| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | Dopamine Receptors: From Structure to Function | Physiological Reviews | 1998 | 3,059 |
| 3 | Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter | Nature | 1996 | 2,267 |
| 4 | S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control | Nature | 1996 | 1,584 |
| 5 | Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers | Nature Biotechnology | 2015 | 1,487 |
| 6 | Basal cells as stem cells of the mouse trachea and human airway epithelium | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 1,296 |
| 7 | SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract | Cell | 2020 | 1,257 |
| 8 | Size and Shape of Protein Molecules at the Nanometer Level Determined by Sedimentation, Gel Filtration, and Electron Microscopy | Biological Procedures Online | 2009 | 1,194 |
| 9 | Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages | Cell | 1997 | 1,166 |
| 10 | Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation | Nature Medicine | 1998 | 1,079 |
| 11 | Mechanisms of Spreading Depression and Hypoxic Spreading Depression-Like Depolarization | Physiological Reviews | 2001 | 982 |
| 12 | Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes | Nature | 2010 | 965 |
| 13 | An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior | Cell | 2005 | 903 |
| 14 | Nitric oxide in skeletal muscle | Nature | 1994 | 898 |
| 15 | Immunoregulatory functions of surfactant proteins | Nature Reviews Immunology | 2005 | 877 |
| 16 | A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal | Genes and Development | 1998 | 876 |
| 17 | Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 849 |
| 18 | Retinoic acid regulates sex-specific timing of meiotic initiation in mice | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 842 |
| 19 | μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence | Nature | 2000 | 834 |
| 20 | The molecular elasticity of the extracellular matrix protein tenascin | Nature | 1998 | 820 |
| 21 | Role of Serotonin in the Paradoxical Calming Effect of Psychostimulants on Hyperactivity | Science | 1999 | 813 |
| 22 | The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium | Cell Stem Cell | 2009 | 793 |
| 23 | miwi, a Murine Homolog of piwi, Encodes a Cytoplasmic Protein Essential for Spermatogenesis | Developmental Cell | 2002 | 788 |
| 24 | A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration | Cell | 2006 | 762 |
| 25 | DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS | Annual Review of Neuroscience | 2004 | 755 |
| 26 | beta -Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3 | | 2000 | 752 |
| 27 | Distinct stem cells contribute to mammary gland development and maintenance | Nature | 2011 | 733 |
| 28 | Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants | Nature Immunology | 2003 | 718 |
| 29 | Recent Advances in the Molecular Biology of Dopamine Receptors | Annual Review of Neuroscience | 1993 | 692 |
| 30 | FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death | Cell | 2003 | 683 |
| 31 | Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells | Current Biology | 1998 | 682 |
| 32 | Mili, a mammalian member ofpiwifamily gene, is essential for spermatogenesis | Development (Cambridge) | 2004 | 666 |
| 33 | A standardized kinesin nomenclature | Journal of Cell Biology | 2004 | 662 |
| 34 | Molecular cloning and expression of the gene for a human D1 dopamine receptor | Nature | 1990 | 655 |
| 35 | Phosphatidylinositol 4,5-Bisphosphate Functions as a Second Messenger that Regulates Cytoskeleton–Plasma Membrane Adhesion | Cell | 2000 | 631 |
| 36 | Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling | DMM Disease Models and Mechanisms | 2010 | 627 |
| 37 | 2.0 Å Crystal Structure of a Four-Domain Segment of Human Fibronectin Encompassing the RGD Loop and Synergy Region | Cell | 1996 | 623 |
| 38 | Protein Kinase C as a Molecular Machine for Decoding Calcium and Diacylglycerol Signals | Cell | 1998 | 607 |
| 39 | The β 2 -adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 588 |
| 40 | Tenascin: An Extracellular Matrix Protein Prominent in Specialized Embryonic Tissues and Tumors | Annual Review of Cell Biology | 1989 | 582 |
| 41 | FtsZ in Bacterial Cytokinesis: Cytoskeleton and Force Generator All in One | Microbiology and Molecular Biology Reviews | 2010 | 533 |
| 42 | Mechanisms of Amphetamine Action Revealed in Mice Lacking the Dopamine Transporter | Journal of Neuroscience | 1998 | 526 |
| 43 | Male-to-Female Sex Reversal in Mice Lacking Fibroblast Growth Factor 9 | Cell | 2001 | 526 |
| 44 | AnkyrinG Is Required for Clustering of Voltage-gated Na Channels at Axon Initial Segments and for Normal Action Potential Firing | Journal of Cell Biology | 1998 | 517 |
| 45 | Akt/GSK3 Signaling in the Action of Psychotropic Drugs | Annual Review of Pharmacology and Toxicology | 2009 | 507 |
| 46 | Molecular characterization of the dopamine transporter | Trends in Pharmacological Sciences | 1993 | 503 |
| 47 | Association of β-Arrestin with G Protein-coupled Receptors during Clathrin-mediated Endocytosis Dictates the Profile of Receptor Resensitization | Journal of Biological Chemistry | 1999 | 501 |
| 48 | Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and ß-arrestin proteins | Progress in Neurobiology | 2002 | 493 |
| 49 | Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis | Journal of Cell Biology | 2000 | 489 |
| 50 | Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 488 |
