| # | Title | Journal | Year | Citations |
|---|
| 1 | Laparoscopic versus conventional appendectomy - a meta-analysis of randomized controlled trials | BMC Gastroenterology | 2010 | 275 |
| 2 | Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation | Nature Genetics | 2016 | 237 |
| 3 | microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis | Oncogene | 2013 | 194 |
| 4 | Guidelines for the diagnosis and treatment of nonalcoholic fatty liver diseases* | Journal of Digestive Diseases | 2008 | 181 |
| 5 | Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations | Nature Genetics | 2012 | 164 |
| 6 | Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer | Gut | 2015 | 163 |
| 7 | VSL#3 probiotics exerts the anti-inflammatory activity via PI3k/Akt and NF-κB pathway in rat model of DSS-induced colitis | Molecular and Cellular Biochemistry | 2013 | 132 |
| 8 | Association between polymorphisms in interleukin‐17A and interleukin‐17F genes and risks of gastric cancer | International Journal of Cancer | 2010 | 120 |
| 9 | The clinical overlap between functional dyspepsia and irritable bowel syndrome based on Rome III criteria | BMC Gastroenterology | 2008 | 119 |
| 10 | Remission induction and maintenance effect of probiotics on ulcerative colitis: A meta-analysis | World Journal of Gastroenterology | 2010 | 107 |
| 11 | VSL#3 probiotics regulate the intestinal epithelial barrier in�vivo and in vitro via the p38 and ERK signaling pathways | International Journal of Molecular Medicine | 2011 | 100 |
| 12 | Prevalence, risk factors and impact of gastroesophageal reflux disease symptoms: A population-based study in South China | Scandinavian Journal of Gastroenterology | 2005 | 92 |
| 13 | A nanoparticulate dual scavenger for targeted therapy of inflammatory bowel disease | Science Advances | 2022 | 87 |
| 14 | Third Chinese National Consensus Report on the management of Helicobacter pylori infection1
(August 2007, Lushan, Jiangxi Province, China) | Journal of Digestive Diseases | 2008 | 75 |
| 15 | Prevalence of Helicobacter pylori Infection and its Relation with Body Mass Index in a Chinese Population | Helicobacter | 2014 | 71 |
| 16 | The Chinese Society of Hepatology position statement on the redefinition of fatty liver disease | Journal of Hepatology | 2021 | 70 |
| 17 | Peroxisome proliferator activated receptor alpha inhibits hepatocarcinogenesis through mediating NF-κB signaling pathway | Oncotarget | 2014 | 70 |
| 18 | Epigenetic inactivation ofBCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival | Gut | 2012 | 69 |
| 19 | Preparation and characterization of solid lipid nanoparticles loaded traditional chinese medicine | International Journal of Biological Macromolecules | 2006 | 59 |
| 20 | Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine | Oncology Reports | 2013 | 59 |
| 21 | Immunohistochemical detection of pepsin in laryngeal mucosa for diagnosing laryngopharyngeal reflux | Laryngoscope | 2011 | 54 |
| 22 | Antinociceptive effect of VSL#3 on visceral hypersensitivity in a rat model of irritable bowel syndrome: a possible action through nitric oxide pathway and enhance barrier function | Molecular and Cellular Biochemistry | 2012 | 52 |
| 23 | The Prevalence of Gastrointestinal Symptoms, Abnormal Liver Function, Digestive System Disease and Liver Disease in COVID-19 Infection | Journal of Clinical Gastroenterology | 2021 | 50 |
| 24 | Sublethal heat treatment of hepatocellular carcinoma promotes intrahepatic metastasis and stemness in a VEGFR1-dependent manner | Cancer Letters | 2019 | 48 |
| 25 | Helicobacter pylori infection promotes Aquaporin 3 expression via the ROS–HIF-1α–AQP3–ROS loop in stomach mucosa: a potential novel mechanism for cancer pathogenesis | Oncogene | 2018 | 47 |
