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Department of Pharmacology and Toxicology
›
top-articles
Department of Pharmacology and Toxicology
301
(top 1%)
papers
12.2K
(top 1%)
citations
51
(top 1%)
h
-index
98
(top 1%)
g
-index
328
all documents
13.3K
doc citations
2.5K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
The golden age: gold nanoparticles for biomedicine
Chemical Society Reviews
2012
2,900
2
Common activation mechanism of class A GPCRs
ELife
2019
339
3
COVID-19-Related Stroke
Translational Stroke Research
2020
315
4
The critical role of Akt in cardiovascular function
Vascular Pharmacology
2015
299
5
Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells
Journal of Biological Chemistry
2018
254
6
Arginase: an old enzyme with new tricks
Trends in Pharmacological Sciences
2015
236
7
Neurotoxicity in acute and repeated organophosphate exposure
Toxicology
2018
197
8
Functional consequences of repeated organophosphate exposure: Potential non-cholinergic mechanisms
2012
195
9
Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage Production
Molecular Therapy
2016
165
10
Inactive-state preassembly of Gq-coupled receptors and Gq heterotrimers
Nature Chemical Biology
2011
135
11
Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway
British Journal of Pharmacology
2012
133
12
Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway
American Journal of Physiology - Cell Physiology
2011
118
13
Variable G protein determinants of GPCR coupling selectivity
Proceedings of the National Academy of Sciences of the United States of America
2019
111
14
CODA-RET reveals functional selectivity as a result of GPCR heteromerization
Nature Chemical Biology
2011
107
15
Long noncoding RNA
NEAT1
(nuclear paraspeckle assembly transcript 1) is critical for phenotypic switching of vascular smooth muscle cells
Proceedings of the National Academy of Sciences of the United States of America
2018
107
16
Hydrogen Sulfide Ameliorates Tobacco Smoke-Induced Oxidative Stress and Emphysema in Mice
Antioxidants and Redox Signaling
2011
106
17
Deletion of Yes-Associated Protein (YAP) Specifically in Cardiac and Vascular Smooth Muscle Cells Reveals a Crucial Role for YAP in Mouse Cardiovascular Development
Circulation Research
2014
106
18
Increased Superoxide and Endothelial NO Synthase Uncoupling in Blood Vessels of Bmal1-Knockout Mice
Circulation Research
2012
103
19
Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease
Journal of Clinical Investigation
2011
94
20
Positive allosteric modulator of alpha 7 nicotinic-acetylcholine receptors, PNU-120596 augments the effects of donepezil on learning and memory in aged rodents and non-human primates
Neuropharmacology
2013
90
21
Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species
Free Radical Biology and Medicine
2014
87
22
Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling
Nature Communications
2020
85
23
Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1
Cardiovascular Research
2017
82
24
Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout
Cardiovascular Research
2013
81
25
Exposure to variable prenatal stress in rats: Effects on anxiety-related behaviors, innate and contextual fear, and fear extinction
Behavioural Brain Research
2013
80
26
YAP Is a Critical Inducer of SOCS3, Preventing Reactive Astrogliosis
Cerebral Cortex
2016
79
27
Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle
American Journal of Physiology - Endocrinology and Metabolism
2011
78
28
The Bile Acid Receptor TGR5 Does Not Interact with β-Arrestins or Traffic to Endosomes but Transmits Sustained Signals from Plasma Membrane Rafts
Journal of Biological Chemistry
2013
78
29
RAB26-dependent autophagy protects adherens junctional integrity in acute lung injury
Autophagy
2018
78
30
Diabetes-induced vascular dysfunction involves arginase I
American Journal of Physiology - Heart and Circulatory Physiology
2012
77
31
Toxicity and Cellular Uptake of Gold Nanorods in Vascular Endothelium and Smooth Muscles of Isolated Rat Blood Vessel: Importance of Surface Modification
Small
2012
76
32
Regulation of NADPH Oxidase 5 by Protein Kinase C Isoforms
PLoS ONE
2014
75
33
CrossTalk opposing view: Weighing the evidence for class A GPCR dimers, the jury is still out
Journal of Physiology
2014
74
34
Sensitive and High Resolution Localization and Tracking of Membrane Proteins in Live Cells with
BRET
Traffic
2012
72
35
Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis
Proceedings of the National Academy of Sciences of the United States of America
2011
70
36
Epigenetic Landscape of Parkinson's Disease: Emerging Role in Disease Mechanisms and Therapeutic Modalities
Neurotherapeutics
2013
69
37
Role of C/EBP homologous protein and endoplasmic reticulum stress in asthma exacerbation by regulating the IL-4/signal transducer and activator of transcription 6/transcription factor EC/IL-4 receptor α positive feedback loop in M2 macrophages
Journal of Allergy and Clinical Immunology
2017
69
38
Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation
Nature Communications
2017
69
39
Oxidative stress contributes to sex differences in angiotensin II-mediated hypertension in spontaneously hypertensive rats
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
2012
64
40
The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes
Diabetologia
2013
63
41
Distinct Actions of Endothelin A-Selective Versus Combined Endothelin A/B Receptor Antagonists in Early Diabetic Kidney Disease
Journal of Pharmacology and Experimental Therapeutics
2011
62
42
Protein Kinase C-α and Arginase I Mediate Pneumolysin-Induced Pulmonary Endothelial Hyperpermeability
American Journal of Respiratory Cell and Molecular Biology
2012
60
43
Small GTPase regulation of GPCR anterograde trafficking
Trends in Pharmacological Sciences
2012
59
44
Arginase 2 deficiency reduces hyperoxia-mediated retinal neurodegeneration through the regulation of polyamine metabolism
Cell Death and Disease
2014
59
45
GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2
Gastroenterology
2019
59
46
α7 nicotinic acetylcholine receptors as therapeutic targets in schizophrenia: Update on animal and clinical studies and strategies for the future
Neuropharmacology
2020
59
47
Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOS
American Journal of Physiology - Heart and Circulatory Physiology
2013
58
48
Muscle Yap Is a Regulator of Neuromuscular Junction Formation and Regeneration
Journal of Neuroscience
2017
58
49
miR-18a-5p Inhibits Sub-pleural Pulmonary Fibrosis by Targeting TGF-β Receptor II
Molecular Therapy
2017
57
50
Neddylation mediates ventricular chamber maturation through repression of Hippo signaling
Proceedings of the National Academy of Sciences of the United States of America
2018
57
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