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Top Articles

#TitleJournalYearCitations
1The golden age: gold nanoparticles for biomedicineChemical Society Reviews20122,900
2Common activation mechanism of class A GPCRsELife2019339
3COVID-19-Related StrokeTranslational Stroke Research2020315
4The critical role of Akt in cardiovascular functionVascular Pharmacology2015299
5Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cellsJournal of Biological Chemistry2018254
6Arginase: an old enzyme with new tricksTrends in Pharmacological Sciences2015236
7Neurotoxicity in acute and repeated organophosphate exposureToxicology2018197
8Functional consequences of repeated organophosphate exposure: Potential non-cholinergic mechanisms2012195
9Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage ProductionMolecular Therapy2016165
10Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimersNature Chemical Biology2011135
11Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathwayBritish Journal of Pharmacology2012133
12Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathwayAmerican Journal of Physiology - Cell Physiology2011118
13Variable G protein determinants of GPCR coupling selectivityProceedings of the National Academy of Sciences of the United States of America2019111
14CODA-RET reveals functional selectivity as a result of GPCR heteromerizationNature Chemical Biology2011107
15Long noncoding RNA NEAT1 (nuclear paraspeckle assembly transcript 1) is critical for phenotypic switching of vascular smooth muscle cellsProceedings of the National Academy of Sciences of the United States of America2018107
16Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in MiceAntioxidants and Redox Signaling2011106
17Deletion of Yes-Associated Protein (YAP) Specifically in Cardiac and Vascular Smooth Muscle Cells Reveals a Crucial Role for YAP in Mouse Cardiovascular DevelopmentCirculation Research2014106
18Increased Superoxide and Endothelial NO Synthase Uncoupling in Blood Vessels of Bmal1-Knockout MiceCirculation Research2012103
19Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of diseaseJournal of Clinical Investigation201194
20Positive allosteric modulator of alpha 7 nicotinic-acetylcholine receptors, PNU-120596 augments the effects of donepezil on learning and memory in aged rodents and non-human primatesNeuropharmacology201390
21Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen speciesFree Radical Biology and Medicine201487
22Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signalingNature Communications202085
23Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1Cardiovascular Research201782
24Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockoutCardiovascular Research201381
25Exposure to variable prenatal stress in rats: Effects on anxiety-related behaviors, innate and contextual fear, and fear extinctionBehavioural Brain Research201380
26YAP Is a Critical Inducer of SOCS3, Preventing Reactive AstrogliosisCerebral Cortex201679
27Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscleAmerican Journal of Physiology - Endocrinology and Metabolism201178
28The Bile Acid Receptor TGR5 Does Not Interact with β-Arrestins or Traffic to Endosomes but Transmits Sustained Signals from Plasma Membrane RaftsJournal of Biological Chemistry201378
29RAB26-dependent autophagy protects adherens junctional integrity in acute lung injuryAutophagy201878
30Diabetes-induced vascular dysfunction involves arginase IAmerican Journal of Physiology - Heart and Circulatory Physiology201277
31Toxicity and Cellular Uptake of Gold Nanorods in Vascular Endothelium and Smooth Muscles of Isolated Rat Blood Vessel: Importance of Surface ModificationSmall201276
32Regulation of NADPH Oxidase 5 by Protein Kinase C IsoformsPLoS ONE201475
33CrossTalk opposing view: Weighing the evidence for class A GPCR dimers, the jury is still outJournal of Physiology201474
34Sensitive and High Resolution Localization and Tracking of Membrane Proteins in Live Cells with BRETTraffic201272
35Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosisProceedings of the National Academy of Sciences of the United States of America201170
36Epigenetic Landscape of Parkinson's Disease: Emerging Role in Disease Mechanisms and Therapeutic ModalitiesNeurotherapeutics201369
37Role of C/EBP homologous protein and endoplasmic reticulum stress in asthma exacerbation by regulating the IL-4/signal transducer and activator of transcription 6/transcription factor EC/IL-4 receptor α positive feedback loop in M2 macrophagesJournal of Allergy and Clinical Immunology201769
38Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammationNature Communications201769
39Oxidative stress contributes to sex differences in angiotensin II-mediated hypertension in spontaneously hypertensive ratsAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology201264
40The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetesDiabetologia201363
41Distinct Actions of Endothelin A-Selective Versus Combined Endothelin A/B Receptor Antagonists in Early Diabetic Kidney DiseaseJournal of Pharmacology and Experimental Therapeutics201162
42Protein Kinase C-α and Arginase I Mediate Pneumolysin-Induced Pulmonary Endothelial HyperpermeabilityAmerican Journal of Respiratory Cell and Molecular Biology201260
43Small GTPase regulation of GPCR anterograde traffickingTrends in Pharmacological Sciences201259
44Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolismCell Death and Disease201459
45GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2Gastroenterology201959
46α7 nicotinic acetylcholine receptors as therapeutic targets in schizophrenia: Update on animal and clinical studies and strategies for the futureNeuropharmacology202059
47Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOSAmerican Journal of Physiology - Heart and Circulatory Physiology201358
48Muscle Yap Is a Regulator of Neuromuscular Junction Formation and RegenerationJournal of Neuroscience201758
49miR-18a-5p Inhibits Sub-pleural Pulmonary Fibrosis by Targeting TGF-β Receptor IIMolecular Therapy201757
50Neddylation mediates ventricular chamber maturation through repression of Hippo signalingProceedings of the National Academy of Sciences of the United States of America201857