| 26 | An Alternative to Current Therapies of Functional Dyspepsia: Self-Administrated Transcutaneous Electroacupuncture Improves Dyspeptic Symptoms | Evidence-based Complementary and Alternative Medicine | 2014 | 44 |
| 27 | Identification of genes associated with cancer progression and prognosis in lung adenocarcinoma: Analyses based on microarray from Oncomine and The Cancer Genome Atlas databases | Molecular Genetics & Genomic Medicine | 2019 | 42 |
| 28 | Cancer-associated fibroblasts-derived VCAM1 induced by H. pylori infection facilitates tumor invasion in gastric cancer | Oncogene | 2020 | 40 |
| 29 | Recurrence and surveillance of colorectal adenoma after polypectomy in a southern Chinese population | Journal of Gastroenterology | 2010 | 38 |
| 30 | Mucosal Healing Did Not Predict Sustained Clinical Remission in Patients with IBD after Discontinuation of One-Year Infliximab Therapy | PLoS ONE | 2014 | 38 |
| 31 | CircRNAs and its relationship with gastric cancer | Journal of Cancer | 2019 | 38 |
| 32 | Normal Values of 24-Hour Combined Esophageal Multichannel Intraluminal Impedance and pH Monitoring in the Chinese Population | Digestion | 2009 | 36 |
| 33 | Impact of preprocedure simethicone on adenoma detection rate during colonoscopy: a multicenter, endoscopist-blinded randomized controlled trial | Endoscopy | 2018 | 36 |
| 34 | Expression of autotaxin mRNA in human hepatocellular carcinoma | Chinese Medical Journal | 1999 | 36 |
| 35 | Zinc finger E‐box binding factor 1 plays a central role in regulating Epstein‐Barr virus (EBV) latent‐lytic switch and acts as a therapeutic target in EBV‐associated gastric cancer | Cancer | 2012 | 33 |
| 36 | Altered integrity and decreased expression of hepatocyte tight junctions in rifampicin-induced cholestasis in mice | Toxicology and Applied Pharmacology | 2009 | 32 |
| 37 | Hypoxanthine guanine phosphoribosyltransferase activity is related to 6-thioguanine nucleotide concentrations and thiopurine-induced leukopenia in the treatment of inflammatory bowel disease | Inflammatory Bowel Diseases | 2012 | 32 |
| 38 | The prevalence and risk factors of psychological disorders, malnutrition and quality of life in IBD patients | Scandinavian Journal of Gastroenterology | 2019 | 32 |
| 39 | Expression of Cdx2 and Claudin-2 in the Multistage Tissue of Gastric Carcinogenesis | Oncology | 2007 | 31 |
| 40 | Perceptions of Chinese Biomedical Researchers Towards Academic Misconduct: A Comparison Between 2015 and 2010 | Science and Engineering Ethics | 2018 | 30 |
| 41 | Prophylactic somatostatin can reduce incidence of post-ERCP pancreatitis: multicenter randomized controlled trial | Endoscopy | 2015 | 28 |
| 42 | Guidelines for the diagnosis and treatment of alcoholic liver disease* | Journal of Digestive Diseases | 2008 | 27 |
| 43 | Associations of Genetic Variants in the PSCA, MUC1 and PLCE1 Genes with Stomach Cancer Susceptibility in a Chinese Population | PLoS ONE | 2015 | 26 |
| 44 | Tamoxifen can reverse multidrug resistance of colorectal carcinomain vivo | World Journal of Gastroenterology | 2005 | 25 |
| 45 | Standard treatment for Helicobacter pylori infection is suboptimal in non-ulcer dyspepsia compared with duodenal ulcer in Chinese | Alimentary Pharmacology and Therapeutics | 2005 | 24 |
| 46 | Involvement of Aquaporin 3 in Helicobacter pylori-Related Gastric Diseases | PLoS ONE | 2012 | 24 |
| 47 | Low expression of BARX2 in human primary hepatocellular carcinoma correlates with metastasis and predicts poor prognosis | Hepatology Research | 2015 | 24 |
| 48 | Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway | Oncogene | 2016 | 24 |
| 49 | Mechanisms of Probiotic VSL#3 in a Rat Model of Visceral Hypersensitivity Involves the Mast Cell-PAR2-TRPV1 Pathway | Digestive Diseases and Sciences | 2019 | 24 |
| 50 | Fecal Lactoferrin for Assessment of Inflammatory Bowel Disease Activity | Journal of Clinical Gastroenterology | 2020 | 24 |
