and Disease | Chest | 2005 | 121 |
| 22 | Human mast cell cytokines | Clinical and Experimental Allergy | 1996 | 120 |
| 23 | Immunopathology and human mast cell cytokines | Critical Reviews in Oncology/Hematology | 1999 | 117 |
| 24 | An evaluation of the impact of large-scale interventions to raise public awareness of a lung cancer symptom | British Journal of Cancer | 2015 | 115 |
| 25 | A short outpatient pulmonary rehabilitation programme: immediate and longer term effects on exercise performance and quality of life | Respiratory Medicine | 1998 | 114 |
| 26 | Chemokines and their receptors as potential targets for the treatment of asthma | British Journal of Pharmacology | 2007 | 109 |
| 27 | EAACI position statement on asthma exacerbations and severe asthma | Allergy: European Journal of Allergy and Clinical Immunology | 2013 | 107 |
| 28 | Eosinophils in the 1990s: New perspectives on their role in health and disease | Postgraduate Medical Journal | 1994 | 104 |
| 29 | Human mast cells express stem cell factor | Postgraduate Medical Journal | 1998 | 104 |
| 30 | Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis | Thorax | 2003 | 100 |
| 31 | New insights into the relationship between airway inflammation and asthma | Clinical Science | 2002 | 97 |
| 32 | “We are not worthy” – understanding why patients decline pulmonary rehabilitation following an acute exacerbation of COPD | Disability and Rehabilitation | 2015 | 96 |
| 33 | A novel formulation of inhaled sodium cromoglicate (PA101) in idiopathic pulmonary fibrosis and chronic cough: a randomised, double-blind, proof-of-concept, phase 2 trial | Lancet Respiratory Medicine,the | 2017 | 95 |
| 34 | Interactive web-based pulmonary rehabilitation programme: a randomised controlled feasibility trial | BMJ Open | 2017 | 93 |
| 35 | Induced sputum and other outcome measures in chronic obstructive pulmonary disease: safety and repeatability | Respiratory Medicine | 2001 | 92 |
| 36 | Bedside Assessment of Quadriceps Muscle by Ultrasound after Admission for Acute Exacerbations of Chronic Respiratory Disease | American Journal of Respiratory and Critical Care Medicine | 2015 | 92 |
| 37 | Isolation of filamentous fungi from sputum in asthma is associated with reduced post‐bronchodilator FEV1 | Clinical and Experimental Allergy | 2012 | 90 |
| 38 | Ligation of CD69 induces apoptosis and cell death in human eosinophils cultured with granulocyte-macrophage colony-stimulating factor | Blood | 1996 | 88 |
| 39 | National comparisons of lung cancer survival in England, Norway and Sweden 2001-2004: differences occur early in follow-up | Thorax | 2010 | 88 |
| 40 | The reclassification of asthma based on subphenotypes | Current Opinion in Allergy and Clinical Immunology | 2007 | 85 |
| 41 | Functional and structural characterization of the eosinophil P-selectin ligand. | Journal of Immunology | 1996 | 83 |
| 42 | A comparison of three disease-specific and two generic health-status measures to evaluate the outcome of pulmonary rehabilitation in COPD | Respiratory Medicine | 2001 | 80 |
| 43 | Knowledge of lung cancer symptoms and risk factors in the UK: development of a measure and results from a population-based survey | Thorax | 2012 | 80 |
| 44 | Integrin α 4 β 7 mediates human eosinophil interaction with MAdCAM‐1, VCAM‐1 and fibronectin | Immunology | 1996 | 79 |
| 45 | The beneficial effects of specialist thoracic surgery on the resection rate for non-small-cell lung cancer | Lung Cancer | 2004 | 75 |
| 46 | An Automated System for 24-h Monitoring of Cough Frequency: The Leicester Cough Monitor | IEEE Transactions on Biomedical Engineering | 2007 | 75 |
| 47 | Ultrasound assessment of lower limb muscle mass in response to resistance training in COPD | Respiratory Research | 2012 | 74 |
| 48 | Effectiveness of voriconazole in the treatment of Aspergillus fumigatus–associated asthma (EVITA3 study) | Journal of Allergy and Clinical Immunology | 2014 | 74 |
| 49 | Functional and structural characterization of the eosinophil P-selectin ligand | Journal of Immunology | 1996 | 74 |
| 50 | Domains, constructs and the development of the breathing problems questionnaire | Quality of Life Research | 1994 | 73 |
