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Top Articles

#TitleJournalYearCitations
1The Genome Sequence of Drosophila melanogasterScience20005,566
2Genomic Expression Programs in the Response of Yeast Cells to Environmental ChangesMolecular Biology of the Cell20004,281
3Signals for Sorting of Transmembrane Proteins to Endosomes and LysosomesAnnual Review of Biochemistry20031,850
4Brefeldin A: insights into the control of membrane traffic and organelle structure.Journal of Cell Biology19921,827
5Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ERCell19891,710
6The Mechanisms of Vesicle Budding and FusionCell20041,628
7A Photoactivatable GFP for Selective Photolabeling of Proteins and CellsScience20021,518
8Activation of the OxyR Transcription Factor by Reversible Disulfide Bond FormationScience19981,112
9ER-to-Golgi transport visualized in living cellsNature19971,053
10Oxidative stressCurrent Opinion in Microbiology19991,017
11Development and Use of Fluorescent Protein Markers in Living CellsScience2003942
12Interaction of tyrosine-based sorting signals with clathrin-associated proteinsScience1995910
13Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane trafficCell1991829
14Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructureProceedings of the National Academy of Sciences of the United States of America2009816
15DNA Microarray-Mediated Transcriptional Profiling of the Escherichia coli Response to Hydrogen PeroxideJournal of Bacteriology2001752
16Protein degradation in the endoplasmic reticulumCell1990739
17Nuclear Membrane Dynamics and Reassembly in Living Cells: Targeting of an Inner Nuclear Membrane Protein in Interphase and MitosisJournal of Cell Biology1997738
18Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF proteinNature1992734
19Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translationScience1988706
20Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lckNature1989687
21Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.Proceedings of the National Academy of Sciences of the United States of America1990656
22Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transportCell1994654
23Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro.Proceedings of the National Academy of Sciences of the United States of America1991636
24Altered Trafficking of Lysosomal Proteins in Hermansky-Pudlak Syndrome Due to Mutations in the β3A Subunit of the AP-3 AdaptorMolecular Cell1999631
25UBIQUITIN AND THE CONTROL OF PROTEIN FATE IN THE SECRETORY AND ENDOCYTIC PATHWAYSAnnual Review of Cell and Developmental Biology1998586
26Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditionsScience1986579
27Kinetic Analysis of Secretory Protein Traffic and Characterization of Golgi to Plasma Membrane Transport Intermediates in Living CellsJournal of Cell Biology1998569
28Retrograde transport from endosomes to the trans-Golgi networkNature Reviews Molecular Cell Biology2006568
29An Expanding Universe of Noncoding RNAsScience2002562
30Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptorJournal of Cell Biology2004549
31A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expressionCell Metabolism2005547
32Analysis of Arabidopsis mutants deficient in flavonoid biosynthesisPlant Journal1995545
33Identification of the iron-responsive element for the translational regulation of human ferritin mRNAScience1987541
34Rapid Cycling of Lipid Raft Markers between the Cell Surface and Golgi ComplexJournal of Cell Biology2001496
35Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteinsCell1988493
36Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonistsScience1995488
37Golgi dispersal during microtubule disruption: regeneration of Golgi stacks at peripheral endoplasmic reticulum exit sites.Molecular Biology of the Cell1996488
38Structural Basis of the Redox Switch in the OxyR Transcription FactorCell2001484
39A Novel Clathrin Adaptor Complex Mediates Basolateral Targeting in Polarized Epithelial CellsCell1999479
40Complex Complexes: Signaling at the TCRImmunity1996478
41The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteinsProceedings of the National Academy of Sciences of the United States of America1997464
42Golgi Tubule Traffic and the Effects of Brefeldin A Visualized in Living CellsJournal of Cell Biology1997461
43T cell antigen receptor activation pathways: The tyrosine kinase connectionCell1991459
44A Small, Stable RNA Induced by Oxidative Stress: Role as a Pleiotropic Regulator and AntimutatorCell1997459
45Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor geneHuman Mutation1998452
46The Sm-like Hfq Protein Increases OxyS RNA Interaction with Target mRNAsMolecular Cell2002452
47Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in miceNature Genetics2001451
48Secretory Protein Trafficking and Organelle Dynamics in Living CellsAnnual Review of Cell and Developmental Biology2000449
49ADP-ribosylation factor, a small GTP-binding protein, is required for binding of the coatomer protein beta-COP to Golgi membranes.Proceedings of the National Academy of Sciences of the United States of America1992448
50The IL-2 receptor beta chain (p70): role in mediating signals for LAK, NK, and proliferative activitiesScience1987446