| # | Title | Journal | Year | Citations |
|---|
| 1 | The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After | Surgery | 2017 | 2,655 |
| 2 | Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages | PLoS Medicine | 2010 | 1,300 |
| 3 | Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA | Science | 2014 | 774 |
| 4 | PET to assess early metabolic response and to guide treatment of adenocarcinoma of the oesophagogastric junction: the MUNICON phase II trial | Lancet Oncology, The | 2007 | 757 |
| 5 | Borderline resectable pancreatic cancer: A consensus statement by the International Study Group of Pancreatic Surgery (ISGPS) | Surgery | 2014 | 736 |
| 6 | Animal Models of sepsis: setting the stage | Nature Reviews Drug Discovery | 2005 | 673 |
| 7 | Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy | Cancer | 2003 | 607 |
| 8 | Systematic Review and Meta-Analysis of the Role of Defunctioning Stoma in Low Rectal Cancer Surgery | Annals of Surgery | 2008 | 512 |
| 9 | Definition of a standard lymphadenectomy in surgery for pancreatic ductal adenocarcinoma: A consensus statement by the International Study Group on Pancreatic Surgery (ISGPS) | Surgery | 2014 | 506 |
| 10 | Metabolic Imaging Predicts Response, Survival, and Recurrence in Adenocarcinomas of the Esophagogastric Junction | Journal of Clinical Oncology | 2006 | 458 |
| 11 | Early Esophageal Cancer | Annals of Surgery | 2005 | 399 |
| 12 | Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma | Nature Medicine | 2015 | 349 |
| 13 | Cachexia Worsens Prognosis in Patients with Resectable Pancreatic Cancer | Journal of Gastrointestinal Surgery | 2008 | 341 |
| 14 | Pancreatic Neuropathy and Neuropathic Pain—A Comprehensive Pathomorphological Study of 546 Cases | Gastroenterology | 2009 | 309 |
| 15 | Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer | Cancer Cell | 2013 | 291 |
| 16 | FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings | European Journal of Nuclear Medicine and Molecular Imaging | 2003 | 290 |
| 17 | Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 285 |
| 18 | Surgical data science for next-generation interventions | Nature Biomedical Engineering | 2017 | 283 |
| 19 | Ratio of invaded to removed lymph nodes as a predictor of survival in squamous cell carcinoma of the oesophagus | British Journal of Surgery | 2005 | 272 |
| 20 | Diffuse Type Gastric and Lobular Breast Carcinoma in a Familial Gastric Cancer Patient with an E-Cadherin Germline Mutation | American Journal of Pathology | 1999 | 267 |
| 21 | Are Squamous and Adenocarcinomas of the Esophagus the Same Disease? | Seminars in Radiation Oncology | 2007 | 265 |
| 22 | CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 255 |
| 23 | Comparison between breast volume measurement using 3D surface imaging and classical techniques | Breast | 2007 | 244 |
| 24 | Extended pancreatectomy in pancreatic ductal adenocarcinoma: Definition and consensus of the International Study Group for Pancreatic Surgery (ISGPS) | Surgery | 2014 | 226 |
| 25 | Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial | Lancet, The | 2017 | 221 |
| 26 | Prognostic factors of resected adenocarcinoma of the esophagus | Surgery | 1995 | 219 |
| 27 | Mucinous and Signet-Ring Cell Colorectal Cancers Differ from Classical Adenocarcinomas in Tumor Biology and Prognosis | Annals of Surgery | 2013 | 216 |
| 28 | Definition and classification of chyle leak after pancreatic operation: A consensus statement by the International Study Group on Pancreatic Surgery | Surgery | 2017 | 216 |
| 29 | Guidelines for the understanding and management of pain in chronic pancreatitis | Pancreatology | 2017 | 214 |
| 30 | Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer | Molecular Cancer | 2015 | 210 |
| 31 | Statistical modeling and recognition of surgical workflow | Medical Image Analysis | 2012 | 203 |
| 32 | High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue | Nature Protocols | 2016 | 190 |
| 33 | Gut microbiota modulate T cell trafficking into human colorectal cancer | Gut | 2018 | 189 |
| 34 | Micrometastasis and tumor cell microinvolvement of lymph nodes from esophageal squamous cell carcinoma | Cancer | 1998 | 179 |
| 35 | Pancreatic anastomosis after pancreatoduodenectomy: A position statement by the International Study Group of Pancreatic Surgery (ISGPS) | Surgery | 2017 | 177 |
| 36 | Prognosis of early esophageal cancer. Comparison between adeno-and squamous cell carcinoma | Cancer | 1995 | 175 |
| 37 | Failure of antireflux surgery: causes and management strategies | American Journal of Surgery | 1996 | 170 |
| 38 | Inhibition of CD47 Effectively Targets Pancreatic Cancer Stem Cells via Dual Mechanisms | Clinical Cancer Research | 2015 | 170 |
| 39 | Temporal Trends in Long-Term Survival and Cure Rates in Esophageal Cancer: A SEER Database Analysis | Journal of Thoracic Oncology | 2012 | 168 |
| 40 | Effect of Preoperative Radio(chemo)therapy on Long-term Functional Outcome in Rectal Cancer Patients: A Systematic Review and Meta-analysis | Annals of Surgical Oncology | 2013 | 168 |
| 41 | Meta-analysis of neoadjuvant treatment modalities and definitive non-surgical therapy for oesophageal squamous cell cancer | British Journal of Surgery | 2011 | 166 |
| 42 | Heterotopic Gastric Mucosa of the Esophagus: Literature-Review and Proposal of a Clinicopathologic Classification | American Journal of Gastroenterology | 2004 | 164 |
| 43 | Role of Endoscopic Ultrasonography in Esophageal Carcinoma | Endoscopy | 1993 | 162 |
| 44 | Efficacy of Annual Colonoscopic Surveillance in Individuals With Hereditary Nonpolyposis Colorectal Cancer | Clinical Gastroenterology and Hepatology | 2010 | 160 |
| 45 | Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes | PLoS Computational Biology | 2012 | 159 |
| 46 | Langerin neg conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 158 |
| 47 | Neural plasticity in pancreatitis and pancreatic cancer | Nature Reviews Gastroenterology and Hepatology | 2015 | 158 |
| 48 | Microenvironmental Determinants of Pancreatic Cancer | Physiological Reviews | 2020 | 156 |
| 49 | Typical and Atypical Carcinoid Tumors of the Lung Are Characterized by 11q Deletions as Detected by Comparative Genomic Hybridization | American Journal of Pathology | 1998 | 151 |
| 50 | Question Sets and Answers | American Journal of Pathology | 2015 | 149 |
